The It Ain't Magic Science Blog

Protein pileup affects social behavior through altered brain signaling

When a normal cellular cleanup process is disrupted, social behavior in mice is disrupted and they start behaving in ways that resemble human symptoms of autism spectrum disorder and schizophrenia.

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Diazoxide pills for Alzheimer’s disease?

Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.

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Carbon nanotubes, what are they good for?

Kylius Wilkins talks to Urs Frey and his recent success manufacturing carbon nanotubes (CNTs).

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Blood cell mutations linked to leukemia are inevitable

Researchers show that blood cell mutations increase with age identify risk factors for developing leukemia in Japanese and European populations.

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Black smokers and electroecosystems

Black smokers are deep-sea hydrothermal vents found in the ocean. Now scientists believe that they may host electroecosystems in which the primary producers use electric currents as their energy source.

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Zebrafish imagine a danger-free future to avoid threats in virtual reality

By imaging the brain while zebrafish “swim” in virtual reality, scientists have learned that even fish can create internal models to predict future outcomes.

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Apr

RIKEN is looking for you

by adam phillips | What's Up With Us

RIKEN is looking for you. Check out our new introductory videos! learn about exotic nuclei and much much more.

Apr

Promising mouse model for Ngly1 deficiency

by adam phillips | Hot Off the Press

A recent study of Ngly1 deficient mice used a secondary knockout to create double knockouts with symptoms similar to human NGLY1 deficiency.

Apr

Nihonium walk of fame

by jens wilkinson | Drop of science, What's Up With Us

A nihonium walk of fame is being built to commemorate the discovery of the 113th element

Apr

New rice fights off drought

by adam phillips | Hot Off the Press

Researchers have created drought resistant transgenic rice using a gene from a small Eurasian flowering plant

Apr

Centennial RIKEN Research

by adam phillips | Hot Off the Press

???This Spring we’ve put together a special centennial issue of RIKEN Research ???

Mar

Don’t know anything about RIKEN?

by adam phillips | What's Up With Us

Don’t know anything about RIKEN? We’ve made a new RIKEN booklet that should help!

Jan

Blocking obesity with a protein-sugar combination

by adam phillips | Hot Off the Press

Discovery of an enzyme that prevents obesity in mice through glycosylation of a protein involved fat-cell differentiation.

Dec

Robotic researcher to the rescue

by kylius wilkins | Drop of science, Interviews

Masaki Watabe talks about automated robotic researchers, future robot rule, and scientific philosophy.

Dec

RIKEN Research Winter Issue

by adam phillips | Hot Off the Press

It’s almost the end of the year and a here’s an early holiday present! The winter issue of RIKEN Research is here, covering plant parasites, depression, atomic clocks, and more! Enjoy!

Dec

The geometry of consciousness is a multi-dimensional math trip

by amanda alvarez | Research Highlight

Amanda Alvarez writes about how neuroscientists are studying consciousness with mathematics

Oct

RIKEN Research Fall Issue

by adam phillips | Hot Off the Press

Fall is here, and with it comes the latest issue of RIKEN Research. This issue covers tactile learning during sleep, supercomputers and simulations, solar cells, fly olfaction, tumor vaccines, and more

Sep

Locating social memories in the brain

by adam phillips | Hot Off the Press

Scientists have identified where social memories are stored in the brains of mice. Mice are forgotten because memories cannot be retrieved.

Sep

Big news in iPS cell transplants

by adam phillips | Hot Off the Press

iPS cell-derived retinal cells have been successfully transplanted from one monkey to another without need of immunosuppressant drugs.

Aug

In Japan, women in science seek allies, resources in push for gender equality

by amanda alvarez | What's Up With Us

neuroamanda talks about gender equality for female scientists is Japan.

Aug

Measuring altitude — with clocks?

by jens wilkinson | Drop of science

Measuring altitude using atomic clocks seems like a crazy idea, but it’s already being done at RIKEN in Japan

Aug

The sound of molecules: NMR-inspired music

by adam phillips | Research in Depth, Science Heavy

Science & art: how NMR works and how NMR spectra have been used to compose music based on molecular structures.

Aug

Eve Marder: freeing knowledge, crashing neurons

by amanda alvarez | Interviews

None of us would get on a plane that had its parts changed in mid-air, says Eve Marder, who has spent her career probing a very specific cluster of crustacean nerve cells. Yet we are all walking around undergoing a constant turnover of cellular parts, and so are the lobsters and crabs Marder studies.

Aug

RIKEN Research Summer issue

by adam phillips | Hot Off the Press

A quick post to let you know that the Summer issue of RIKEN Research Magazine came out towards the end of June. This issue covers brain evolution, regenerating skin, super-clear synapses, and much much more! Enjoy!

Aug

ESOF and the gimungous telescope

by adam phillips | What's Up With Us

Highlights from the recent EuroScience Open Forum (ESOF) conference held in Manchester (actually, pre-ESOF). Science was everywhere, even out by the sheep

Jun

Call for science-inspired art

by adam phillips | Drop of science, What's Up With Us

A rant about right-brain/left-brain pseudoscience and a call for science-inspired art. Scientists can be artists (and artists can be scientists)!

Jun

Why “nihonium”?

by jens wilkinson | Research Highlight

Kosuke Morita and Kouji Morimoto talked to reporters on Thursday morning about how they came up with name “nihonium” for element 113.

Jun

Nerd Nite comes to Tokyo

by jens wilkinson | What's Up With Us

Jens checks out Nerd Nite in Tokyo — swords and physics and brains oh my!

Jun

RIKEN Research Spring issue is here

by adam phillips | Hot Off the Press

Just a quick post to let you know that the Spring issue of RIKEN Research Magazine came out towards the end of March. This issue covers issues including the discovery of element 113, earth-friendly pesticides, and the secrets of a rice-killing fungal toxin. Enjoy!

Jun

Organ regeneration in the lab

by jens wilkinson | Interviews, What's Up With Us

Interview with Takashi Tsuji, team leader of the Laboratory for Organ Regeneration at the RIKEN Center for Developmental Biology

May

Of mice and NREM: In this brain circuit, memories depend on sleep

by amanda alvarez | Research Highlight

The parts of the brain responsible for creating a memory must be re-activated during a specific part of the sleep cycle for mice to remember.

Apr

Dear RIKEN: Can you bring frozen animals back to life?

by jens wilkinson | Dear RIKEN

Today we post our first Dear RIKEN question and answer.

Mar

From evolutionary morphology to Godzilla

by adam phillips | Interviews, What's Up With Us

I recently spoke with RIKEN scientist Shigeru Kuratani about evolutionary morphology, sci-fi monsters, the genius of Alien, and more.

Feb

Award-winning 3D images of living cells

by jens wilkinson | Interviews, What's Up With Us

An interview with Yuko Kiyosue, discussing the 3D images of living cells that gained her and her colleagues a recent award.

Jan

Electrolithoautotrophs

by adam phillips | Featured, Research in Depth

Learn what electrolithoautotrophs are and how the scientists proved that A. ferrooxidans can use electric potential to fuel growth.

Jan

Element 113: “discovery” or not?

by adam phillips | Drop of science

Recently four new synthetic elements were added to the periodic table. We asked Dr. Morita whether he thinks his team “discovered” or “created” element 113.

Dec

Black smokers and electroecosystems

by adam phillips | Research in Depth

Dec

Science communication symposium

by adam phillips | What's Up With Us

Friday I participated in a small symposium that focused on science communication (for institutions in Japan). We discussed using social media as a means to self-publish wow! and amazing! research findings. Here are some of my thoughts about how useful this plays out in Japan.

Dec

RIKEN at a glance

by adam phillips | Hot Off the Press

We’ve just gotten our order of RIKEN at a Glance booklets back from the printers, and they look fantastic. Follow the link to download your electronic copy now!

Dec

About this blog

by adam phillips | What's Up With Us

Read about the purpose of our blog and what we hope to achieve with it.

Dec

Let the blogging begin!

by jens wilkinson | What's Up With Us

Welcome to the It Ain’t Magic science blog! (brought to you by the RIKEN Global Communications Team)

Zebrafish imagine a danger-free future to avoid threats in virtual reality

By imaging the brain while zebrafish “swim” in virtual reality, scientists have learned that even fish can create internal models to predict future outcomes.

Read on

Cancer cells killed with artificial glycosylated metalloenzyme

Scientists have developed two cancer therapies that use an artificial glycosylated metalloenzyme to specifically target cancer cells in mice.

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A new type of cell death discovered in fly guts

A completely unknown type of cell death called “erebosis” has been discovered in the guts of the common fruit fly.

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Pulses of light can enhance superconductivity

Pulses of light could be used to turn materials into superconductors through an unconventional type of superconductivity.

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Opto-OISI: imaging connections in the living brain

A new imaging technique called opto-OISI allows scientists to non-invasively visualize where specific neurons project in the living brain.

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Implantable blastocyst‐like cysts grown from stem cells

Embryo Organoids?! Blastocyst‐like cysts grown from pluripotent mouse stem cells were similar to natural blastocysts (early embryos).

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Mar

Decision-making during the COVID-19 pandemic

by jens wilkinson | Interviews

COVID-19 series — installment #2: RIKEN CBS Unit Leader Rei Akaishi talks about government decision-making during the pandemic.

Mar

Confronting a string of epidemics including COVID-19

by jens wilkinson | Interviews

COVID-19 series — installment #1: RIKEN Executive Director Shigeo Koyasu talks about epidemics and what a good response looks like.

Feb

Next stop: clinical hair regeneration

by adam phillips | Featured, Hot Off the Press

A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.

Jan

Godzilla-sized zooplankton for better aquafarming

by masataka sasabe | Hot Off the Press

Scientists have created extra large zooplankton to help feed the fish in aquafarms. The new plankton were created using an ion beam to generate mutations.

Dec

Electric rays to help us map the ocean floor

by adam phillips | Hot Off the Press

Electric rays and sting rays could map the ocean floor through their natural behavior, helping us find resources and collect data on other ocean life.

Nov

Bacterial drug resistance studied by robotic E. coli evolution

by masataka sasabe | Hot Off the Press

Experimentally evolving E. coli under pressure from a large number of antibiotics was able to identify constraints underlying evolved drug resistance.

Nov

New artificial skin helps avoid animal testing

by masataka sasabe | Hot Off the Press

A new artificial skin that reproduces proper tension can be used to research skin function and disease while reducing the need to experiment on animals.

Oct

Social novelty in the brain: haven’t I seen you someplace before?

by adam phillips | Hot Off the Press

Social novelty and contextual novelty are segregated in the SuM region of the hypothalamus and in projections to the hippocampus, allowing memories of meeting new people to be formed separately from memories of new places.

Sep

FABP4: A preschool-aged biomarker for autism

by adam phillips | Hot Off the Press

Reduced FABP4 was found in preschool-aged children with autism spectrum disorder, making it a potential new biomarker for the condition.

New lab-grown retinal sheets almost ready for clinical trials

A new retinal transplant technique works by preventing bipolar cells from maturing in lab-grown retinal sheets.

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New treatment assembles cancer drug inside the body

Cancer drugs assembled inside the body on cancer cells should reduce harmful side effects to other tissue.

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Diazoxide pills for Alzheimer’s disease?

Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.

Read on

Artificial gravity protects the immune system of mice in space

Mice who experienced artificial gravity on the ISS suffered less damage to their immune system (thymus) than weightless mice did.

Read on

Oct

Zebrafish imagine a danger-free future to avoid threats in virtual reality

by amanda alvarez | Hot Off the Press

By imaging the brain while zebrafish “swim” in virtual reality, scientists have learned that even fish can create internal models to predict future outcomes.

Continue!

Sep

Kleefstra syndrome in mice reversed after birth

by adam phillips | Hot Off the Press

Researchers used a postnatal supply of GLP to reverse neural and behavioral symptoms of Kleefstra syndrome in mice!

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Sep

A faster and more sensitive antibody test for COVID-19

by masataka sasabe | Hot Off the Press

Fast and sensitive: A new antibody test for the COVID-19 virus. Just a pinprick of blood and results in 30 minutes.

Continue!

Jul

Opossums are the first genome edited marsupials

by masataka sasabe | Featured, Hot Off the Press

A new piezoelectronic microinjection method has allowed the first successful genome editing in marsupials: albino opossums.

Continue!

Jul

Methylation mutation directly linked to autism

by adam phillips | Hot Off the Press

A mutation in a gene needed for H3K9 methylation is directly linked to autism spectrum disorders and early neurodevelopment.

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Jun

Melatonin in mice, circadian rhythms, and daily torpor

by amanda alvarez | Hot Off the Press

A new breed of lab mouse allows the study of naturally occurring melatonin. These mice will adjust better to jetlag than regular lab mice and experience daily torpor.

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