The It Ain't Magic Science Blog

The brain’s GPS has a buddy system

In addition to encoding self location, brain cells in the rat hippocampus act like a GPS that encodes the location of other rats.

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Hibernation-like state can protect kidneys during heart surgery

Activating Q-neurons in the mouse brain led to a hibernation-like state that protected kidneys during heart surgery.

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Skipping fatty acids could be recipe for schizophrenia

Prenatal lack of omega-3 and omega-6 fatty acids linked to epigenetic changes that lead to schizophrenic symptoms in mice.

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Random movements help color-detecting cells form the proper pattern

Scientists have used a mathematical model to explain why zebrafish cone cells in the eye are arranged in a specific pattern in all individuals.

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Cassava engineered to produce healthier tapioca starch

Reducing the amount of starch branching enzymes in cassava plants made more resistant and thus healthier tapioca starch.

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Albumin drops medicine off at cancer site then leaves the body

By changing albumin’s identity, drugs can carried to their targets and then removed from the body after being used.

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Latest research animations

Self-assembly of spider silk

This gut microbe might protect against diabetes and reduce insulin resistance

NEW: One-way hydrogel guides motion of tiny worms!

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Boosting betaine may be a treatment for schizophrenia

Supplementing model mice with glycine betaine (trimethylglycine), a compound originally derived from beets, can alleviate symptoms of schizophrenia.

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Mutation protects against Alzheimer’s disease in mice

Scientists discover a deletion mutation that reduces amyloid-beta plaque formation in Alzheimer’s disease model mice.

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Mutation links bipolar disorder to mitochondrial disease

ANT1 mutations found in bipolar disease that affect mitochondria lead to hyperexcitable serotonergic neuronal activity in the brain.

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From evolutionary morphology to Godzilla

I recently spoke with RIKEN scientist Shigeru Kuratani about evolutionary morphology, sci-fi monsters, the genius of Alien, and more.

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Tumor detection during breast cancer surgery

Scientists have developed a new way to accurately detect the margins between cancerous and non-cancerous tissue during breast cancer surgery.

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Cyborg microchip valve driven by earthworm muscle

This earthworm muscle-controlled biological microelectromechanical system (bio‐MEMS) could lead the way to next-generation medical implants.

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Jun

Melatonin in mice, circadian rhythms, and daily torpor

by amanda alvarez | Hot Off the Press

A new breed of lab mouse allows the study of naturally occurring melatonin. These mice will adjust better to jetlag than regular lab mice and experience daily torpor.

Apr

Cancer cells killed with artificial glycosylated metalloenzyme

by adam phillips | Hot Off the Press

Scientists have developed two cancer therapies that use an artificial glycosylated metalloenzyme to specifically target cancer cells in mice.

Mar

Telework: a societal game-changer

by jens wilkinson | Interviews

COVID-19 series — installment #3: Team Leader Osamu Sakura (@RIKEN Center for Advanced Intelligence Project) talks about how the pandemic has affected society through the need for telework.

Jun

Why (mouse) mothers take risks to protect their infants

by adam phillips | Featured, Hot Off the Press

The calcitonin receptor and its ligand amylin act in the brain to motivate mouse mothers to protect their pups, even in risky/dangerous situations.

Apr

H2AK119ub1: How you inherit acquired traits from your mom

by adam phillips | Featured, Hot Off the Press

H2AK119ub1. Say that three times really fast! But seriously, it allows maternally acquired traits to be inherited.

Mar

Decision-making during the COVID-19 pandemic

by jens wilkinson | Interviews

COVID-19 series — installment #2: RIKEN CBS Unit Leader Rei Akaishi talks about government decision-making during the pandemic.

May

Dietary amino acid linked to cancer in flies

by masataka sasabe | Hot Off the Press

Researchers have found a dietary amino acid linked to oncogene expression / tumor formation; reduced consumption reduced cancer in flies.

Apr

COVID-19: Changing the way we do research

by jens wilkinson | Interviews

COVID-19 series — Part #4: Team Leader Aki Minoda from RIKEN IMS talks about how the pandemic has affected the way we work.

Mar

Confronting a string of epidemics including COVID-19

by jens wilkinson | Interviews

COVID-19 series — installment #1: RIKEN Executive Director Shigeo Koyasu talks about epidemics and what a good response looks like.

New lab-grown retinal sheets almost ready for clinical trials

A new retinal transplant technique works by preventing bipolar cells from maturing in lab-grown retinal sheets.

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Talking science Illustration with Misaki Ouchida

Whether it’s bird anatomy or science cartoons, Masaki Ouchida can do it all. She spoke with us about her career in science illustration, from the US to Japan.