The It Ain't Magic Science Blog

Promising mouse model for Ngly1 deficiency

A recent study of Ngly1 deficient mice used a secondary knockout to create double knockouts with symptoms similar to human NGLY1 deficiency.

Geostationary satellite enables better precipitation and flood predictions

Data from the Himawari-8 geosynchronous satellite was used in weather simulations to improve forecasts of sudden precipitation and tropical storm development.

Godzilla-sized zooplankton for better aquafarming

Scientists have created extra large zooplankton to help feed the fish in aquafarms. The new plankton were created using an ion beam to generate mutations.

Real webshooters? Synthetic spider silk spun from artificial gland

Scientists create a microfluidic device that spins artificial spider silk from spidroins proteins, duplicating silk’s complex molecular structure.

Schizophrenia biomarker (hydrogen sulfide) in human hair

Not only is hydrogen sulfide a good biomarker for schizophrenia, it’s also the culprit and a new starting point for drug discovery.

Cubes of brain tissue allow drug discovery without animals

Modeling the blood-brain-barrier with brains-in-a-cube allows drug testing without the need for animals.

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Self-assembly of spider silk

This gut microbe might protect against diabetes and reduce insulin resistance

NEW: One-way hydrogel guides motion of tiny worms!

Latest Posts

24

Brainless memory makes the spinal cord smarter than previously thought

Brainless memory makes the spinal cord smarter than previously thought

by adam phillips | Hot Off the Press

The spinal cord learns how to direct limb muscles to avoid aversive sensations and recalls the memories using separate neural circuitry. Oh, and without a brain!

22

Eco-friendly ammonia production for fertilizers and alternative fuel

Eco-friendly ammonia production for fertilizers and alternative fuel

by adam phillips | Hot Off the Press

A new process that allows ammonia to be produced using much less energy than the standard methods.

11

Cubes of brain tissue allow drug discovery without animals

Cubes of brain tissue allow drug discovery without animals

by masataka sasabe | Hot Off the Press

Modeling the blood-brain-barrier with brains-in-a-cube allows drug testing without the need for animals.

3

Gut bacteria could help overcome milk allergy

Gut bacteria could help overcome milk allergy

by adam phillips | Hot Off the Press

Analysis shows that some gut bacteria could help improve oral immunotherapy against milk allergy.

2

Detecting pathogens: the evolution of plant immunity

Detecting pathogens: the evolution of plant immunity

by masataka sasabe | Hot Off the Press

Scientists find recognition receptors for plant growth and plant immunity that share a common evolutionary origin.

21

Genomic “butterfly effect” involving TADs explains risk for autism

Genomic “butterfly effect” involving TADs explains risk for autism

by masataka sasabe | Hot Off the Press

De novo mutations in three-dimensional structures in the genome containing known ASD genes were found to be associated with ASD risk.

19

Heat used to transform antiskyrmions to skyrmions and back

Heat used to transform antiskyrmions to skyrmions and back

by jens wilkinson | Hot Off the Press

Scientists discover a way to transform antiskyrmions to skyrmions and back using heat and magnetic fields.

23

Real webshooters? Synthetic spider silk spun from artificial gland

Real webshooters? Synthetic spider silk spun from artificial gland

by adam phillips | Hot Off the Press

Scientists create a microfluidic device that spins artificial spider silk from spidroins proteins, duplicating silk’s complex molecular structure.

15

Omics Omics Omics: Analysis predicts ovarian cancer-treating drug

Omics Omics Omics: Analysis predicts ovarian cancer-treating drug

by adam phillips | Hot Off the Press

Multi-omics analysis prediction: drugs that inhibit Ras signaling will help prevent tumor formation in serous ovarian cancer.

27

First hydride-ion battery that works at room temperature

First hydride-ion battery that works at room temperature

by adam phillips | Hot Off the Press

Researchers develop a new solid electrolyte that can conduct hydride ions, thus allowing better hydrogen-based batteries and fuel cells.

10

Plants to the rescue: cleaning up our dirty soil

Plants to the rescue: cleaning up our dirty soil

by adam phillips | Drop of science

A brief review of phytoremediation and research into how plants can be used to clean the environment.

1

Stolen genes used for parasitic mind control

Stolen genes used for parasitic mind control

by masataka sasabe | Hot Off the Press

Parasitic horsehair worms evolved to control their praying mantis hosts by stealing their genes (horizontal gene transfer).

27

Machine learning contributes to better quantum error correction

Machine learning contributes to better quantum error correction

by jens wilkinson | Hot Off the Press

Researchers have developed an autonomous method for handling error correction in quantum computing. This will help quantum computers maintain their advantages over standard computers.

20

Laser melting ice-core sampler for studying climate change

Laser melting ice-core sampler for studying climate change

by adam phillips | Hot Off the Press

This laser melting ice core sampler can determine temperature changes thousands of years ago on very fine timescale.

31

Gut bacteria reduces insulin resistance, protects against diabetes

Gut bacteria reduces insulin resistance, protects against diabetes

by adam phillips | Hot Off the Press

Scientists discover gut bacteria that reduce insulin resistance in your body and sugar in your poo.

23

Scary places burned into our minds by constant memory replay

Scary places burned into our minds by constant memory replay

by riken research highlights | Research Highlight

Researchers discover the mechanism through which places associated with negative experiences are burned into our memories.

18

Toward human hibernation: cold-resistant mouse stem cells

Toward human hibernation: cold-resistant mouse stem cells

by adam phillips | Hot Off the Press

Cold-resistant stem cells from “deep torpor” mice are a big step toward understanding why tissue survives hibernation.

15

A researcher’s journey part 2: emotional memory and being human

A researcher’s journey part 2: emotional memory and being human

by adam phillips | Interviews

Joshua Johansen from RIKEN CBS explains emotional memory, what his lab is doing, and what makes a good researcher.

8

Mathematical model predicts self-organized learning in real neurons

Mathematical model predicts self-organized learning in real neurons

by adam phillips | Hot Off the Press

The free energy principle predicted how real neural connections changed as neurons “learned” in a dish.

7

Deadly fungi beaten with fatty acid synthase inhibitor

Deadly fungi beaten with fatty acid synthase inhibitor

by adam phillips | Hot Off the Press

A new approach to attacking fungi involves inhibiting a gene needed for making fatty acids.

12

A new and improved way to store hydrogen

A new and improved way to store hydrogen

by masataka sasabe | Hot Off the Press

A simple chemical reaction allows hydrogen-carrying ammonia to be stored and retrieved cheaply and easily.

29

A new alpha-particle treatment for multiple cancers

A new alpha-particle treatment for multiple cancers

by adam phillips | Hot Off the Press

A new type of alpha-particle therapy allows selective targeting of tumors in multiple cancers.

28

A researcher’s journey: from surfing to studying pain

A researcher’s journey: from surfing to studying pain

by adam phillips | Interviews

Joshua Johansen from RIKEN CBS tells us about his journey from surfer to pain researcher and beyond. Stay tuned for part II …

15

The first drug treatment for brain aneurysms (in mice)

The first drug treatment for brain aneurysms (in mice)

by adam phillips | Hot Off the Press

Scientists discover that most aneurysms result from mutations. A mouse model shows they can be treated with drugs.

12

Simple but revolutionary modular organoids

Simple but revolutionary modular organoids

by jens wilkinson | Hot Off the Press

A new way to construct complex 3D organoids without using elaborate techniques! The trick using modular cubes with hydrogel layers.

19

Thoughts on the genetics of medicinal licorice

Thoughts on the genetics of medicinal licorice

by jens wilkinson | Drop of science

Jens talks about licorice and a recent RIKEN study that finally mapped its genome.

24

Pathogenic genetic variation linked to H. pylori-related stomach cancer

Pathogenic genetic variation linked to H. pylori-related stomach cancer

by adam phillips | Hot Off the Press

Researchers find that the risk of stomach cancer due to infection withH. Pylori bacteria increases with specific genetic variations.

29

ERRg predicts atrial fibrillation and hidden comorbidity

ERRg predicts atrial fibrillation and hidden comorbidity

by adam phillips | Hot Off the Press

Polygenic risk scores based on the genetic data from more that a million people predicted atrial fibrillation, stroke, and mortality.

27

Memories are made of this ?? – (Part 2)

Memories are made of this ?? – (Part 2)

by adam phillips | Interviews

Thomas McHugh from the RIKEN Center for Brain Science continues his discussion about memories, emotions, the brain, and life.

26

Replicating opossum heart regeneration to help fight cardiovascular disease

Replicating opossum heart regeneration to help fight cardiovascular disease

by adam phillips | Research Animation

Animated research highlight: Opossum hearts hint at new ways of fighting cardiovascular disease

26

Spacey, nerdy nights in Tokyo

Spacey, nerdy nights in Tokyo

by kelly jackson | What's Up With Us

Kelly, our new It Ain’t Magic contributor, writes about her nerdy nighttime experiences in Tokyo.

16

Memories are made of this ? ? – (Part 1)

Memories are made of this ? ? – (Part 1)

by adam phillips | Interviews

Brain science ’round midnight episode 8: Thomas McHugh from the RIKEN Center for Brain Science discusses memories and the brain

18

Hibernation-like state can protect kidneys during heart surgery

Hibernation-like state can protect kidneys during heart surgery

by adam phillips | Hot Off the Press

Activating Q-neurons in the mouse brain led to a hibernation-like state that protected kidneys during heart surgery.

14

Crying baby? Science says walk, then sit

Crying baby? Science says walk, then sit

by adam phillips | Hot Off the Press

Recipe for success: Walk 5 min, sit 8 min, lay no-longer-crying baby down. Now you can relax.

6

Cyborg cockroaches to the rescue!

Cyborg cockroaches to the rescue!

by masataka sasabe | Hot Off the Press

The key to this remote-controllable cyborg cockroach is a solar-cell rechargeable battery and an ultrathin flexible backpack.

25

Ethanol pretreated soil protects plants from drought

Ethanol pretreated soil protects plants from drought

by adam phillips | Hot Off the Press

Pretreating soil with ethanol protected plants, including wheat and rice, from the adverse effects of water deprivation.

22

Marsupial heart regeneration ability given to mice

Marsupial heart regeneration ability given to mice

by adam phillips | Hot Off the Press

Regeneration of mouse hearts ? ?? after birth achieved by figuring out how it’s possible in opossums.

19

How an herbal medicine protects against inflamed bowels

How an herbal medicine protects against inflamed bowels

by adam phillips | Hot Off the Press

A Japanese herbal medicine promotes good bacteria and innate immune cells in the gut, which protects against intestinal inflammation.

7

Robotic AI helps efficient growth of replacement organs

Robotic AI helps efficient growth of replacement organs

by masataka sasabe | Hot Off the Press

Humans team-up with a robotic AI to speed up experiments to find the best way to regrow damaged eye tissue from stem cells.

Consciousness, brain connections, and the claustrum

Research shows that the claustrum acts as a ‘consciousness conductor’ that synchronizes and connects areas within the mouse brain.

Mathematical model predicts self-organized learning in real neurons

The free energy principle predicted how real neural connections changed as neurons “learned” in a dish.

Robotic researcher to the rescue

Masaki Watabe talks about automated robotic researchers, future robot rule, and scientific philosophy.

Low-protein diet changes sperm and health of future offspring

Low-protein diets in male mice alter sperm and result in offspring that have metabolic problems like diabetes in adulthood.

Telework: a societal game-changer

COVID-19 series — installment #3: Team Leader Osamu Sakura (@RIKEN Center for Advanced Intelligence Project) talks about how the pandemic has affected society through the need for telework.

Decision-making during the COVID-19 pandemic

COVID-19 series — installment #2: RIKEN CBS Unit Leader Rei Akaishi talks about government decision-making during the pandemic.

24

Brainless memory makes the spinal cord smarter than previously thought

Brainless memory makes the spinal cord smarter than previously thought

by adam phillips | Hot Off the Press

The spinal cord learns how to direct limb muscles to avoid aversive sensations and recalls the memories using separate neural circuitry. Oh, and without a brain!

22

Eco-friendly ammonia production for fertilizers and alternative fuel

Eco-friendly ammonia production for fertilizers and alternative fuel

by adam phillips | Hot Off the Press

A new process that allows ammonia to be produced using much less energy than the standard methods.

11

Cubes of brain tissue allow drug discovery without animals

Cubes of brain tissue allow drug discovery without animals

by masataka sasabe | Hot Off the Press

Modeling the blood-brain-barrier with brains-in-a-cube allows drug testing without the need for animals.

3

Gut bacteria could help overcome milk allergy

Gut bacteria could help overcome milk allergy

by adam phillips | Hot Off the Press

Analysis shows that some gut bacteria could help improve oral immunotherapy against milk allergy.

2

Detecting pathogens: the evolution of plant immunity

Detecting pathogens: the evolution of plant immunity

by masataka sasabe | Hot Off the Press

Scientists find recognition receptors for plant growth and plant immunity that share a common evolutionary origin.

21

Genomic “butterfly effect” involving TADs explains risk for autism

Genomic “butterfly effect” involving TADs explains risk for autism

by masataka sasabe | Hot Off the Press

De novo mutations in three-dimensional structures in the genome containing known ASD genes were found to be associated with ASD risk.

19

Heat used to transform antiskyrmions to skyrmions and back

Heat used to transform antiskyrmions to skyrmions and back

by jens wilkinson | Hot Off the Press

Scientists discover a way to transform antiskyrmions to skyrmions and back using heat and magnetic fields.

23

Real webshooters? Synthetic spider silk spun from artificial gland

Real webshooters? Synthetic spider silk spun from artificial gland

by adam phillips | Hot Off the Press

Scientists create a microfluidic device that spins artificial spider silk from spidroins proteins, duplicating silk’s complex molecular structure.

15

Omics Omics Omics: Analysis predicts ovarian cancer-treating drug

Omics Omics Omics: Analysis predicts ovarian cancer-treating drug

by adam phillips | Hot Off the Press

Multi-omics analysis prediction: drugs that inhibit Ras signaling will help prevent tumor formation in serous ovarian cancer.

Green hydrogen production for fuel cells and fertilizers

A new method of water electrolysis avoids rare metals, making hydrogen production green and sustainable.

Transgenic plants ??on acid survive without water

Scientists designed transgenic plants that survive drought-like conditions by bumping up acetic acid production only when water is scarce.

Eating a high fat diet without getting obese?

Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.

New lab-grown retinal sheets almost ready for clinical trials

A new retinal transplant technique works by preventing bipolar cells from maturing in lab-grown retinal sheets.

24

Brainless memory makes the spinal cord smarter than previously thought

Brainless memory makes the spinal cord smarter than previously thought

by adam phillips | Hot Off the Press

The spinal cord learns how to direct limb muscles to avoid aversive sensations and recalls the memories using separate neural circuitry. Oh, and without a brain!

22

Eco-friendly ammonia production for fertilizers and alternative fuel

Eco-friendly ammonia production for fertilizers and alternative fuel

by adam phillips | Hot Off the Press

A new process that allows ammonia to be produced using much less energy than the standard methods.

11

Cubes of brain tissue allow drug discovery without animals

Cubes of brain tissue allow drug discovery without animals

by masataka sasabe | Hot Off the Press

Modeling the blood-brain-barrier with brains-in-a-cube allows drug testing without the need for animals.

3

Gut bacteria could help overcome milk allergy

Gut bacteria could help overcome milk allergy

by adam phillips | Hot Off the Press

Analysis shows that some gut bacteria could help improve oral immunotherapy against milk allergy.

2

Detecting pathogens: the evolution of plant immunity

Detecting pathogens: the evolution of plant immunity

by masataka sasabe | Hot Off the Press

Scientists find recognition receptors for plant growth and plant immunity that share a common evolutionary origin.

21

Genomic “butterfly effect” involving TADs explains risk for autism

Genomic “butterfly effect” involving TADs explains risk for autism

by masataka sasabe | Hot Off the Press

De novo mutations in three-dimensional structures in the genome containing known ASD genes were found to be associated with ASD risk.