The It Ain't Magic Science Blog

RIKEN at a glance

We’ve just gotten our order of RIKEN at a Glance booklets back from the printers, and they look fantastic. Follow the link to download your electronic copy now!

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Deep-brain exploration with nanomaterials

A new way to optogenetically activate neurons deep in the brain using infrared light and upconversion nanoparticles. It’s non-invasive!

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Boosting betaine may be a treatment for schizophrenia

Supplementing model mice with glycine betaine (trimethylglycine), a compound originally derived from beets, can alleviate symptoms of schizophrenia.

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Flies smell through a gore-tex system

The newly named gore-tex gene is responsible for the development of nanopores that allow chemicals in the air to be detected (in flies).

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Massive filaments, galaxies, and supermassive black holes

Big telescopes yield big data! Detailed observations gas filaments connecting galaxies in a distant proto-cluster in the early Universe.

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Centennial RIKEN Research

???This Spring we’ve put together a special centennial issue of RIKEN Research ???

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Topics

Apr

Why being sick can create anxiety

by riken research highlights | Research Highlight

Researchers have linked changes in mouse immune-cell metabolism to anxiety-related behavior and alterations in brain chemistry.

Apr

Plant hormone combats dehydration

by adam phillips | Hot Off the Press

Scientists show that CLE25 is a plant hormone that travels from roots to leaves and helps close stomata in times of dehydration stress.

Mar

Heat shock system helps dried up bug come back to life

by jens wilkinson | Hot Off the Press

An international collaboration has determined that cooption of the Heat Shock Factor (HSF) gene system is what allows larvae of the sleeping chironomid to be able to survive severe desiccation.

Feb

In living color: imaging the brain with synthetic bioluminescence

by amanda alvarez | Hot Off the Press

A new way to image the brain from outside the head using bioluminescence.

Feb

Deep-brain exploration with nanomaterials

by amanda alvarez | Hot Off the Press

A new way to optogenetically activate neurons deep in the brain using infrared light and upconversion nanoparticles. It’s non-invasive!

Feb

Running away from carbon dioxide: the terminal connection

by adam phillips | Hot Off the Press

Even fish want to avoid carbon dioxide. Now we know that they can because of chemosensation and the Terminal Nerve.

Jan

Rainbow engineering to make the brain glow

by amanda alvarez | Drop of science

Bar talk about tinkering with bioluminescent molecules from jellyfish, corals, and algae, figuring out how they work, and making them more useful for brain science.

Jan

Geostationary satellite enables better precipitation and flood predictions

by jens wilkinson | Hot Off the Press

Data from the Himawari-8 geosynchronous satellite was used in weather simulations to improve forecasts of sudden precipitation and tropical storm development.

Jan

Clean and green: a moss that removes lead (Pb) from water

by adam phillips | Hot Off the Press

Scientists show that the moss Funaria hygrometrica can remove harmful lead from water when in the protonema stage of development.

Jan

The brain’s GPS has a buddy system

by amanda alvarez | Hot Off the Press

In addition to encoding self location, brain cells in the rat hippocampus act like a GPS that encodes the location of other rats.

Dec

Leaky plants bad for drought resistance

by adam phillips | Research in Depth

The KAI2 receptor for compounds found in smoke helps plants retain water and survive during drought.

Dec

Helping the body clock keep its cool

by riken research highlights | Research Highlight

Two parallel temperature-responsive mechanisms ensure that circadian rhythms are not skewed by changes in temperature

Dec

The stars align

by amanda alvarez | Drop of science

The stars align. That’s what you say, when things work out perfectly. In the case of an eclipse, of course, it’s not stars that align but rather the moon and sun.

Dec

What’s that smell? The advantage of sniffing

by adam phillips | Hot Off the Press

Rhythmic sniffing boosts phase-coded neuronal signals in the mouse olfactory bulb that allow odors to be identified.

Nov

Quantum dots light up cancer with a little help

by riken research highlights | Research Highlight

Researchers have found a small connecting protein that can help make quantum dot-based probes for biomedical imaging.

Nov

Most precise measurement ever of proton magnetic moment

by jens wilkinson | Hot Off the Press

Using a sophisticated setup, scientists have made the most precise measurement to date of the proton magnetic moment.

Nov

Proton and antiproton still seem identical

by jens wilkinson | Hot Off the Press

Using a novel two-particle measurement method, scientists have measured the magnetic moment of the antiproton at a precision 350 times higher than any previous measurement.

Nov

Microcolumns: elementary neuronal units that carpet the (mouse) brain

by amanda alvarez | Hot Off the Press

A hexagonal lattice organizes major cell types in the cerebral cortex, with similar cells synchronizing their activity in microcolumns.

Oct

Jupiter’s volcano-powered auroral lights

by riken research highlights | Research Highlight

A collaborative effort used data from NASA’s Juno spacecraft to explain the transient auroras found on Jupiter.

Oct

Hepatoma (liver cancer) blocked by a sugar look-a-like

by adam phillips | Hot Off the Press

A sugar (fucose) analog can prevent liver cancer (hepatoma) from invading healthy liver cells.

Oct

Random movements help color-detecting cells form the proper pattern

by jens wilkinson | Hot Off the Press

Scientists have used a mathematical model to explain why zebrafish cone cells in the eye are arranged in a specific pattern in all individuals.

Sep

Visualizing chick-brain morphogenesis

by riken research highlights | Research Highlight

A new statistical-based method provides insight into the morphogenesis of developing organs.

Sep

Skin-like wearable electronics

by riken research highlights | Research Highlight

Sensors made from stretchable nanomesh allow skin to breathe naturally while continuously monitoring patient health.

Sep

Solar cells you can put in the wash

by jens wilkinson | Hot Off the Press

Scientists have developed ultra-thin photovoltaic solar cells that can be incorporated into fabric and even washed.

Sep

Learning and unlearning to fear: The two faces of noradrenaline

by adam phillips | Hot Off the Press

Fear association and unlearning fear association require different populations of noradrenaline neurons in the locus coeruleus.

Sep

ּּּBigger oocytes = more mistakes

by riken research highlights | Research Highlight

The large size of mouse oocytes is shown to create errors when chromosomes divide between daughter cells.

Sep

Superfly flight simulator helps unravel navigation in the brain

by adam phillips | Hot Off the Press

Optical imaging neural activity in flies as they use a flight simulator can help us understand how the brain codes navigation.

Sep

Skipping fatty acids could be recipe for schizophrenia

by adam phillips | Hot Off the Press

Prenatal lack of omega-3 and omega-6 fatty acids linked to epigenetic changes that lead to schizophrenic symptoms in mice.

Aug

A gut-wrenching defense against parasitic worms

by riken research highlights | Research Highlight

Mast cells in the gut help fight off parasitic worms in the early stages of infection.

Aug

Memory retrieval needs a neuronal connecting flight

by adam phillips | Hot Off the Press

Scientists use optogenetics to discover a part of the brain necessary for retrieving memories of personal experiences.

Aug

From egg to embryo

by riken research highlights | Research Highlight

A newly discovered gene turns off an egg’s egginess, allowing it to become an embryo.

Aug

This nickel catalyst bats from both sides of the plate

by riken research highlights | Research Highlight

Scientists discover that a nickel catalyst acts as both a acid and a base during molecule assembly.

Jul

New info about how chromosomes form

by riken research highlights | Research Highlight

Fewer components are needed for chromosome assembly during cell division than previously supposed.

Jul

Tracking how stars grow up in a virtual playground

by amanda alvarez | Research Highlight

Amanda Alvarez writes about Steven Rieder and his research in modeling clusters of growing new stars.

Jul

Protons are lighter than previously thought

by jens wilkinson | Hot Off the Press

A new and most precise measurement of protons shows that they are lighter than previously thought.

Jul

Untangling depression in Huntington’s disease

by riken research highlights | Research Highlight

New research implicates clumps of insoluble, misfolded proteins in the development of mental illness in people with Huntington’s disease

Jul

Imaging whole-body cancer metastasis at the single-cell level

by adam phillips | Hot Off the Press

A new optical clearing method allows imaging of cancer metastasis at incredibly high resolution.

Jun

Meet the editors: the growing pains of scientific publishing

by amanda alvarez | What's Up With Us

Amanda Alvarez writes about the recent seminars at RIKEN by Philip Campbell and Emilie Marcus, the editors-in-chief of Nature and Cell.

May

Carbon nanotubes, what are they good for?

by kylius wilkins | Interviews, What's Up With Us

Kylius Wilkins talks to Urs Frey and his recent success manufacturing carbon nanotubes (CNTs).

Plant peptide spells relief from salty stress

Newly discovered plant peptide hormone can be used to protect plants from excessive environmental salt.

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Opossums are the first genome edited marsupials

A new piezoelectronic microinjection method has allowed the first successful genome editing in marsupials: albino opossums.

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Cyborg microchip valve driven by earthworm muscle

This earthworm muscle-controlled biological microelectromechanical system (bio‐MEMS) could lead the way to next-generation medical implants.

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Eating a high fat diet without getting obese?

Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.

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RIKEN at a glance

We’ve just gotten our order of RIKEN at a Glance booklets back from the printers, and they look fantastic. Follow the link to download your electronic copy now!

Read on

Trigger region found for epileptic absence seizures

A mouse model shows that absence seizures are triggered by faulty connections between the cortex and fast-spiking neurons in the striatum.

Read on

Sep

A faster and more sensitive antibody test for COVID-19

by masataka sasabe | Hot Off the Press

Fast and sensitive: A new antibody test for the COVID-19 virus. Just a pinprick of blood and results in 30 minutes.

Jul

Opossums are the first genome edited marsupials

by masataka sasabe | Featured, Hot Off the Press

A new piezoelectronic microinjection method has allowed the first successful genome editing in marsupials: albino opossums.

Jul

Methylation mutation directly linked to autism

by adam phillips | Hot Off the Press

A mutation in a gene needed for H3K9 methylation is directly linked to autism spectrum disorders and early neurodevelopment.

Jun

Melatonin in mice, circadian rhythms, and daily torpor

by amanda alvarez | Hot Off the Press

A new breed of lab mouse allows the study of naturally occurring melatonin. These mice will adjust better to jetlag than regular lab mice and experience daily torpor.

Jun

Why (mouse) mothers take risks to protect their infants

by adam phillips | Featured, Hot Off the Press

The calcitonin receptor and its ligand amylin act in the brain to motivate mouse mothers to protect their pups, even in risky/dangerous situations.

May

Dietary amino acid linked to cancer in flies

by masataka sasabe | Hot Off the Press

Researchers have found a dietary amino acid linked to oncogene expression / tumor formation; reduced consumption reduced cancer in flies.

Apr

Cancer cells killed with artificial glycosylated metalloenzyme

by adam phillips | Hot Off the Press

Scientists have developed two cancer therapies that use an artificial glycosylated metalloenzyme to specifically target cancer cells in mice.

Apr

H2AK119ub1: How you inherit acquired traits from your mom

by adam phillips | Featured, Hot Off the Press

H2AK119ub1. Say that three times really fast! But seriously, it allows maternally acquired traits to be inherited.

Apr

COVID-19: Changing the way we do research

by jens wilkinson | Interviews

COVID-19 series — Part #4: Team Leader Aki Minoda from RIKEN IMS talks about how the pandemic has affected the way we work.

New lab-grown retinal sheets almost ready for clinical trials

A new retinal transplant technique works by preventing bipolar cells from maturing in lab-grown retinal sheets.

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Green hydrogen production for fuel cells and fertilizers

A new method of water electrolysis avoids rare metals, making hydrogen production green and sustainable.

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How does gravity affect antimatter?

Scientists find that antimatter reacts to gravity the same way that regular matter does.

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Opossums are the first genome edited marsupials

A new piezoelectronic microinjection method has allowed the first successful genome editing in marsupials: albino opossums.

Read on

Feb

New treatment assembles cancer drug inside the body

by masataka sasabe | Featured, Hot Off the Press

Cancer drugs assembled inside the body on cancer cells should reduce harmful side effects to other tissue.

Continue!

Jan

New lab-grown retinal sheets almost ready for clinical trials

by adam phillips | Featured, Hot Off the Press

A new retinal transplant technique works by preventing bipolar cells from maturing in lab-grown retinal sheets.

Continue!

Jan

The free-energy principle explains neural network behavior

by adam phillips | Hot Off the Press

Scientists show that the free-energy principle can explain how neural networks work.

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Jan

How does gravity affect antimatter?

by jens wilkinson | Featured, Hot Off the Press

Scientists find that antimatter reacts to gravity the same way that regular matter does.

Continue!

Dec

Super-thin wearable electronics just got more flexible

by adam phillips | Featured, Hot Off the Press

A method for making super-flexible and ultra-thin wearable electronics uses water-vapor plasma to create gold-gold bonds.

Continue!

Dec

Cassava engineered to produce healthier tapioca starch

by adam phillips | Hot Off the Press

Reducing the amount of starch branching enzymes in cassava plants made more resistant and thus healthier tapioca starch.

Continue!

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