Cancer cells killed with artificial glycosylated metalloenzyme


Scientists have developed two cancer therapies that use an artificial glycosylated metalloenzyme to specifically target cancer cells in mice.

Memories are made of this ?? – (Part 2)


Thomas McHugh from the RIKEN Center for Brain Science continues his discussion about memories, emotions, the brain, and life.

Astrocytes powered by norepinephrine during fear-memory formation


Norepinephrine released in the locus coeruleus during fear learning is accompanied by increased calcium and cAMP levels in nearby astrocytes.

Cassava engineered to produce healthier tapioca starch


Reducing the amount of starch branching enzymes in cassava plants made more resistant and thus healthier tapioca starch.

The joys of computational mass spectrometry


Scientists have developed a new automated computational mass spectrometry system that can search an organism’s entire metabolome for as-yet-unknown metabolites (potential drugs).

Solar cells you can put in the wash


Scientists have developed ultra-thin photovoltaic solar cells that can be incorporated into fabric and even washed.

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This gut microbe might protect against diabetes and reduce insulin resistance

NEW: One-way hydrogel guides motion of tiny worms!

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Dec

21

The stars align

The stars align


The stars align. That’s what you say, when things work out perfectly. In the case of an eclipse, of course, it’s not stars that align but rather the moon and sun.

Decision-making during the COVID-19 pandemic


COVID-19 series — installment #2: RIKEN CBS Unit Leader Rei Akaishi talks about government decision-making during the pandemic.

Scientists solve epigenetic barriers to cloning


Scientists show that two epigenetic factors improve the success rate of cloning via somatic cell nuclear transfer.

Opto-OISI: imaging connections in the living brain


A new imaging technique called opto-OISI allows scientists to non-invasively visualize where specific neurons project in the living brain.

Bacterial drug resistance studied by robotic E. coli evolution


Experimentally evolving E. coli under pressure from a large number of antibiotics was able to identify constraints underlying evolved drug resistance.

Root growth improved in soil contaminated with cesium


Overactivating the ABA signaling pathway in plants prevented cesium in soil from blocking root growth in plants.

Promising mouse model for Ngly1 deficiency


A recent study of Ngly1 deficient mice used a secondary knockout to create double knockouts with symptoms similar to human NGLY1 deficiency.

New lab-grown retinal sheets almost ready for clinical trials


A new retinal transplant technique works by preventing bipolar cells from maturing in lab-grown retinal sheets.

Diazoxide pills for Alzheimer’s disease?


Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.

Social contact-seeking behavior and loneliness in the brain


Levels of the peptide amylin in the brain are related to loneliness; activating amylin neurons in the MPOA drives isolated mice to seek social contact.

Eating a high fat diet without getting obese?


Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.