Topics
Are you “at risk” of being a habitual coffee drinker?
Several single nucleotide polymorphisms (SNPs) are related to dietary habits, including coffee, tea, tofu, and yogurt consumption.
Astrocytes powered by norepinephrine during fear-memory formation
Brain wave synchrony can predict memory age
The degree of neuronal synchrony between the anterior cingulate cortex and the hippocampus during recall is an indication of memory age (in mice).
AI identifies features associated with cancer recurrence
Artificial intelligence has successfully identified features relevant to cancer prognosis that were not previously noted by pathologists
Longevity in supercentenarians linked to cytotoxic T-cells
Blood analysis in supercentenarians showed that they have many more cytotoxic CD4 T-cells than people with average life spans.
Schizophrenia biomarker (hydrogen sulfide) in human hair
Not only is hydrogen sulfide a good biomarker for schizophrenia, it’s also the culprit and a new starting point for drug discovery.
Brain tissue kept alive for weeks with new microfluidic device
A new microfluidic device can keep tissue cultures functional for weeks on an artificial membrane
Massive filaments, galaxies, and supermassive black holes
Big telescopes yield big data! Detailed observations gas filaments connecting galaxies in a distant proto-cluster in the early Universe.
Understanding non-coding DNA: gene “enhancers”
NETCAGE is a newly developed technique for determining the structure of portions of the non-coding genome called ‘enhancers.’
Implantable blastocyst‐like cysts grown from stem cells
Embryo Organoids?! Blastocyst‐like cysts grown from pluripotent mouse stem cells were similar to natural blastocysts (early embryos).
Toward micro-hearts: tiny pumps driven by self-organizing cardiomyocytes
Self-organizing cardiomyocytes on flexible polydimethylsiloxane sheets form tiny pumps. This is the first step towards building micro-hearts.
Talking science Illustration with Misaki Ouchida
Whether it’s bird anatomy or science cartoons, Masaki Ouchida can do it all. She spoke with us about her career in science illustration, from the US to Japan.
Cyborg microchip valve driven by earthworm muscle
This earthworm muscle-controlled biological microelectromechanical system (bio‐MEMS) could lead the way to next-generation medical implants.
Eating a high fat diet without getting obese?
Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.
New metalloenzyme system selectively targets cancer cells
Specific targeting of cancer cells and onsite drug synthesis has been achieved using a new artificial metalloenzyme delivery system.
Boosting betaine may be a treatment for schizophrenia
Supplementing model mice with glycine betaine (trimethylglycine), a compound originally derived from beets, can alleviate symptoms of schizophrenia.
Gray matter volume links symptoms in autism
Low gray matter volume in the posterior superior parietal lobule (pSPL) was found to correlate with specific cognitive and perceptual symptoms of autism.
New mechanism allows lower energy requirement for OLED displays
Scientists have found a way to significantly reduce the amount of energy required by organic light emitting diodes (OLED) displays.
CAPON links Alzheimer’s plaques to neurodegeneration
CAPON was found to link Aβ plaques and hippocampal neurodegeneration in mice, explaining how these two hallmarks of Alzheimer’s disease are related.
AdR blockers protect the brain from stroke damage
Treatment with adrenergic receptor antagonists (AdR blockers) was able to reduce stroke-related brain damage in mice and improve motor recovery.
Trigger region found for epileptic absence seizures
A mouse model shows that absence seizures are triggered by faulty connections between the cortex and fast-spiking neurons in the striatum.
Opto-OISI: imaging connections in the living brain
A new imaging technique called opto-OISI allows scientists to non-invasively visualize where specific neurons project in the living brain.
Flies smell through a gore-tex system
The newly named gore-tex gene is responsible for the development of nanopores that allow chemicals in the air to be detected (in flies).
Protein pileup affects social behavior through altered brain signaling
When a normal cellular cleanup process is disrupted, social behavior in mice is disrupted and they start behaving in ways that resemble human symptoms of autism spectrum disorder and schizophrenia.
The joys of computational mass spectrometry
Scientists have developed a new automated computational mass spectrometry system that can search an organism’s entire metabolome for as-yet-unknown metabolites (potential drugs).
Pulses of light can enhance superconductivity
Pulses of light could be used to turn materials into superconductors through an unconventional type of superconductivity.
Scientists create new type of self-healing material
This newly created ethylene-based material has shape memory that allows self-healing!
Brain clock ticks differently in autism
A new brain imaging study shows that autistic severity is linked to how long certain regions of the brain store information.
Supermassive black holes still dark and mysterious
For the first time, scientists have measured the strength of magnetic fields near supermassive black holes and something doesn’t add up.
Evolution of the inner ear: insights from jawless fish
A new story for inner ear evolution based on the developmental patterning found in hagfish, one of two extant jawless vertebrates and a link to the last common ancestor of modern jawed vertebrates.
Tumor detection during breast cancer surgery
Scientists have developed a new way to accurately detect the margins between cancerous and non-cancerous tissue during breast cancer surgery.
Smarter AI: machine learning without negative data
Scientists have developed a new method for machine learning that allows an AI to make better classifications without negative data.
Nerdnite recap: When the brainbow met the boson
Fun times at nerdnite tokyo. Brains, bosons, and math, oh my!
Mutations, CRISPR, and spinocerebellar ataxia
Scientists discover that mutations causing the degenerative movement disorder spinocerebellar ataxia type 29 work by disrupting calcium release of neurons inside the brain.
Gene regulator that allows plant rehydration after drought
New genetic insights into the plant rehydration process: this is why your plants don’t die after you forgot to water them.
Researchers create a functional salivary gland organoid 🤤
Scientists have succeeded in growing three-dimensional salivary gland tissue that produced saliva like normal glands when implanted into mice.
Getting a grip on slow but unique shark evolution
Scientists have decoded the genomes of two species of shark, bringing the grand total of sequenced shark genomes to three.
Ig Nobel awards: Silly experiments that strike gold
Amanda writes about the Ig Nobel awards after founder Marc Abrahams visited nerdnite Tokyo. Science at its best!
A self-powered heart monitor taped to the skin
A group of scientists have developed a human-friendly, ultra-flexible organic sensor powered by sunlight, which acts as a self-powered heart monitor.
Are you “at risk” of being a habitual coffee drinker?
Several single nucleotide polymorphisms (SNPs) are related to dietary habits, including coffee, tea, tofu, and yogurt consumption.
Astrocytes powered by norepinephrine during fear-memory formation
Brain wave synchrony can predict memory age
The degree of neuronal synchrony between the anterior cingulate cortex and the hippocampus during recall is an indication of memory age (in mice).
AI identifies features associated with cancer recurrence
Artificial intelligence has successfully identified features relevant to cancer prognosis that were not previously noted by pathologists
Longevity in supercentenarians linked to cytotoxic T-cells
Blood analysis in supercentenarians showed that they have many more cytotoxic CD4 T-cells than people with average life spans.
Schizophrenia biomarker (hydrogen sulfide) in human hair
Not only is hydrogen sulfide a good biomarker for schizophrenia, it’s also the culprit and a new starting point for drug discovery.
Brain tissue kept alive for weeks with new microfluidic device
A new microfluidic device can keep tissue cultures functional for weeks on an artificial membrane
Massive filaments, galaxies, and supermassive black holes
Big telescopes yield big data! Detailed observations gas filaments connecting galaxies in a distant proto-cluster in the early Universe.
Understanding non-coding DNA: gene “enhancers”
NETCAGE is a newly developed technique for determining the structure of portions of the non-coding genome called ‘enhancers.’
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Are you “at risk” of being a habitual coffee drinker?
Several single nucleotide polymorphisms (SNPs) are related to dietary habits, including coffee, tea, tofu, and yogurt consumption.
24
Astrocytes powered by norepinephrine during fear-memory formation
19
Brain wave synchrony can predict memory age
The degree of neuronal synchrony between the anterior cingulate cortex and the hippocampus during recall is an indication of memory age (in mice).
18
AI identifies features associated with cancer recurrence
Artificial intelligence has successfully identified features relevant to cancer prognosis that were not previously noted by pathologists
15
Longevity in supercentenarians linked to cytotoxic T-cells
Blood analysis in supercentenarians showed that they have many more cytotoxic CD4 T-cells than people with average life spans.
29
Schizophrenia biomarker (hydrogen sulfide) in human hair
Not only is hydrogen sulfide a good biomarker for schizophrenia, it’s also the culprit and a new starting point for drug discovery.