The It Ain't Magic Science Blog

Superfly flight simulator helps unravel navigation in the brain

Optical imaging neural activity in flies as they use a flight simulator can help us understand how the brain codes navigation.

Cyborg microchip valve driven by earthworm muscle

This earthworm muscle-controlled biological microelectromechanical system (bio‐MEMS) could lead the way to next-generation medical implants.

Eve Marder: freeing knowledge, crashing neurons

None of us would get on a plane that had its parts changed in mid-air, says Eve Marder, who has spent her career probing a very specific cluster of crustacean nerve cells. Yet we are all walking around undergoing a constant turnover of cellular parts, and so are the lobsters and crabs Marder studies.

Gut bacteria double team worsens symptoms of multiple sclerosis

Joint activity of two gut bacteria leads to excessive MOG-specific T-cell activity and demyelination of neurons in the spinal cord of a mouse model of multiple sclerosis.

New artificial skin helps avoid animal testing

A new artificial skin that reproduces proper tension can be used to research skin function and disease while reducing the need to experiment on animals.

Super-thin wearable electronics just got more flexible

A method for making super-flexible and ultra-thin wearable electronics uses water-vapor plasma to create gold-gold bonds.

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20

Extra “eye” movements are the key to better self-driving cars

Extra “eye” movements are the key to better self-driving cars

by adam phillips | Hot Off the Press

If self-driving cars make saccades like people, they might make fewer mistakes identifying important features of the road.

26

Palaeospondylus: mystery of vertebrate evolution solved

Palaeospondylus: mystery of vertebrate evolution solved

by adam phillips | Hot Off the Press

Micro-CT scans using synchrotron radiation X-rays reveal Palaeospondylus morphology, finally allowing its placement on the evolutionary tree.

28

Xist knockout rescues miscarriages in mice

Xist knockout rescues miscarriages in mice

by adam phillips | Hot Off the Press

Xist knockout rescues miscarriages in mice whose egg cells lack H3K27me3 epigenetic instructions.

27

A new type of cell death discovered in fly guts

A new type of cell death discovered in fly guts

by masataka sasabe | Hot Off the Press

A completely unknown type of cell death called “erebosis” has been discovered in the guts of the common fruit fly.

6

Diagnosing fetal heart disease benefits from explanatory AI

Diagnosing fetal heart disease benefits from explanatory AI

by adam phillips | Hot Off the Press

Diagnosis accuracy improved when doctors used explanatory AI to help diagnose congenital heart disease from fetal ultrasound videos.

5

Chaos theory provides hints for controlling the weather

Chaos theory provides hints for controlling the weather

by jens wilkinson | Hot Off the Press

Computer simulations were used to show that small adjustments to certain variables in the weather system could modify weather phenomena such as sudden downpours.

29

Robotic exoskeleton learns to help people stand up

Robotic exoskeleton learns to help people stand up

by jens wilkinson | Hot Off the Press

This new robotic exoskeleton uses machine learning to know when users want help standing up.

25

Nanocarrier spray: better crops without genetic modification

Nanocarrier spray: better crops without genetic modification

by adam phillips | Hot Off the Press

Gene expression, but not genomes, altered in plants and crops with a spray containing bioactive molecules tethered to nanocarrier peptides

16

Introducing Nikola, the emotional android boy

Introducing Nikola, the emotional android boy

by adam phillips | Featured, Hot Off the Press

A new android named Nikola will help researchers study facial expressions, emotions, and social interactions.

15

Green hydrogen production for fuel cells and fertilizers

Green hydrogen production for fuel cells and fertilizers

by adam phillips | Featured, Hot Off the Press

A new method of water electrolysis avoids rare metals, making hydrogen production green and sustainable.

9

Social contact-seeking behavior and loneliness in the brain

Social contact-seeking behavior and loneliness in the brain

by adam phillips | Featured, Hot Off the Press

Levels of the peptide amylin in the brain are related to loneliness; activating amylin neurons in the MPOA drives isolated mice to seek social contact.

4

New treatment assembles cancer drug inside the body

New treatment assembles cancer drug inside the body

by masataka sasabe | Featured, Hot Off the Press

Cancer drugs assembled inside the body on cancer cells should reduce harmful side effects to other tissue.

27

New lab-grown retinal sheets almost ready for clinical trials

New lab-grown retinal sheets almost ready for clinical trials

by adam phillips | Featured, Hot Off the Press

A new retinal transplant technique works by preventing bipolar cells from maturing in lab-grown retinal sheets.

17

The free-energy principle explains neural network behavior

The free-energy principle explains neural network behavior

by adam phillips | Hot Off the Press

Scientists show that the free-energy principle can explain how neural networks work.

13

How does gravity affect antimatter?

How does gravity affect antimatter?

by jens wilkinson | Featured, Hot Off the Press

Scientists find that antimatter reacts to gravity the same way that regular matter does.

23

Super-thin wearable electronics just got more flexible

Super-thin wearable electronics just got more flexible

by adam phillips | Featured, Hot Off the Press

A method for making super-flexible and ultra-thin wearable electronics uses water-vapor plasma to create gold-gold bonds.

17

Cassava engineered to produce healthier tapioca starch

Cassava engineered to produce healthier tapioca starch

by adam phillips | Hot Off the Press

Reducing the amount of starch branching enzymes in cassava plants made more resistant and thus healthier tapioca starch.

10

Diazoxide pills for Alzheimer’s disease?

Diazoxide pills for Alzheimer’s disease?

by adam phillips | Featured, Hot Off the Press

Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.

8

Zebrafish imagine a danger-free future to avoid threats in virtual reality

Zebrafish imagine a danger-free future to avoid threats in virtual reality

by amanda alvarez | Hot Off the Press

By imaging the brain while zebrafish “swim” in virtual reality, scientists have learned that even fish can create internal models to predict future outcomes.

22

Kleefstra syndrome in mice reversed after birth

Kleefstra syndrome in mice reversed after birth

by adam phillips | Hot Off the Press

Researchers used a postnatal supply of GLP to reverse neural and behavioral symptoms of Kleefstra syndrome in mice!

10

A faster and more sensitive antibody test for COVID-19

A faster and more sensitive antibody test for COVID-19

by masataka sasabe | Hot Off the Press

Fast and sensitive: A new antibody test for the COVID-19 virus. Just a pinprick of blood and results in 30 minutes.

26

Opossums are the first genome edited marsupials

Opossums are the first genome edited marsupials

by masataka sasabe | Featured, Hot Off the Press

A new piezoelectronic microinjection method has allowed the first successful genome editing in marsupials: albino opossums.

19

Methylation mutation directly linked to autism

Methylation mutation directly linked to autism

by adam phillips | Hot Off the Press

A mutation in a gene needed for H3K9 methylation is directly linked to autism spectrum disorders and early neurodevelopment.

25

Melatonin in mice, circadian rhythms, and daily torpor

Melatonin in mice, circadian rhythms, and daily torpor

by amanda alvarez | Hot Off the Press

A new breed of lab mouse allows the study of naturally occurring melatonin. These mice will adjust better to jetlag than regular lab mice and experience daily torpor.

2

Why (mouse) mothers take risks to protect their infants

Why (mouse) mothers take risks to protect their infants

by adam phillips | Featured, Hot Off the Press

The calcitonin receptor and its ligand amylin act in the brain to motivate mouse mothers to protect their pups, even in risky/dangerous situations.

26

Dietary amino acid linked to cancer in flies

Dietary amino acid linked to cancer in flies

by masataka sasabe | Hot Off the Press

Researchers have found a dietary amino acid linked to oncogene expression / tumor formation; reduced consumption reduced cancer in flies.

30

Cancer cells killed with artificial glycosylated metalloenzyme

Cancer cells killed with artificial glycosylated metalloenzyme

by adam phillips | Hot Off the Press

Scientists have developed two cancer therapies that use an artificial glycosylated metalloenzyme to specifically target cancer cells in mice.

9

H2AK119ub1: How you inherit acquired traits from your mom

H2AK119ub1: How you inherit acquired traits from your mom

by adam phillips | Featured, Hot Off the Press

H2AK119ub1. Say that three times really fast! But seriously, it allows maternally acquired traits to be inherited.

8

COVID-19: Changing the way we do research

COVID-19: Changing the way we do research

by jens wilkinson | Interviews

COVID-19 series — Part #4: Team Leader Aki Minoda from RIKEN IMS talks about how the pandemic has affected the way we work.

26

Telework: a societal game-changer

Telework: a societal game-changer

by jens wilkinson | Interviews

COVID-19 series — installment #3: Team Leader Osamu Sakura (@RIKEN Center for Advanced Intelligence Project) talks about how the pandemic has affected society through the need for telework.

18

Decision-making during the COVID-19 pandemic

Decision-making during the COVID-19 pandemic

by jens wilkinson | Interviews

COVID-19 series — installment #2: RIKEN CBS Unit Leader Rei Akaishi talks about government decision-making during the pandemic.

5

Confronting a string of epidemics including COVID-19

Confronting a string of epidemics including COVID-19

by jens wilkinson | Interviews

COVID-19 series — installment #1: RIKEN Executive Director Shigeo Koyasu talks about epidemics and what a good response looks like.

19

Next stop: clinical hair regeneration

Next stop: clinical hair regeneration

by adam phillips | Featured, Hot Off the Press

A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.

22

Godzilla-sized zooplankton for better aquafarming

Godzilla-sized zooplankton for better aquafarming

by masataka sasabe | Hot Off the Press

Scientists have created extra large zooplankton to help feed the fish in aquafarms. The new plankton were created using an ion beam to generate mutations.

10

Electric rays to help us map the ocean floor

Electric rays to help us map the ocean floor

by adam phillips | Hot Off the Press

Electric rays and sting rays could map the ocean floor through their natural behavior, helping us find resources and collect data on other ocean life.

26

Bacterial drug resistance studied by robotic E. coli evolution

Bacterial drug resistance studied by robotic E. coli evolution

by masataka sasabe | Hot Off the Press

Experimentally evolving E. coli under pressure from a large number of antibiotics was able to identify constraints underlying evolved drug resistance.

9

New artificial skin helps avoid animal testing

New artificial skin helps avoid animal testing

by masataka sasabe | Hot Off the Press

A new artificial skin that reproduces proper tension can be used to research skin function and disease while reducing the need to experiment on animals.

2

Social novelty in the brain: haven’t I seen you someplace before?

Social novelty in the brain: haven’t I seen you someplace before?

by adam phillips | Hot Off the Press

Social novelty and contextual novelty are segregated in the SuM region of the hypothalamus and in projections to the hippocampus, allowing memories of meeting new people to be formed separately from memories of new places.

11

FABP4: A preschool-aged biomarker for autism

FABP4: A preschool-aged biomarker for autism

by adam phillips | Hot Off the Press

Reduced FABP4 was found in preschool-aged children with autism spectrum disorder, making it a potential new biomarker for the condition.

Organ regeneration in the lab

Interview with Takashi Tsuji, team leader of the Laboratory for Organ Regeneration at the RIKEN Center for Developmental Biology

Gray matter volume links symptoms in autism

Low gray matter volume in the posterior superior parietal lobule (pSPL) was found to correlate with specific cognitive and perceptual symptoms of autism.

Blood cell mutations linked to leukemia are inevitable

Researchers show that blood cell mutations increase with age identify risk factors for developing leukemia in Japanese and European populations.

Protons are lighter than previously thought

A new and most precise measurement of protons shows that they are lighter than previously thought.

Cancer cells killed with artificial glycosylated metalloenzyme

Scientists have developed two cancer therapies that use an artificial glycosylated metalloenzyme to specifically target cancer cells in mice.

Chaos theory provides hints for controlling the weather

Computer simulations were used to show that small adjustments to certain variables in the weather system could modify weather phenomena such as sudden downpours.

20

Extra “eye” movements are the key to better self-driving cars

Extra “eye” movements are the key to better self-driving cars

by adam phillips | Hot Off the Press

If self-driving cars make saccades like people, they might make fewer mistakes identifying important features of the road.

26

Palaeospondylus: mystery of vertebrate evolution solved

Palaeospondylus: mystery of vertebrate evolution solved

by adam phillips | Hot Off the Press

Micro-CT scans using synchrotron radiation X-rays reveal Palaeospondylus morphology, finally allowing its placement on the evolutionary tree.

28

Xist knockout rescues miscarriages in mice

Xist knockout rescues miscarriages in mice

by adam phillips | Hot Off the Press

Xist knockout rescues miscarriages in mice whose egg cells lack H3K27me3 epigenetic instructions.

27

A new type of cell death discovered in fly guts

A new type of cell death discovered in fly guts

by masataka sasabe | Hot Off the Press

A completely unknown type of cell death called “erebosis” has been discovered in the guts of the common fruit fly.

6

Diagnosing fetal heart disease benefits from explanatory AI

Diagnosing fetal heart disease benefits from explanatory AI

by adam phillips | Hot Off the Press

Diagnosis accuracy improved when doctors used explanatory AI to help diagnose congenital heart disease from fetal ultrasound videos.

5

Chaos theory provides hints for controlling the weather

Chaos theory provides hints for controlling the weather

by jens wilkinson | Hot Off the Press

Computer simulations were used to show that small adjustments to certain variables in the weather system could modify weather phenomena such as sudden downpours.

29

Robotic exoskeleton learns to help people stand up

Robotic exoskeleton learns to help people stand up

by jens wilkinson | Hot Off the Press

This new robotic exoskeleton uses machine learning to know when users want help standing up.

25

Nanocarrier spray: better crops without genetic modification

Nanocarrier spray: better crops without genetic modification

by adam phillips | Hot Off the Press

Gene expression, but not genomes, altered in plants and crops with a spray containing bioactive molecules tethered to nanocarrier peptides

16

Introducing Nikola, the emotional android boy

Introducing Nikola, the emotional android boy

by adam phillips | Featured, Hot Off the Press

A new android named Nikola will help researchers study facial expressions, emotions, and social interactions.

New lab-grown retinal sheets almost ready for clinical trials

A new retinal transplant technique works by preventing bipolar cells from maturing in lab-grown retinal sheets.

Social contact-seeking behavior and loneliness in the brain

Levels of the peptide amylin in the brain are related to loneliness; activating amylin neurons in the MPOA drives isolated mice to seek social contact.

Why (mouse) mothers take risks to protect their infants

The calcitonin receptor and its ligand amylin act in the brain to motivate mouse mothers to protect their pups, even in risky/dangerous situations.

New treatment assembles cancer drug inside the body

Cancer drugs assembled inside the body on cancer cells should reduce harmful side effects to other tissue.

20

Extra “eye” movements are the key to better self-driving cars

Extra “eye” movements are the key to better self-driving cars

by adam phillips | Hot Off the Press

If self-driving cars make saccades like people, they might make fewer mistakes identifying important features of the road.

26

Palaeospondylus: mystery of vertebrate evolution solved

Palaeospondylus: mystery of vertebrate evolution solved

by adam phillips | Hot Off the Press

Micro-CT scans using synchrotron radiation X-rays reveal Palaeospondylus morphology, finally allowing its placement on the evolutionary tree.

28

Xist knockout rescues miscarriages in mice

Xist knockout rescues miscarriages in mice

by adam phillips | Hot Off the Press

Xist knockout rescues miscarriages in mice whose egg cells lack H3K27me3 epigenetic instructions.

27

A new type of cell death discovered in fly guts

A new type of cell death discovered in fly guts

by masataka sasabe | Hot Off the Press

A completely unknown type of cell death called “erebosis” has been discovered in the guts of the common fruit fly.

6

Diagnosing fetal heart disease benefits from explanatory AI

Diagnosing fetal heart disease benefits from explanatory AI

by adam phillips | Hot Off the Press

Diagnosis accuracy improved when doctors used explanatory AI to help diagnose congenital heart disease from fetal ultrasound videos.

5

Chaos theory provides hints for controlling the weather

Chaos theory provides hints for controlling the weather

by jens wilkinson | Hot Off the Press

Computer simulations were used to show that small adjustments to certain variables in the weather system could modify weather phenomena such as sudden downpours.