The It Ain't Magic Science Blog

RIKEN at a glance

We’ve just gotten our order of RIKEN at a Glance booklets back from the printers, and they look fantastic. Follow the link to download your electronic copy now!

RIKEN Research Summer issue

A quick post to let you know that the Summer issue of RIKEN Research Magazine came out towards the end of June. This issue covers brain evolution, regenerating skin, super-clear synapses, and much much more! Enjoy!

Stable green hydrogen production in a PEM electrolyzer

A little structurally manipulated manganese goes a long way when using a PEM electrolyzer to make hydrogen from water.

Locating social memories in the brain

Scientists have identified where social memories are stored in the brains of mice. Mice are forgotten because memories cannot be retrieved.

New metalloenzyme system selectively targets cancer cells

Specific targeting of cancer cells and onsite drug synthesis has been achieved using a new artificial metalloenzyme delivery system.

Supermassive black holes still dark and mysterious

For the first time, scientists have measured the strength of magnetic fields near supermassive black holes and something doesn’t add up.

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Latest research animations

Self-assembly of spider silk

This gut microbe might protect against diabetes and reduce insulin resistance

NEW: One-way hydrogel guides motion of tiny worms!

Latest Posts

May

26

Dietary amino acid linked to cancer in flies

Dietary amino acid linked to cancer in flies

by masataka sasabe | Hot Off the Press

Researchers have found a dietary amino acid linked to oncogene expression / tumor formation; reduced consumption reduced cancer in flies.

Apr

30

Cancer cells killed with artificial glycosylated metalloenzyme

Cancer cells killed with artificial glycosylated metalloenzyme

by adam phillips | Hot Off the Press

Scientists have developed two cancer therapies that use an artificial glycosylated metalloenzyme to specifically target cancer cells in mice.

Apr

9

H2AK119ub1: How you inherit acquired traits from your mom

H2AK119ub1: How you inherit acquired traits from your mom

by adam phillips | Featured, Hot Off the Press

H2AK119ub1. Say that three times really fast! But seriously, it allows maternally acquired traits to be inherited.

Apr

8

COVID-19: Changing the way we do research

COVID-19: Changing the way we do research

by jens wilkinson | Interviews

COVID-19 series — Part #4: Team Leader Aki Minoda from RIKEN IMS talks about how the pandemic has affected the way we work.

Mar

26

Telework: a societal game-changer

Telework: a societal game-changer

by jens wilkinson | Interviews

COVID-19 series — installment #3: Team Leader Osamu Sakura (@RIKEN Center for Advanced Intelligence Project) talks about how the pandemic has affected society through the need for telework.

Mar

18

Decision-making during the COVID-19 pandemic

Decision-making during the COVID-19 pandemic

by jens wilkinson | Interviews

COVID-19 series — installment #2: RIKEN CBS Unit Leader Rei Akaishi talks about government decision-making during the pandemic.

Mar

5

Confronting a string of epidemics including COVID-19

Confronting a string of epidemics including COVID-19

by jens wilkinson | Interviews

COVID-19 series — installment #1: RIKEN Executive Director Shigeo Koyasu talks about epidemics and what a good response looks like.

Feb

19

Next stop: clinical hair regeneration

Next stop: clinical hair regeneration

by adam phillips | Featured, Hot Off the Press

A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.

Jan

22

Godzilla-sized zooplankton for better aquafarming

Godzilla-sized zooplankton for better aquafarming

by masataka sasabe | Hot Off the Press

Scientists have created extra large zooplankton to help feed the fish in aquafarms. The new plankton were created using an ion beam to generate mutations.

Dec

10

Electric rays to help us map the ocean floor

Electric rays to help us map the ocean floor

by adam phillips | Hot Off the Press

Electric rays and sting rays could map the ocean floor through their natural behavior, helping us find resources and collect data on other ocean life.

Nov

26

Bacterial drug resistance studied by robotic E. coli evolution

Bacterial drug resistance studied by robotic E. coli evolution

by masataka sasabe | Hot Off the Press

Experimentally evolving E. coli under pressure from a large number of antibiotics was able to identify constraints underlying evolved drug resistance.

Nov

9

New artificial skin helps avoid animal testing

New artificial skin helps avoid animal testing

by masataka sasabe | Hot Off the Press

A new artificial skin that reproduces proper tension can be used to research skin function and disease while reducing the need to experiment on animals.

Oct

2

Social novelty in the brain: haven’t I seen you someplace before?

Social novelty in the brain: haven’t I seen you someplace before?

by adam phillips | Hot Off the Press

Social novelty and contextual novelty are segregated in the SuM region of the hypothalamus and in projections to the hippocampus, allowing memories of meeting new people to be formed separately from memories of new places.

Sep

11

FABP4: A preschool-aged biomarker for autism

FABP4: A preschool-aged biomarker for autism

by adam phillips | Hot Off the Press

Reduced FABP4 was found in preschool-aged children with autism spectrum disorder, making it a potential new biomarker for the condition.

Sep

3

Microbial infections are a parasitic plant’s dream

Microbial infections are a parasitic plant’s dream

by adam phillips | Hot Off the Press

Parasitic plants use quinones produced by their host to attack. Now we know that crops produce quinones as an immune response against microbial infection. How can we protect crops from both kinds of attack?

Aug

27

Gut bacteria double team worsens symptoms of multiple sclerosis

Gut bacteria double team worsens symptoms of multiple sclerosis

by adam phillips | Hot Off the Press

Joint activity of two gut bacteria leads to excessive MOG-specific T-cell activity and demyelination of neurons in the spinal cord of a mouse model of multiple sclerosis.

Aug

19

Something smells fishy: categorizing odors in the brain

Something smells fishy: categorizing odors in the brain

by masataka sasabe | Hot Off the Press

Calcium imaging and mathematical model explain how categories and mixtures of odors are represented in the fly brain and consistent across individual flies.

Jul

8

Photosynthetic bacteria spin spider silk for the masses

Photosynthetic bacteria spin spider silk for the masses

by masataka sasabe | Hot Off the Press

A little genetic engineering and a special recipe allows photosynthetic bacteria to mass-produce super lightweight spider silk for use in manufacturing.

Jun

25

Blood cell mutations linked to leukemia are inevitable

Blood cell mutations linked to leukemia are inevitable

by adam phillips | Hot Off the Press

Researchers show that blood cell mutations increase with age identify risk factors for developing leukemia in Japanese and European populations.

Jun

10

Organic nitrogen in soil helps crop growth

Organic nitrogen in soil helps crop growth

by jens wilkinson | Hot Off the Press

Scientists used a multi-omics analysis to show that soil solarization helps crops grow because it increases organic nitrogen in the soil.

May

12

Consciousness, brain connections, and the claustrum

Consciousness, brain connections, and the claustrum

by amanda alvarez | Hot Off the Press

Research shows that the claustrum acts as a ‘consciousness conductor’ that synchronizes and connects areas within the mouse brain.

May

7

A new imaging biomarker for the aging brain

A new imaging biomarker for the aging brain

by adam phillips | Hot Off the Press

Enlarged ventricles is a sign of an aging brain. New research shows that this phenomenon can be predicted by lagging brain circulation that is detected by MRI.

Apr

29

Sphingolipid S1P: Potential new target for schizophrenia treatment

Sphingolipid S1P: Potential new target for schizophrenia treatment

by adam phillips | Hot Off the Press

Sphingolipid S1P is reduced in brain white matter of people with schizophrenia, making S1P receptors a good target for new treatments.

Apr

27

Staining that lights up whole organs and bodies

Staining that lights up whole organs and bodies

by masataka sasabe | Hot Off the Press

Scientists have developed a staining procedure that makes see-through tissue, organs, and bodies useful.

Apr

23

Artificial gravity protects the immune system of mice in space

Artificial gravity protects the immune system of mice in space

by adam phillips | Featured, Research News

Mice who experienced artificial gravity on the ISS suffered less damage to their immune system (thymus) than weightless mice did.

Apr

14

Ultraprecise clocks and the Tokyo Skytree verify Einstein’s theory of relativity

Ultraprecise clocks and the Tokyo Skytree verify Einstein’s theory of relativity

by jens wilkinson | Hot Off the Press

Time measured at the top and bottom of the Tokyo Skytree with ultraprecise clocks has verified the time dilation effect predicted by Einstein.

Mar

20

Low-protein diet changes sperm and health of future offspring

Low-protein diet changes sperm and health of future offspring

by masataka sasabe | Hot Off the Press

Low-protein diets in male mice alter sperm and result in offspring that have metabolic problems like diabetes in adulthood.

Mar

13

Physiological origami and proper body development in flies

Physiological origami and proper body development in flies

by masataka sasabe | Hot Off the Press

Genetics and mechanical origami in the fly embryo helps proper body development by fighting off “noisy” fluctuations is the environment.

Mar

11

Efficient and durable ultra-thin solar cells

Efficient and durable ultra-thin solar cells

by jens wilkinson | Hot Off the Press

Ultra-thin, flexible, organic solar cells that degrade less than 5 percent after 3,000 hours and an energy conversion ratio of 13%.

Mar

9

Tape and vermilion: ingredients for mapping artifact origins

Tape and vermilion: ingredients for mapping artifact origins

by adam phillips | Hot Off the Press

Vermilion samples taken from ancient artifacts with sulfur-free tape can tell us about trade patterns 3000 years ago.

Jan

29

Are you “at risk” of being a habitual coffee drinker?

Are you “at risk” of being a habitual coffee drinker?

by adam phillips | Hot Off the Press

Several single nucleotide polymorphisms (SNPs) are related to dietary habits, including coffee, tea, tofu, and yogurt consumption.

Jan

24

Astrocytes powered by norepinephrine during fear-memory formation

Astrocytes powered by norepinephrine during fear-memory formation

by amanda alvarez | Hot Off the Press

Norepinephrine released in the locus coeruleus during fear learning is accompanied by increased calcium and cAMP levels in nearby astrocytes.

Dec

19

Brain wave synchrony can predict memory age

Brain wave synchrony can predict memory age

by amanda alvarez | Hot Off the Press

The degree of neuronal synchrony between the anterior cingulate cortex and the hippocampus during recall is an indication of memory age (in mice).

Dec

18

AI identifies features associated with cancer recurrence

AI identifies features associated with cancer recurrence

by masataka sasabe | Hot Off the Press

Artificial intelligence has successfully identified features relevant to cancer prognosis that were not previously noted by pathologists

Nov

15

Longevity in supercentenarians linked to cytotoxic T-cells

Longevity in supercentenarians linked to cytotoxic T-cells

by jens wilkinson | Hot Off the Press

Blood analysis in supercentenarians showed that they have many more cytotoxic CD4 T-cells than people with average life spans.

Oct

29

Schizophrenia biomarker (hydrogen sulfide) in human hair

Schizophrenia biomarker (hydrogen sulfide) in human hair

by adam phillips | Hot Off the Press

Not only is hydrogen sulfide a good biomarker for schizophrenia, it’s also the culprit and a new starting point for drug discovery.

Oct

10

Brain tissue kept alive for weeks with new microfluidic device

Brain tissue kept alive for weeks with new microfluidic device

by adam phillips | Hot Off the Press

A new microfluidic device can keep tissue cultures functional for weeks on an artificial membrane

Oct

4

Massive filaments, galaxies, and supermassive black holes

Massive filaments, galaxies, and supermassive black holes

by jens wilkinson | Hot Off the Press

Big telescopes yield big data! Detailed observations gas filaments connecting galaxies in a distant proto-cluster in the early Universe.

Oct

3

Understanding non-coding DNA: gene “enhancers”

Understanding non-coding DNA: gene “enhancers”

by jens wilkinson | Hot Off the Press

NETCAGE is a newly developed technique for determining the structure of portions of the non-coding genome called ‘enhancers.’

Geostationary satellite enables better precipitation and flood predictions

Data from the Himawari-8 geosynchronous satellite was used in weather simulations to improve forecasts of sudden precipitation and tropical storm development.

Pulses of light can enhance superconductivity

Pulses of light could be used to turn materials into superconductors through an unconventional type of superconductivity.

Flies smell through a gore-tex system

The newly named gore-tex gene is responsible for the development of nanopores that allow chemicals in the air to be detected (in flies).

CAPON links Alzheimer’s plaques to neurodegeneration

CAPON was found to link Aβ plaques and hippocampal neurodegeneration in mice, explaining how these two hallmarks of Alzheimer’s disease are related.

Dietary amino acid linked to cancer in flies

Researchers have found a dietary amino acid linked to oncogene expression / tumor formation; reduced consumption reduced cancer in flies.

Blocking obesity with a protein-sugar combination

Discovery of an enzyme that prevents obesity in mice through glycosylation of a protein involved fat-cell differentiation.

Apr

2

Detecting pathogens: the evolution of plant immunity

Detecting pathogens: the evolution of plant immunity

by masataka sasabe | Hot Off the Press

Scientists find recognition receptors for plant growth and plant immunity that share a common evolutionary origin.

Mar

21

Genomic “butterfly effect” involving TADs explains risk for autism

Genomic “butterfly effect” involving TADs explains risk for autism

by masataka sasabe | Hot Off the Press

De novo mutations in three-dimensional structures in the genome containing known ASD genes were found to be associated with ASD risk.

Mar

19

Heat used to transform antiskyrmions to skyrmions and back

Heat used to transform antiskyrmions to skyrmions and back

by jens wilkinson | Hot Off the Press

Scientists discover a way to transform antiskyrmions to skyrmions and back using heat and magnetic fields.

Jan

23

Real webshooters? Synthetic spider silk spun from artificial gland

Real webshooters? Synthetic spider silk spun from artificial gland

by adam phillips | Hot Off the Press

Scientists create a microfluidic device that spins artificial spider silk from spidroins proteins, duplicating silk’s complex molecular structure.

Jan

15

Omics Omics Omics: Analysis predicts ovarian cancer-treating drug

Omics Omics Omics: Analysis predicts ovarian cancer-treating drug

by adam phillips | Hot Off the Press

Multi-omics analysis prediction: drugs that inhibit Ras signaling will help prevent tumor formation in serous ovarian cancer.

Dec

27

First hydride-ion battery that works at room temperature

First hydride-ion battery that works at room temperature

by adam phillips | Hot Off the Press

Researchers develop a new solid electrolyte that can conduct hydride ions, thus allowing better hydrogen-based batteries and fuel cells.

Nov

10

Plants to the rescue: cleaning up our dirty soil

Plants to the rescue: cleaning up our dirty soil

by adam phillips | Drop of science

A brief review of phytoremediation and research into how plants can be used to clean the environment.

Nov

1

Stolen genes used for parasitic mind control

Stolen genes used for parasitic mind control

by masataka sasabe | Hot Off the Press

Parasitic horsehair worms evolved to control their praying mantis hosts by stealing their genes (horizontal gene transfer).

Sep

27

Machine learning contributes to better quantum error correction

Machine learning contributes to better quantum error correction

by jens wilkinson | Hot Off the Press

Researchers have developed an autonomous method for handling error correction in quantum computing. This will help quantum computers maintain their advantages over standard computers.

Green hydrogen production for fuel cells and fertilizers

A new method of water electrolysis avoids rare metals, making hydrogen production green and sustainable.

Next stop: clinical hair regeneration

A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.

How does gravity affect antimatter?

Scientists find that antimatter reacts to gravity the same way that regular matter does.

New lab-grown retinal sheets almost ready for clinical trials

A new retinal transplant technique works by preventing bipolar cells from maturing in lab-grown retinal sheets.

May

10

Recipe for hydrogen: sprinkle manganese oxide with iridium atoms, add water

Recipe for hydrogen: sprinkle manganese oxide with iridium atoms, add water

by adam phillips | Hot Off the Press

A few iridium atoms also go a long way. When sprinkled on manganese oxide, hydrogen is produced with 95% less iridium!

May

6

Stable green hydrogen production in a PEM electrolyzer

Stable green hydrogen production in a PEM electrolyzer

by adam phillips | Hot Off the Press

A little structurally manipulated manganese goes a long way when using a PEM electrolyzer to make hydrogen from water.

Apr

24

Brainless memory makes the spinal cord smarter than previously thought

Brainless memory makes the spinal cord smarter than previously thought

by adam phillips | Hot Off the Press

The spinal cord learns how to direct limb muscles to avoid aversive sensations and recalls the memories using separate neural circuitry. Oh, and without a brain!

Apr

22

Eco-friendly ammonia production for fertilizers and alternative fuel

Eco-friendly ammonia production for fertilizers and alternative fuel

by adam phillips | Hot Off the Press

A new process that allows ammonia to be produced using much less energy than the standard methods.

Apr

11

Cubes of brain tissue allow drug discovery without animals

Cubes of brain tissue allow drug discovery without animals

by masataka sasabe | Hot Off the Press

Modeling the blood-brain-barrier with brains-in-a-cube allows drug testing without the need for animals.

Apr

3

Gut bacteria could help overcome milk allergy

Gut bacteria could help overcome milk allergy

by adam phillips | Hot Off the Press

Analysis shows that some gut bacteria could help improve oral immunotherapy against milk allergy.