The It Ain't Magic Science Blog

Brain tissue kept alive for weeks with new microfluidic device

A new microfluidic device can keep tissue cultures functional for weeks on an artificial membrane

Decision-making during the COVID-19 pandemic

COVID-19 series — installment #2: RIKEN CBS Unit Leader Rei Akaishi talks about government decision-making during the pandemic.

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Talking science Illustration with Misaki Ouchida

Whether it’s bird anatomy or science cartoons, Masaki Ouchida can do it all. She spoke with us about her career in science illustration, from the US to Japan.

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AdR blockers protect the brain from stroke damage

Treatment with adrenergic receptor antagonists (AdR blockers) was able to reduce stroke-related brain damage in mice and improve motor recovery.

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New metalloenzyme system selectively targets cancer cells

Specific targeting of cancer cells and onsite drug synthesis has been achieved using a new artificial metalloenzyme delivery system.

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The sound of molecules: NMR-inspired music

Science & art: how NMR works and how NMR spectra have been used to compose music based on molecular structures.

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Topics

Jan

The brain’s GPS has a buddy system

by amanda alvarez | Hot Off the Press

In addition to encoding self location, brain cells in the rat hippocampus act like a GPS that encodes the location of other rats.

Dec

Leaky plants bad for drought resistance

by adam phillips | Research in Depth

The KAI2 receptor for compounds found in smoke helps plants retain water and survive during drought.

Dec

Helping the body clock keep its cool

by riken research highlights | Research Highlight

Two parallel temperature-responsive mechanisms ensure that circadian rhythms are not skewed by changes in temperature

Dec

The stars align

by amanda alvarez | Drop of science

The stars align. That’s what you say, when things work out perfectly. In the case of an eclipse, of course, it’s not stars that align but rather the moon and sun.

Dec

What’s that smell? The advantage of sniffing

by adam phillips | Hot Off the Press

Rhythmic sniffing boosts phase-coded neuronal signals in the mouse olfactory bulb that allow odors to be identified.

Nov

Quantum dots light up cancer with a little help

by riken research highlights | Research Highlight

Researchers have found a small connecting protein that can help make quantum dot-based probes for biomedical imaging.

Nov

Most precise measurement ever of proton magnetic moment

by jens wilkinson | Hot Off the Press

Using a sophisticated setup, scientists have made the most precise measurement to date of the proton magnetic moment.

Nov

Proton and antiproton still seem identical

by jens wilkinson | Hot Off the Press

Using a novel two-particle measurement method, scientists have measured the magnetic moment of the antiproton at a precision 350 times higher than any previous measurement.

Nov

Microcolumns: elementary neuronal units that carpet the (mouse) brain

by amanda alvarez | Hot Off the Press

A hexagonal lattice organizes major cell types in the cerebral cortex, with similar cells synchronizing their activity in microcolumns.

Oct

Jupiter’s volcano-powered auroral lights

by riken research highlights | Research Highlight

A collaborative effort used data from NASA’s Juno spacecraft to explain the transient auroras found on Jupiter.

Oct

Hepatoma (liver cancer) blocked by a sugar look-a-like

by adam phillips | Hot Off the Press

A sugar (fucose) analog can prevent liver cancer (hepatoma) from invading healthy liver cells.

Oct

Random movements help color-detecting cells form the proper pattern

by jens wilkinson | Hot Off the Press

Scientists have used a mathematical model to explain why zebrafish cone cells in the eye are arranged in a specific pattern in all individuals.

Sep

Visualizing chick-brain morphogenesis

by riken research highlights | Research Highlight

A new statistical-based method provides insight into the morphogenesis of developing organs.

Sep

Skin-like wearable electronics

by riken research highlights | Research Highlight

Sensors made from stretchable nanomesh allow skin to breathe naturally while continuously monitoring patient health.

Sep

Solar cells you can put in the wash

by jens wilkinson | Hot Off the Press

Scientists have developed ultra-thin photovoltaic solar cells that can be incorporated into fabric and even washed.

Sep

Learning and unlearning to fear: The two faces of noradrenaline

by adam phillips | Hot Off the Press

Fear association and unlearning fear association require different populations of noradrenaline neurons in the locus coeruleus.

Sep

ּּּBigger oocytes = more mistakes

by riken research highlights | Research Highlight

The large size of mouse oocytes is shown to create errors when chromosomes divide between daughter cells.

Sep

Superfly flight simulator helps unravel navigation in the brain

by adam phillips | Hot Off the Press

Optical imaging neural activity in flies as they use a flight simulator can help us understand how the brain codes navigation.

Sep

Skipping fatty acids could be recipe for schizophrenia

by adam phillips | Hot Off the Press

Prenatal lack of omega-3 and omega-6 fatty acids linked to epigenetic changes that lead to schizophrenic symptoms in mice.

Aug

A gut-wrenching defense against parasitic worms

by riken research highlights | Research Highlight

Mast cells in the gut help fight off parasitic worms in the early stages of infection.

Aug

Memory retrieval needs a neuronal connecting flight

by adam phillips | Hot Off the Press

Scientists use optogenetics to discover a part of the brain necessary for retrieving memories of personal experiences.

Aug

From egg to embryo

by riken research highlights | Research Highlight

A newly discovered gene turns off an egg’s egginess, allowing it to become an embryo.

Aug

This nickel catalyst bats from both sides of the plate

by riken research highlights | Research Highlight

Scientists discover that a nickel catalyst acts as both a acid and a base during molecule assembly.

Jul

New info about how chromosomes form

by riken research highlights | Research Highlight

Fewer components are needed for chromosome assembly during cell division than previously supposed.

Jul

Tracking how stars grow up in a virtual playground

by amanda alvarez | Research Highlight

Amanda Alvarez writes about Steven Rieder and his research in modeling clusters of growing new stars.

Jul

Protons are lighter than previously thought

by jens wilkinson | Hot Off the Press

A new and most precise measurement of protons shows that they are lighter than previously thought.

Jul

Untangling depression in Huntington’s disease

by riken research highlights | Research Highlight

New research implicates clumps of insoluble, misfolded proteins in the development of mental illness in people with Huntington’s disease

Jul

Imaging whole-body cancer metastasis at the single-cell level

by adam phillips | Hot Off the Press

A new optical clearing method allows imaging of cancer metastasis at incredibly high resolution.

Jun

Meet the editors: the growing pains of scientific publishing

by amanda alvarez | What's Up With Us

Amanda Alvarez writes about the recent seminars at RIKEN by Philip Campbell and Emilie Marcus, the editors-in-chief of Nature and Cell.

May

Carbon nanotubes, what are they good for?

by kylius wilkins | Interviews, What's Up With Us

Kylius Wilkins talks to Urs Frey and his recent success manufacturing carbon nanotubes (CNTs).

May

Finding real rewards in a virtual world

by adam phillips | Hot Off the Press

A new study shows that mice who learn to find goals in virtual reality use their hippocampus the same was as in the real world.

Apr

RIKEN is looking for you

by adam phillips | What's Up With Us

RIKEN is looking for you. Check out our new introductory videos! learn about exotic nuclei and much much more.

Apr

Promising mouse model for Ngly1 deficiency

by adam phillips | Hot Off the Press

A recent study of Ngly1 deficient mice used a secondary knockout to create double knockouts with symptoms similar to human NGLY1 deficiency.

Apr

Nihonium walk of fame

by jens wilkinson | Drop of science, What's Up With Us

A nihonium walk of fame is being built to commemorate the discovery of the 113th element

Apr

New rice fights off drought

by adam phillips | Hot Off the Press

Researchers have created drought resistant transgenic rice using a gene from a small Eurasian flowering plant

Apr

Centennial RIKEN Research

by adam phillips | Hot Off the Press

???This Spring we’ve put together a special centennial issue of RIKEN Research ???

Mar

Don’t know anything about RIKEN?

by adam phillips | What's Up With Us

Don’t know anything about RIKEN? We’ve made a new RIKEN booklet that should help!

Jan

Blocking obesity with a protein-sugar combination

by adam phillips | Hot Off the Press

Discovery of an enzyme that prevents obesity in mice through glycosylation of a protein involved fat-cell differentiation.

Dec

Robotic researcher to the rescue

by kylius wilkins | Drop of science, Interviews

Masaki Watabe talks about automated robotic researchers, future robot rule, and scientific philosophy.

Quick, call Spiderman: scientists discover how spider silk is formed

A group of scientists led by researchers have discovered a key mechanism through which spider silk is formed.

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RIKEN at a glance

We’ve just gotten our order of RIKEN at a Glance booklets back from the printers, and they look fantastic. Follow the link to download your electronic copy now!

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The free-energy principle explains neural network behavior

Scientists show that the free-energy principle can explain how neural networks work.

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The sound of molecules: NMR-inspired music

Science & art: how NMR works and how NMR spectra have been used to compose music based on molecular structures.

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Ultraprecise clocks and the Tokyo Skytree verify Einstein’s theory of relativity

Time measured at the top and bottom of the Tokyo Skytree with ultraprecise clocks has verified the time dilation effect predicted by Einstein.

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Massive filaments, galaxies, and supermassive black holes

Big telescopes yield big data! Detailed observations gas filaments connecting galaxies in a distant proto-cluster in the early Universe.

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Mar

Telework: a societal game-changer

by jens wilkinson | Interviews

COVID-19 series — installment #3: Team Leader Osamu Sakura (@RIKEN Center for Advanced Intelligence Project) talks about how the pandemic has affected society through the need for telework.

Mar

Decision-making during the COVID-19 pandemic

by jens wilkinson | Interviews

COVID-19 series — installment #2: RIKEN CBS Unit Leader Rei Akaishi talks about government decision-making during the pandemic.

Mar

Confronting a string of epidemics including COVID-19

by jens wilkinson | Interviews

COVID-19 series — installment #1: RIKEN Executive Director Shigeo Koyasu talks about epidemics and what a good response looks like.

Feb

Next stop: clinical hair regeneration

by adam phillips | Featured, Hot Off the Press

A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.

Jan

Godzilla-sized zooplankton for better aquafarming

by masataka sasabe | Hot Off the Press

Scientists have created extra large zooplankton to help feed the fish in aquafarms. The new plankton were created using an ion beam to generate mutations.

Dec

Electric rays to help us map the ocean floor

by adam phillips | Hot Off the Press

Electric rays and sting rays could map the ocean floor through their natural behavior, helping us find resources and collect data on other ocean life.

Nov

Bacterial drug resistance studied by robotic E. coli evolution

by masataka sasabe | Hot Off the Press

Experimentally evolving E. coli under pressure from a large number of antibiotics was able to identify constraints underlying evolved drug resistance.

Nov

New artificial skin helps avoid animal testing

by masataka sasabe | Hot Off the Press

A new artificial skin that reproduces proper tension can be used to research skin function and disease while reducing the need to experiment on animals.

Oct

Social novelty in the brain: haven’t I seen you someplace before?

by adam phillips | Hot Off the Press

Social novelty and contextual novelty are segregated in the SuM region of the hypothalamus and in projections to the hippocampus, allowing memories of meeting new people to be formed separately from memories of new places.

H2AK119ub1: How you inherit acquired traits from your mom

H2AK119ub1. Say that three times really fast! But seriously, it allows maternally acquired traits to be inherited.

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Artificial gravity protects the immune system of mice in space

Mice who experienced artificial gravity on the ISS suffered less damage to their immune system (thymus) than weightless mice did.

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How does gravity affect antimatter?

Scientists find that antimatter reacts to gravity the same way that regular matter does.

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Social contact-seeking behavior and loneliness in the brain

Levels of the peptide amylin in the brain are related to loneliness; activating amylin neurons in the MPOA drives isolated mice to seek social contact.

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Sep

A faster and more sensitive antibody test for COVID-19

by masataka sasabe | Hot Off the Press

Fast and sensitive: A new antibody test for the COVID-19 virus. Just a pinprick of blood and results in 30 minutes.

Continue!

Jul

Opossums are the first genome edited marsupials

by masataka sasabe | Featured, Hot Off the Press

A new piezoelectronic microinjection method has allowed the first successful genome editing in marsupials: albino opossums.

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Jul

Methylation mutation directly linked to autism

by adam phillips | Hot Off the Press

A mutation in a gene needed for H3K9 methylation is directly linked to autism spectrum disorders and early neurodevelopment.

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Jun

Melatonin in mice, circadian rhythms, and daily torpor

by amanda alvarez | Hot Off the Press

A new breed of lab mouse allows the study of naturally occurring melatonin. These mice will adjust better to jetlag than regular lab mice and experience daily torpor.

Continue!

Jun