The It Ain't Magic Science Blog

RIKEN Research Fall Issue

Fall is here, and with it comes the latest issue of RIKEN Research. This issue covers tactile learning during sleep, supercomputers and simulations, solar cells, fly olfaction, tumor vaccines, and more

RIKEN Research Winter Issue

It’s almost the end of the year and a here’s an early holiday present! The winter issue of RIKEN Research is here, covering plant parasites, depression, atomic clocks, and more! Enjoy!

In living color: imaging the brain with synthetic bioluminescence

A new way to image the brain from outside the head using bioluminescence.

Brain clock ticks differently in autism

A new brain imaging study shows that autistic severity is linked to how long certain regions of the brain store information.

Blocking obesity with a protein-sugar combination

Discovery of an enzyme that prevents obesity in mice through glycosylation of a protein involved fat-cell differentiation.

Xist knockout rescues miscarriages in mice

Xist knockout rescues miscarriages in mice whose egg cells lack H3K27me3 epigenetic instructions.

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Latest research animations

Self-assembly of spider silk

This gut microbe might protect against diabetes and reduce insulin resistance

NEW: One-way hydrogel guides motion of tiny worms!

Latest Posts

6

Stable green hydrogen production in a PEM electrolyzer

Stable green hydrogen production in a PEM electrolyzer

by adam phillips | Hot Off the Press

A little structurally manipulated manganese goes a long way when using a PEM electrolyzer to make hydrogen from water.

24

Brainless memory makes the spinal cord smarter than previously thought

Brainless memory makes the spinal cord smarter than previously thought

by adam phillips | Hot Off the Press

The spinal cord learns how to direct limb muscles to avoid aversive sensations and recalls the memories using separate neural circuitry. Oh, and without a brain!

22

Eco-friendly ammonia production for fertilizers and alternative fuel

Eco-friendly ammonia production for fertilizers and alternative fuel

by adam phillips | Hot Off the Press

A new process that allows ammonia to be produced using much less energy than the standard methods.

11

Cubes of brain tissue allow drug discovery without animals

Cubes of brain tissue allow drug discovery without animals

by masataka sasabe | Hot Off the Press

Modeling the blood-brain-barrier with brains-in-a-cube allows drug testing without the need for animals.

3

Gut bacteria could help overcome milk allergy

Gut bacteria could help overcome milk allergy

by adam phillips | Hot Off the Press

Analysis shows that some gut bacteria could help improve oral immunotherapy against milk allergy.

2

Detecting pathogens: the evolution of plant immunity

Detecting pathogens: the evolution of plant immunity

by masataka sasabe | Hot Off the Press

Scientists find recognition receptors for plant growth and plant immunity that share a common evolutionary origin.

21

Genomic “butterfly effect” involving TADs explains risk for autism

Genomic “butterfly effect” involving TADs explains risk for autism

by masataka sasabe | Hot Off the Press

De novo mutations in three-dimensional structures in the genome containing known ASD genes were found to be associated with ASD risk.

19

Heat used to transform antiskyrmions to skyrmions and back

Heat used to transform antiskyrmions to skyrmions and back

by jens wilkinson | Hot Off the Press

Scientists discover a way to transform antiskyrmions to skyrmions and back using heat and magnetic fields.

23

Real webshooters? Synthetic spider silk spun from artificial gland

Real webshooters? Synthetic spider silk spun from artificial gland

by adam phillips | Hot Off the Press

Scientists create a microfluidic device that spins artificial spider silk from spidroins proteins, duplicating silk’s complex molecular structure.

15

Omics Omics Omics: Analysis predicts ovarian cancer-treating drug

Omics Omics Omics: Analysis predicts ovarian cancer-treating drug

by adam phillips | Hot Off the Press

Multi-omics analysis prediction: drugs that inhibit Ras signaling will help prevent tumor formation in serous ovarian cancer.

27

First hydride-ion battery that works at room temperature

First hydride-ion battery that works at room temperature

by adam phillips | Hot Off the Press

Researchers develop a new solid electrolyte that can conduct hydride ions, thus allowing better hydrogen-based batteries and fuel cells.

10

Plants to the rescue: cleaning up our dirty soil

Plants to the rescue: cleaning up our dirty soil

by adam phillips | Drop of science

A brief review of phytoremediation and research into how plants can be used to clean the environment.

1

Stolen genes used for parasitic mind control

Stolen genes used for parasitic mind control

by masataka sasabe | Hot Off the Press

Parasitic horsehair worms evolved to control their praying mantis hosts by stealing their genes (horizontal gene transfer).

27

Machine learning contributes to better quantum error correction

Machine learning contributes to better quantum error correction

by jens wilkinson | Hot Off the Press

Researchers have developed an autonomous method for handling error correction in quantum computing. This will help quantum computers maintain their advantages over standard computers.

20

Laser melting ice-core sampler for studying climate change

Laser melting ice-core sampler for studying climate change

by adam phillips | Hot Off the Press

This laser melting ice core sampler can determine temperature changes thousands of years ago on very fine timescale.

31

Gut bacteria reduces insulin resistance, protects against diabetes

Gut bacteria reduces insulin resistance, protects against diabetes

by adam phillips | Hot Off the Press

Scientists discover gut bacteria that reduce insulin resistance in your body and sugar in your poo.

23

Scary places burned into our minds by constant memory replay

Scary places burned into our minds by constant memory replay

by riken research highlights | Research Highlight

Researchers discover the mechanism through which places associated with negative experiences are burned into our memories.

18

Toward human hibernation: cold-resistant mouse stem cells

Toward human hibernation: cold-resistant mouse stem cells

by adam phillips | Hot Off the Press

Cold-resistant stem cells from “deep torpor” mice are a big step toward understanding why tissue survives hibernation.

15

A researcher’s journey part 2: emotional memory and being human

A researcher’s journey part 2: emotional memory and being human

by adam phillips | Interviews

Joshua Johansen from RIKEN CBS explains emotional memory, what his lab is doing, and what makes a good researcher.

8

Mathematical model predicts self-organized learning in real neurons

Mathematical model predicts self-organized learning in real neurons

by adam phillips | Hot Off the Press

The free energy principle predicted how real neural connections changed as neurons “learned” in a dish.

7

Deadly fungi beaten with fatty acid synthase inhibitor

Deadly fungi beaten with fatty acid synthase inhibitor

by adam phillips | Hot Off the Press

A new approach to attacking fungi involves inhibiting a gene needed for making fatty acids.

12

A new and improved way to store hydrogen

A new and improved way to store hydrogen

by masataka sasabe | Hot Off the Press

A simple chemical reaction allows hydrogen-carrying ammonia to be stored and retrieved cheaply and easily.

29

A new alpha-particle treatment for multiple cancers

A new alpha-particle treatment for multiple cancers

by adam phillips | Hot Off the Press

A new type of alpha-particle therapy allows selective targeting of tumors in multiple cancers.

28

A researcher’s journey: from surfing to studying pain

A researcher’s journey: from surfing to studying pain

by adam phillips | Interviews

Joshua Johansen from RIKEN CBS tells us about his journey from surfer to pain researcher and beyond. Stay tuned for part II …

15

The first drug treatment for brain aneurysms (in mice)

The first drug treatment for brain aneurysms (in mice)

by adam phillips | Hot Off the Press

Scientists discover that most aneurysms result from mutations. A mouse model shows they can be treated with drugs.

12

Simple but revolutionary modular organoids

Simple but revolutionary modular organoids

by jens wilkinson | Hot Off the Press

A new way to construct complex 3D organoids without using elaborate techniques! The trick using modular cubes with hydrogel layers.

19

Thoughts on the genetics of medicinal licorice

Thoughts on the genetics of medicinal licorice

by jens wilkinson | Drop of science

Jens talks about licorice and a recent RIKEN study that finally mapped its genome.

24

Pathogenic genetic variation linked to H. pylori-related stomach cancer

Pathogenic genetic variation linked to H. pylori-related stomach cancer

by adam phillips | Hot Off the Press

Researchers find that the risk of stomach cancer due to infection withH. Pylori bacteria increases with specific genetic variations.

29

ERRg predicts atrial fibrillation and hidden comorbidity

ERRg predicts atrial fibrillation and hidden comorbidity

by adam phillips | Hot Off the Press

Polygenic risk scores based on the genetic data from more that a million people predicted atrial fibrillation, stroke, and mortality.

27

Memories are made of this ?? – (Part 2)

Memories are made of this ?? – (Part 2)

by adam phillips | Interviews

Thomas McHugh from the RIKEN Center for Brain Science continues his discussion about memories, emotions, the brain, and life.

26

Replicating opossum heart regeneration to help fight cardiovascular disease

Replicating opossum heart regeneration to help fight cardiovascular disease

by adam phillips | Research Animation

Animated research highlight: Opossum hearts hint at new ways of fighting cardiovascular disease

26

Spacey, nerdy nights in Tokyo

Spacey, nerdy nights in Tokyo

by kelly jackson | What's Up With Us

Kelly, our new It Ain’t Magic contributor, writes about her nerdy nighttime experiences in Tokyo.

16

Memories are made of this ? ? – (Part 1)

Memories are made of this ? ? – (Part 1)

by adam phillips | Interviews

Brain science ’round midnight episode 8: Thomas McHugh from the RIKEN Center for Brain Science discusses memories and the brain

18

Hibernation-like state can protect kidneys during heart surgery

Hibernation-like state can protect kidneys during heart surgery

by adam phillips | Hot Off the Press

Activating Q-neurons in the mouse brain led to a hibernation-like state that protected kidneys during heart surgery.

14

Crying baby? Science says walk, then sit

Crying baby? Science says walk, then sit

by adam phillips | Hot Off the Press

Recipe for success: Walk 5 min, sit 8 min, lay no-longer-crying baby down. Now you can relax.

6

Cyborg cockroaches to the rescue!

Cyborg cockroaches to the rescue!

by masataka sasabe | Hot Off the Press

The key to this remote-controllable cyborg cockroach is a solar-cell rechargeable battery and an ultrathin flexible backpack.

25

Ethanol pretreated soil protects plants from drought

Ethanol pretreated soil protects plants from drought

by adam phillips | Hot Off the Press

Pretreating soil with ethanol protected plants, including wheat and rice, from the adverse effects of water deprivation.

22

Marsupial heart regeneration ability given to mice

Marsupial heart regeneration ability given to mice

by adam phillips | Hot Off the Press

Regeneration of mouse hearts ? ?? after birth achieved by figuring out how it’s possible in opossums.

19

How an herbal medicine protects against inflamed bowels

How an herbal medicine protects against inflamed bowels

by adam phillips | Hot Off the Press

A Japanese herbal medicine promotes good bacteria and innate immune cells in the gut, which protects against intestinal inflammation.

Mutations, CRISPR, and spinocerebellar ataxia

Scientists discover that mutations causing the degenerative movement disorder spinocerebellar ataxia type 29 work by disrupting calcium release of neurons inside the brain.

Palaeospondylus: mystery of vertebrate evolution solved

Micro-CT scans using synchrotron radiation X-rays reveal Palaeospondylus morphology, finally allowing its placement on the evolutionary tree.

AdR blockers protect the brain from stroke damage

Treatment with adrenergic receptor antagonists (AdR blockers) was able to reduce stroke-related brain damage in mice and improve motor recovery.

Scientists create new type of self-healing material

This newly created ethylene-based material has shape memory that allows self-healing!

Researchers create a functional salivary gland organoid ?

Scientists have succeeded in growing three-dimensional salivary gland tissue that produced saliva like normal glands when implanted into mice.

Proton and antiproton still seem identical

Using a novel two-particle measurement method, scientists have measured the magnetic moment of the antiproton at a precision 350 times higher than any previous measurement.

6

Stable green hydrogen production in a PEM electrolyzer

Stable green hydrogen production in a PEM electrolyzer

by adam phillips | Hot Off the Press

A little structurally manipulated manganese goes a long way when using a PEM electrolyzer to make hydrogen from water.

24

Brainless memory makes the spinal cord smarter than previously thought

Brainless memory makes the spinal cord smarter than previously thought

by adam phillips | Hot Off the Press

The spinal cord learns how to direct limb muscles to avoid aversive sensations and recalls the memories using separate neural circuitry. Oh, and without a brain!

22

Eco-friendly ammonia production for fertilizers and alternative fuel

Eco-friendly ammonia production for fertilizers and alternative fuel

by adam phillips | Hot Off the Press

A new process that allows ammonia to be produced using much less energy than the standard methods.

11

Cubes of brain tissue allow drug discovery without animals

Cubes of brain tissue allow drug discovery without animals

by masataka sasabe | Hot Off the Press

Modeling the blood-brain-barrier with brains-in-a-cube allows drug testing without the need for animals.

3

Gut bacteria could help overcome milk allergy

Gut bacteria could help overcome milk allergy

by adam phillips | Hot Off the Press

Analysis shows that some gut bacteria could help improve oral immunotherapy against milk allergy.

2

Detecting pathogens: the evolution of plant immunity

Detecting pathogens: the evolution of plant immunity

by masataka sasabe | Hot Off the Press

Scientists find recognition receptors for plant growth and plant immunity that share a common evolutionary origin.

21

Genomic “butterfly effect” involving TADs explains risk for autism

Genomic “butterfly effect” involving TADs explains risk for autism

by masataka sasabe | Hot Off the Press

De novo mutations in three-dimensional structures in the genome containing known ASD genes were found to be associated with ASD risk.

19

Heat used to transform antiskyrmions to skyrmions and back

Heat used to transform antiskyrmions to skyrmions and back

by jens wilkinson | Hot Off the Press

Scientists discover a way to transform antiskyrmions to skyrmions and back using heat and magnetic fields.

23

Real webshooters? Synthetic spider silk spun from artificial gland

Real webshooters? Synthetic spider silk spun from artificial gland

by adam phillips | Hot Off the Press

Scientists create a microfluidic device that spins artificial spider silk from spidroins proteins, duplicating silk’s complex molecular structure.

Green hydrogen production for fuel cells and fertilizers

A new method of water electrolysis avoids rare metals, making hydrogen production green and sustainable.

Next stop: clinical hair regeneration

A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.

Talking science Illustration with Misaki Ouchida

Whether it’s bird anatomy or science cartoons, Masaki Ouchida can do it all. She spoke with us about her career in science illustration, from the US to Japan.

Electrolithoautotrophs

Learn what electrolithoautotrophs are and how the scientists proved that A. ferrooxidans can use electric potential to fuel growth.

6

Stable green hydrogen production in a PEM electrolyzer

Stable green hydrogen production in a PEM electrolyzer

by adam phillips | Hot Off the Press

A little structurally manipulated manganese goes a long way when using a PEM electrolyzer to make hydrogen from water.

24

Brainless memory makes the spinal cord smarter than previously thought

Brainless memory makes the spinal cord smarter than previously thought

by adam phillips | Hot Off the Press

The spinal cord learns how to direct limb muscles to avoid aversive sensations and recalls the memories using separate neural circuitry. Oh, and without a brain!

22

Eco-friendly ammonia production for fertilizers and alternative fuel

Eco-friendly ammonia production for fertilizers and alternative fuel

by adam phillips | Hot Off the Press

A new process that allows ammonia to be produced using much less energy than the standard methods.

11

Cubes of brain tissue allow drug discovery without animals

Cubes of brain tissue allow drug discovery without animals

by masataka sasabe | Hot Off the Press

Modeling the blood-brain-barrier with brains-in-a-cube allows drug testing without the need for animals.

3

Gut bacteria could help overcome milk allergy

Gut bacteria could help overcome milk allergy

by adam phillips | Hot Off the Press

Analysis shows that some gut bacteria could help improve oral immunotherapy against milk allergy.

2

Detecting pathogens: the evolution of plant immunity

Detecting pathogens: the evolution of plant immunity

by masataka sasabe | Hot Off the Press

Scientists find recognition receptors for plant growth and plant immunity that share a common evolutionary origin.