The It Ain't Magic Science Blog

New metalloenzyme system selectively targets cancer cells

Specific targeting of cancer cells and onsite drug synthesis has been achieved using a new artificial metalloenzyme delivery system.

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Cancer cells killed with artificial glycosylated metalloenzyme

Scientists have developed two cancer therapies that use an artificial glycosylated metalloenzyme to specifically target cancer cells in mice.

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Engineering crop immunity from a receptor in pomelo fruit

Synthetic receptors derived from the pomelo fruit can help crops become immune to thousands of pathogens.

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Big news in iPS cell transplants

iPS cell-derived retinal cells have been successfully transplanted from one monkey to another without need of immunosuppressant drugs.

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Researchers create a functional salivary gland organoid ?

Scientists have succeeded in growing three-dimensional salivary gland tissue that produced saliva like normal glands when implanted into mice.

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Something smells fishy: categorizing odors in the brain

Calcium imaging and mathematical model explain how categories and mixtures of odors are represented in the fly brain and consistent across individual flies.

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Self-assembly of spider silk

This gut microbe might protect against diabetes and reduce insulin resistance

NEW: One-way hydrogel guides motion of tiny worms!

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Centennial RIKEN Research

???This Spring we’ve put together a special centennial issue of RIKEN Research ???

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Plant peptide spells relief from salty stress

Newly discovered plant peptide hormone can be used to protect plants from excessive environmental salt.

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Robotic AI helps efficient growth of replacement organs

Humans team-up with a robotic AI to speed up experiments to find the best way to regrow damaged eye tissue from stem cells.

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Next stop: clinical hair regeneration

A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.

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Learning and unlearning to fear: The two faces of noradrenaline

Fear association and unlearning fear association require different populations of noradrenaline neurons in the locus coeruleus.

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Xist knockout rescues miscarriages in mice

Xist knockout rescues miscarriages in mice whose egg cells lack H3K27me3 epigenetic instructions.

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Jun

Blue gene regulation helps plants respond properly to light

by adam phillips | Hot Off the Press

Blue light alters some gene expression in plants by changing the transcription start sites to downstream locations.

Jun

Out on a limb: the many ‘brains’ of the octopus

by admin | Drop of science

Learn how (neurologically) cool octopus arms are (as if you didn’t already know).

Jun

Mutation links bipolar disorder to mitochondrial disease

by admin | Hot Off the Press

ANT1 mutations found in bipolar disease that affect mitochondria lead to hyperexcitable serotonergic neuronal activity in the brain.

Jun

My science communication journey in Tokyo

by admin | What's Up With Us

New contributor and nuclear physicist Sarah Naimi talks about her recent experience in science communication at a recent scicom event in Tokyo.

Jun

Gene linked to intellectual ability affects memory replay in mice

by adam phillips | Hot Off the Press

Scientists have discovered a gene in mice that allows memory replay at rest, a process necessary for forming long-lasting memories in mice.

May

Quick, call Spiderman: scientists discover how spider silk is formed

by jens wilkinson | Hot Off the Press

A group of scientists led by researchers have discovered a key mechanism through which spider silk is formed.

May

Mutation protects against Alzheimer’s disease in mice

by adam phillips | Hot Off the Press

Scientists discover a deletion mutation that reduces amyloid-beta plaque formation in Alzheimer’s disease model mice.

May

Plant peptide spells relief from salty stress

by adam phillips | Hot Off the Press

Newly discovered plant peptide hormone can be used to protect plants from excessive environmental salt.

May

Putting E. coli to work for us

by riken research highlights | Research Highlight

Specially engineered bacteria can produce an industrially significant chemical from renewable sources in a much gentler process than the one currently used by industry.

Next stop: clinical hair regeneration

A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.

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New lab-grown retinal sheets almost ready for clinical trials

A new retinal transplant technique works by preventing bipolar cells from maturing in lab-grown retinal sheets.

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Talking science Illustration with Misaki Ouchida

Whether it’s bird anatomy or science cartoons, Masaki Ouchida can do it all. She spoke with us about her career in science illustration, from the US to Japan.

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Artificial gravity protects the immune system of mice in space

Mice who experienced artificial gravity on the ISS suffered less damage to their immune system (thymus) than weightless mice did.

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May

A new imaging biomarker for the aging brain

by adam phillips | Hot Off the Press

Enlarged ventricles is a sign of an aging brain. New research shows that this phenomenon can be predicted by lagging brain circulation that is detected by MRI.