The It Ain't Magic Science Blog

Next stop: clinical hair regeneration

A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.

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Artificial gravity protects the immune system of mice in space

Mice who experienced artificial gravity on the ISS suffered less damage to their immune system (thymus) than weightless mice did.

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Gray matter volume links symptoms in autism

Low gray matter volume in the posterior superior parietal lobule (pSPL) was found to correlate with specific cognitive and perceptual symptoms of autism.

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Boosting betaine may be a treatment for schizophrenia

Supplementing model mice with glycine betaine (trimethylglycine), a compound originally derived from beets, can alleviate symptoms of schizophrenia.

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FABP4: A preschool-aged biomarker for autism

Reduced FABP4 was found in preschool-aged children with autism spectrum disorder, making it a potential new biomarker for the condition.

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Smarter AI: machine learning without negative data

Scientists have developed a new method for machine learning that allows an AI to make better classifications without negative data.

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Topics

Latest research animations

NEW: Opossum hearts hint at new ways of fighting cardiovascular disease

Artificial intelligence improves the diagnosis of congenital heart defects before birth

Full research highlight animation playlist (click the menu icon to see video list)

Latest Posts

Jul

Eating a high fat diet without getting obese?

by adam phillips | Featured, Hot Off the Press

Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.

Jul

New metalloenzyme system selectively targets cancer cells

by masataka sasabe | Hot Off the Press

Specific targeting of cancer cells and onsite drug synthesis has been achieved using a new artificial metalloenzyme delivery system.

Jun

Boosting betaine may be a treatment for schizophrenia

by amanda alvarez | Hot Off the Press

Supplementing model mice with glycine betaine (trimethylglycine), a compound originally derived from beets, can alleviate symptoms of schizophrenia.

Jun

Gray matter volume links symptoms in autism

by adam phillips | Hot Off the Press

Low gray matter volume in the posterior superior parietal lobule (pSPL) was found to correlate with specific cognitive and perceptual symptoms of autism.

Jun

New mechanism allows lower energy requirement for OLED displays

by jens wilkinson | Hot Off the Press

Scientists have found a way to significantly reduce the amount of energy required by organic light emitting diodes (OLED) displays.

Jun

CAPON links Alzheimer’s plaques to neurodegeneration

by adam phillips | Hot Off the Press

CAPON was found to link Aβ plaques and hippocampal neurodegeneration in mice, explaining how these two hallmarks of Alzheimer’s disease are related.

May

AdR blockers protect the brain from stroke damage

by amanda alvarez | Hot Off the Press

Treatment with adrenergic receptor antagonists (AdR blockers) was able to reduce stroke-related brain damage in mice and improve motor recovery.

Apr

Trigger region found for epileptic absence seizures

by adam phillips | Hot Off the Press

A mouse model shows that absence seizures are triggered by faulty connections between the cortex and fast-spiking neurons in the striatum.

Apr

Opto-OISI: imaging connections in the living brain

by amanda alvarez | Hot Off the Press

A new imaging technique called opto-OISI allows scientists to non-invasively visualize where specific neurons project in the living brain.

Apr

Flies smell through a gore-tex system

by masataka sasabe | Hot Off the Press

The newly named gore-tex gene is responsible for the development of nanopores that allow chemicals in the air to be detected (in flies).

Apr

Protein pileup affects social behavior through altered brain signaling

by amanda alvarez | Hot Off the Press

When a normal cellular cleanup process is disrupted, social behavior in mice is disrupted and they start behaving in ways that resemble human symptoms of autism spectrum disorder and schizophrenia.

Mar

The joys of computational mass spectrometry

by adam phillips | Hot Off the Press

Scientists have developed a new automated computational mass spectrometry system that can search an organism’s entire metabolome for as-yet-unknown metabolites (potential drugs).

Mar

Pulses of light can enhance superconductivity

by jens wilkinson | Hot Off the Press

Pulses of light could be used to turn materials into superconductors through an unconventional type of superconductivity.

Feb

Scientists create new type of self-healing material

by jens wilkinson | Hot Off the Press

This newly created ethylene-based material has shape memory that allows self-healing!

Feb

Brain clock ticks differently in autism

by amanda alvarez | Hot Off the Press

A new brain imaging study shows that autistic severity is linked to how long certain regions of the brain store information.

Dec

Supermassive black holes still dark and mysterious

by jens wilkinson | Hot Off the Press

For the first time, scientists have measured the strength of magnetic fields near supermassive black holes and something doesn’t add up.

Dec

Evolution of the inner ear: insights from jawless fish

by adam phillips | Hot Off the Press

A new story for inner ear evolution based on the developmental patterning found in hagfish, one of two extant jawless vertebrates and a link to the last common ancestor of modern jawed vertebrates.

Dec

Tumor detection during breast cancer surgery

by jens wilkinson | Hot Off the Press

Scientists have developed a new way to accurately detect the margins between cancerous and non-cancerous tissue during breast cancer surgery.

Nov

Smarter AI: machine learning without negative data

by masataka sasabe | Hot Off the Press

Scientists have developed a new method for machine learning that allows an AI to make better classifications without negative data.

Nov

Nerdnite recap: When the brainbow met the boson

by amanda alvarez | Drop of science

Fun times at nerdnite tokyo. Brains, bosons, and math, oh my!

Nov

Mutations, CRISPR, and spinocerebellar ataxia

by adam phillips | Hot Off the Press

Scientists discover that mutations causing the degenerative movement disorder spinocerebellar ataxia type 29 work by disrupting calcium release of neurons inside the brain.

Nov

Gene regulator that allows plant rehydration after drought

by adam phillips | Hot Off the Press

New genetic insights into the plant rehydration process: this is why your plants don’t die after you forgot to water them.

Oct

Researchers create a functional salivary gland organoid ?

by jens wilkinson | Hot Off the Press

Scientists have succeeded in growing three-dimensional salivary gland tissue that produced saliva like normal glands when implanted into mice.

Oct

Getting a grip on slow but unique shark evolution

by masataka sasabe | Hot Off the Press

Scientists have decoded the genomes of two species of shark, bringing the grand total of sequenced shark genomes to three.

Oct

Ig Nobel awards: Silly experiments that strike gold

by amanda alvarez | Drop of science

Amanda writes about the Ig Nobel awards after founder Marc Abrahams visited nerdnite Tokyo. Science at its best!

Oct

A self-powered heart monitor taped to the skin

by jens wilkinson | Hot Off the Press

A group of scientists have developed a human-friendly, ultra-flexible organic sensor powered by sunlight, which acts as a self-powered heart monitor.

Sep

Protostars that exhibit large diversity in organic compounds

by riken research highlights | Research Highlight

A survey of a molecular cloud has found that the organic chemical makeup of protostars varies considerably.

Sep

Scientists solve epigenetic barriers to cloning

by jens wilkinson | Hot Off the Press

Scientists show that two epigenetic factors improve the success rate of cloning via somatic cell nuclear transfer.

Aug

Transgenic plants 🌱🌿on acid survive without water

by adam phillips | Featured, Research Highlight

Scientists designed transgenic plants that survive drought-like conditions by bumping up acetic acid production only when water is scarce.

Aug

Two genes that regulate how much we dream

by masataka sasabe | Hot Off the Press

An international research team led by RIKEN BDR has identified a pair of genes that regulate how much REM (dream) and non-REM sleep an animal experiences.

Aug

Flies use fecal deposits as pheromones

by amanda alvarez | Hot Off the Press

Bioluminescence imaging of fly brains reveals neurons sensitive to fly poo laced with pheromones (you can see the fecal “landmark” in the dotted circle). Need we say more?

Jul

Hippocampal memory isn’t all about place cells

by amanda alvarez | Hot Off the Press

Scientists have found evidence that hippocampal memories of experience are not stored in place cells.

Jul

Summer fun: how plants beat the heat

by adam phillips | Hot Off the Press

Scientists have discovered a gene that allows plants to cope with extreme heat by changing the composition of chloroplast membranes.

Jun

Freedom from fear ?‍♀️

by adam phillips | Hot Off the Press

Researchers discover a dopaminergic circuit in the brain that allows fear associations to disappear when there isn’t anything to be afraid of anymore.

Jun

Blue gene regulation helps plants respond properly to light

by adam phillips | Hot Off the Press

Blue light alters some gene expression in plants by changing the transcription start sites to downstream locations.

Jun

Out on a limb: the many ‘brains’ of the octopus

by amanda alvarez | Drop of science

Learn how (neurologically) cool octopus arms are (as if you didn’t already know).

Jun

Mutation links bipolar disorder to mitochondrial disease

by amanda alvarez | Hot Off the Press

ANT1 mutations found in bipolar disease that affect mitochondria lead to hyperexcitable serotonergic neuronal activity in the brain.

Jun

My science communication journey in Tokyo

by sarah naimi | What's Up With Us

New contributor and nuclear physicist Sarah Naimi talks about her recent experience in science communication at a recent scicom event in Tokyo.

Jun

Gene linked to intellectual ability affects memory replay in mice

by adam phillips | Hot Off the Press

Scientists have discovered a gene in mice that allows memory replay at rest, a process necessary for forming long-lasting memories in mice.

Centennial RIKEN Research

???This Spring we’ve put together a special centennial issue of RIKEN Research ???

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Memories are made of this 🎶 🎷 – (Part 1)

Brain science ’round midnight episode 8: Thomas McHugh from the RIKEN Center for Brain Science discusses memories and the brain

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Are you “at risk” of being a habitual coffee drinker?

Several single nucleotide polymorphisms (SNPs) are related to dietary habits, including coffee, tea, tofu, and yogurt consumption.

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Flies smell through a gore-tex system

The newly named gore-tex gene is responsible for the development of nanopores that allow chemicals in the air to be detected (in flies).

Read on

Clean and green: a moss that removes lead (Pb) from water

Scientists show that the moss Funaria hygrometrica can remove harmful lead from water when in the protonema stage of development.

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Social novelty in the brain: haven’t I seen you someplace before?

Social novelty and contextual novelty are segregated in the SuM region of the hypothalamus and in projections to the hippocampus, allowing memories of meeting new people to be formed separately from memories of new places.

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Feb

Nanocarrier spray: better crops without genetic modification

by adam phillips | Hot Off the Press

Gene expression, but not genomes, altered in plants and crops with a spray containing bioactive molecules tethered to nanocarrier peptides

Feb

Introducing Nikola, the emotional android boy

by adam phillips | Featured, Hot Off the Press

A new android named Nikola will help researchers study facial expressions, emotions, and social interactions.

Feb

Green hydrogen production for fuel cells and fertilizers

by adam phillips | Featured, Hot Off the Press

A new method of water electrolysis avoids rare metals, making hydrogen production green and sustainable.

Feb

Social contact-seeking behavior and loneliness in the brain

by adam phillips | Featured, Hot Off the Press

Levels of the peptide amylin in the brain are related to loneliness; activating amylin neurons in the MPOA drives isolated mice to seek social contact.

Feb

New treatment assembles cancer drug inside the body

by masataka sasabe | Featured, Hot Off the Press

Cancer drugs assembled inside the body on cancer cells should reduce harmful side effects to other tissue.

Jan

New lab-grown retinal sheets almost ready for clinical trials

by adam phillips | Featured, Hot Off the Press

A new retinal transplant technique works by preventing bipolar cells from maturing in lab-grown retinal sheets.

Jan

The free-energy principle explains neural network behavior

by adam phillips | Hot Off the Press

Scientists show that the free-energy principle can explain how neural networks work.

Jan

How does gravity affect antimatter?

by jens wilkinson | Featured, Hot Off the Press

Scientists find that antimatter reacts to gravity the same way that regular matter does.

Dec

Super-thin wearable electronics just got more flexible

by adam phillips | Featured, Hot Off the Press

A method for making super-flexible and ultra-thin wearable electronics uses water-vapor plasma to create gold-gold bonds.

New lab-grown retinal sheets almost ready for clinical trials

A new retinal transplant technique works by preventing bipolar cells from maturing in lab-grown retinal sheets.

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Super-thin wearable electronics just got more flexible

A method for making super-flexible and ultra-thin wearable electronics uses water-vapor plasma to create gold-gold bonds.

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Talking science Illustration with Misaki Ouchida

Whether it’s bird anatomy or science cartoons, Masaki Ouchida can do it all. She spoke with us about her career in science illustration, from the US to Japan.

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Eating a high fat diet without getting obese?

Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.

Read on

May

Palaeospondylus: mystery of vertebrate evolution solved

by adam phillips | Hot Off the Press

Micro-CT scans using synchrotron radiation X-rays reveal Palaeospondylus morphology, finally allowing its placement on the evolutionary tree.

Continue!

Apr

Xist knockout rescues miscarriages in mice

by adam phillips | Hot Off the Press

Xist knockout rescues miscarriages in mice whose egg cells lack H3K27me3 epigenetic instructions.

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Apr

A new type of cell death discovered in fly guts

by masataka sasabe | Hot Off the Press

A completely unknown type of cell death called “erebosis” has been discovered in the guts of the common fruit fly.

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Apr

Diagnosing fetal heart disease benefits from explanatory AI

by adam phillips | Hot Off the Press

Diagnosis accuracy improved when doctors used explanatory AI to help diagnose congenital heart disease from fetal ultrasound videos.

Continue!

Apr

Chaos theory provides hints for controlling the weather

by jens wilkinson | Hot Off the Press

Computer simulations were used to show that small adjustments to certain variables in the weather system could modify weather phenomena such as sudden downpours.

Continue!

Mar