Two genes that regulate how much we dream


An international research team led by RIKEN BDR has identified a pair of genes that regulate how much REM (dream) and non-REM sleep an animal experiences.

Promising mouse model for Ngly1 deficiency


A recent study of Ngly1 deficient mice used a secondary knockout to create double knockouts with symptoms similar to human NGLY1 deficiency.

From evolutionary morphology to Godzilla


I recently spoke with RIKEN scientist Shigeru Kuratani about evolutionary morphology, sci-fi monsters, the genius of Alien, and more.

Massive filaments, galaxies, and supermassive black holes


Big telescopes yield big data! Detailed observations gas filaments connecting galaxies in a distant proto-cluster in the early Universe.

Cubes of brain tissue allow drug discovery without animals


Modeling the blood-brain-barrier with brains-in-a-cube allows drug testing without the need for animals.

Skipping fatty acids could be recipe for schizophrenia


Prenatal lack of omega-3 and omega-6 fatty acids linked to epigenetic changes that lead to schizophrenic symptoms in mice.

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This gut microbe might protect against diabetes and reduce insulin resistance

NEW: One-way hydrogel guides motion of tiny worms!

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Dec

21

The stars align

The stars align


The stars align. That’s what you say, when things work out perfectly. In the case of an eclipse, of course, it’s not stars that align but rather the moon and sun.

Xist knockout rescues miscarriages in mice


Xist knockout rescues miscarriages in mice whose egg cells lack H3K27me3 epigenetic instructions.

Atlas of the aging lipidome highlights kidneys and gut bacteria


The atlas revealed sex differences in the aging kidney lipidome and lipid byproducts of gut bacteria that accumulate throughout the body.

AI identifies features associated with cancer recurrence


Artificial intelligence has successfully identified features relevant to cancer prognosis that were not previously noted by pathologists

Smoker gut bacteria reduce bowel inflammation in ulcerative colitis


Mouth bacteria that settle in the guts of smokers activate helper T-cells that counter inflammation in ulcerative colitis.

Strong emotions plus non-REM sleep equals longer-lasting perceptual memories


Perceptual memories linked to positive emotions, such as joy or happiness, are strengthened during sleep, specifically during periods of deep non-REM sleep.

Why (mouse) mothers take risks to protect their infants


The calcitonin receptor and its ligand amylin act in the brain to motivate mouse mothers to protect their pups, even in risky/dangerous situations.

Next stop: clinical hair regeneration


A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.

Talking science Illustration with Misaki Ouchida


Whether it’s bird anatomy or science cartoons, Masaki Ouchida can do it all. She spoke with us about her career in science illustration, from the US to Japan.

Eating a high fat diet without getting obese?


Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.

How does gravity affect antimatter?


Scientists find that antimatter reacts to gravity the same way that regular matter does.