The It Ain't Magic Science Blog

Smarter AI: machine learning without negative data

Scientists have developed a new method for machine learning that allows an AI to make better classifications without negative data.

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Physiological origami and proper body development in flies

Genetics and mechanical origami in the fly embryo helps proper body development by fighting off “noisy” fluctuations is the environment.

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Deep-brain exploration with nanomaterials

A new way to optogenetically activate neurons deep in the brain using infrared light and upconversion nanoparticles. It’s non-invasive!

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Gray matter volume links symptoms in autism

Low gray matter volume in the posterior superior parietal lobule (pSPL) was found to correlate with specific cognitive and perceptual symptoms of autism.

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Mutation links bipolar disorder to mitochondrial disease

ANT1 mutations found in bipolar disease that affect mitochondria lead to hyperexcitable serotonergic neuronal activity in the brain.

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Memory retrieval needs a neuronal connecting flight

Scientists use optogenetics to discover a part of the brain necessary for retrieving memories of personal experiences.

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Topics

Latest research animations

Self-assembly of spider silk

This gut microbe might protect against diabetes and reduce insulin resistance

NEW: One-way hydrogel guides motion of tiny worms!

Latest Posts

Nov

Microcolumns: elementary neuronal units that carpet the (mouse) brain

by amanda alvarez | Hot Off the Press

A hexagonal lattice organizes major cell types in the cerebral cortex, with similar cells synchronizing their activity in microcolumns.

Oct

Jupiter’s volcano-powered auroral lights

by riken research highlights | Research Highlight

A collaborative effort used data from NASA’s Juno spacecraft to explain the transient auroras found on Jupiter.

Oct

Hepatoma (liver cancer) blocked by a sugar look-a-like

by adam phillips | Hot Off the Press

A sugar (fucose) analog can prevent liver cancer (hepatoma) from invading healthy liver cells.

Oct

Random movements help color-detecting cells form the proper pattern

by jens wilkinson | Hot Off the Press

Scientists have used a mathematical model to explain why zebrafish cone cells in the eye are arranged in a specific pattern in all individuals.

Sep

Visualizing chick-brain morphogenesis

by riken research highlights | Research Highlight

A new statistical-based method provides insight into the morphogenesis of developing organs.

Sep

Skin-like wearable electronics

by riken research highlights | Research Highlight

Sensors made from stretchable nanomesh allow skin to breathe naturally while continuously monitoring patient health.

Sep

Solar cells you can put in the wash

by jens wilkinson | Hot Off the Press

Scientists have developed ultra-thin photovoltaic solar cells that can be incorporated into fabric and even washed.

Sep

Learning and unlearning to fear: The two faces of noradrenaline

by adam phillips | Hot Off the Press

Fear association and unlearning fear association require different populations of noradrenaline neurons in the locus coeruleus.

Sep

ּּּBigger oocytes = more mistakes

by riken research highlights | Research Highlight

The large size of mouse oocytes is shown to create errors when chromosomes divide between daughter cells.

Sep

Superfly flight simulator helps unravel navigation in the brain

by adam phillips | Hot Off the Press

Optical imaging neural activity in flies as they use a flight simulator can help us understand how the brain codes navigation.

Sep

Skipping fatty acids could be recipe for schizophrenia

by adam phillips | Hot Off the Press

Prenatal lack of omega-3 and omega-6 fatty acids linked to epigenetic changes that lead to schizophrenic symptoms in mice.

Aug

A gut-wrenching defense against parasitic worms

by riken research highlights | Research Highlight

Mast cells in the gut help fight off parasitic worms in the early stages of infection.

Aug

Memory retrieval needs a neuronal connecting flight

by adam phillips | Hot Off the Press

Scientists use optogenetics to discover a part of the brain necessary for retrieving memories of personal experiences.

Aug

From egg to embryo

by riken research highlights | Research Highlight

A newly discovered gene turns off an egg’s egginess, allowing it to become an embryo.

Aug

This nickel catalyst bats from both sides of the plate

by riken research highlights | Research Highlight

Scientists discover that a nickel catalyst acts as both a acid and a base during molecule assembly.

Jul

New info about how chromosomes form

by riken research highlights | Research Highlight

Fewer components are needed for chromosome assembly during cell division than previously supposed.

Jul

Tracking how stars grow up in a virtual playground

by amanda alvarez | Research Highlight

Amanda Alvarez writes about Steven Rieder and his research in modeling clusters of growing new stars.

Jul

Protons are lighter than previously thought

by jens wilkinson | Hot Off the Press

A new and most precise measurement of protons shows that they are lighter than previously thought.

Jul

Untangling depression in Huntington’s disease

by riken research highlights | Research Highlight

New research implicates clumps of insoluble, misfolded proteins in the development of mental illness in people with Huntington’s disease

Jul

Imaging whole-body cancer metastasis at the single-cell level

by adam phillips | Hot Off the Press

A new optical clearing method allows imaging of cancer metastasis at incredibly high resolution.

Jun

Meet the editors: the growing pains of scientific publishing

by amanda alvarez | What's Up With Us

Amanda Alvarez writes about the recent seminars at RIKEN by Philip Campbell and Emilie Marcus, the editors-in-chief of Nature and Cell.

May

Carbon nanotubes, what are they good for?

by kylius wilkins | Interviews, What's Up With Us

Kylius Wilkins talks to Urs Frey and his recent success manufacturing carbon nanotubes (CNTs).

May

Finding real rewards in a virtual world

by adam phillips | Hot Off the Press

A new study shows that mice who learn to find goals in virtual reality use their hippocampus the same was as in the real world.

Apr

RIKEN is looking for you

by adam phillips | What's Up With Us

RIKEN is looking for you. Check out our new introductory videos! learn about exotic nuclei and much much more.

Apr

Promising mouse model for Ngly1 deficiency

by adam phillips | Hot Off the Press

A recent study of Ngly1 deficient mice used a secondary knockout to create double knockouts with symptoms similar to human NGLY1 deficiency.

Apr

Nihonium walk of fame

by jens wilkinson | Drop of science, What's Up With Us

A nihonium walk of fame is being built to commemorate the discovery of the 113th element

Apr

New rice fights off drought

by adam phillips | Hot Off the Press

Researchers have created drought resistant transgenic rice using a gene from a small Eurasian flowering plant

Apr

Centennial RIKEN Research

by adam phillips | Hot Off the Press

???This Spring we’ve put together a special centennial issue of RIKEN Research ???

Mar

Don’t know anything about RIKEN?

by adam phillips | What's Up With Us

Don’t know anything about RIKEN? We’ve made a new RIKEN booklet that should help!

Jan

Blocking obesity with a protein-sugar combination

by adam phillips | Hot Off the Press

Discovery of an enzyme that prevents obesity in mice through glycosylation of a protein involved fat-cell differentiation.

Dec

Robotic researcher to the rescue

by kylius wilkins | Drop of science, Interviews

Masaki Watabe talks about automated robotic researchers, future robot rule, and scientific philosophy.

Dec

RIKEN Research Winter Issue

by adam phillips | Hot Off the Press

It’s almost the end of the year and a here’s an early holiday present! The winter issue of RIKEN Research is here, covering plant parasites, depression, atomic clocks, and more! Enjoy!

Dec

The geometry of consciousness is a multi-dimensional math trip

by amanda alvarez | Research Highlight

Amanda Alvarez writes about how neuroscientists are studying consciousness with mathematics

Oct

Fall is here, and with it comes the latest issue of RIKEN Research. This issue covers tactile learning during sleep, supercomputers and simulations, solar cells, fly olfaction, tumor vaccines, and more

Sep

Locating social memories in the brain

by adam phillips | Hot Off the Press

Scientists have identified where social memories are stored in the brains of mice. Mice are forgotten because memories cannot be retrieved.

Sep

Big news in iPS cell transplants

by adam phillips | Hot Off the Press

iPS cell-derived retinal cells have been successfully transplanted from one monkey to another without need of immunosuppressant drugs.

Aug

In Japan, women in science seek allies, resources in push for gender equality

by amanda alvarez | What's Up With Us

neuroamanda talks about gender equality for female scientists is Japan.

Aug

Measuring altitude — with clocks?

by jens wilkinson | Drop of science

Measuring altitude using atomic clocks seems like a crazy idea, but it’s already being done at RIKEN in Japan

Aug

The sound of molecules: NMR-inspired music

by adam phillips | Research in Depth, Science Heavy

Science & art: how NMR works and how NMR spectra have been used to compose music based on molecular structures.

Quick, call Spiderman: scientists discover how spider silk is formed

A group of scientists led by researchers have discovered a key mechanism through which spider silk is formed.

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Longevity in supercentenarians linked to cytotoxic T-cells

Blood analysis in supercentenarians showed that they have many more cytotoxic CD4 T-cells than people with average life spans.

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Sphingolipid S1P: Potential new target for schizophrenia treatment

Sphingolipid S1P is reduced in brain white matter of people with schizophrenia, making S1P receptors a good target for new treatments.

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Protein antigens in meat, milk, and other foods suppress gut tumors

Food antigens were found to prevent small intestinal tumors in gut-tumor prone mice by making ensuring we have enough T cells for defense.

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Learning and unlearning to fear: The two faces of noradrenaline

Fear association and unlearning fear association require different populations of noradrenaline neurons in the locus coeruleus.

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Nanocarrier spray: better crops without genetic modification

Gene expression, but not genomes, altered in plants and crops with a spray containing bioactive molecules tethered to nanocarrier peptides

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Aug

Mathematical model predicts self-organized learning in real neurons

by adam phillips | Hot Off the Press

The free energy principle predicted how real neural connections changed as neurons “learned” in a dish.

Aug

Deadly fungi beaten with fatty acid synthase inhibitor

by adam phillips | Hot Off the Press

A new approach to attacking fungi involves inhibiting a gene needed for making fatty acids.

Jul

A new and improved way to store hydrogen

by masataka sasabe | Hot Off the Press

A simple chemical reaction allows hydrogen-carrying ammonia to be stored and retrieved cheaply and easily.

Jun

A new alpha-particle treatment for multiple cancers

by adam phillips | Hot Off the Press

A new type of alpha-particle therapy allows selective targeting of tumors in multiple cancers.

Jun

A researcher’s journey: from surfing to studying pain

by adam phillips | Interviews

Joshua Johansen from RIKEN CBS tells us about his journey from surfer to pain researcher and beyond. Stay tuned for part II …

Jun

The first drug treatment for brain aneurysms (in mice)

by adam phillips | Hot Off the Press

Scientists discover that most aneurysms result from mutations. A mouse model shows they can be treated with drugs.

Jun

Simple but revolutionary modular organoids

by jens wilkinson | Hot Off the Press

A new way to construct complex 3D organoids without using elaborate techniques! The trick using modular cubes with hydrogel layers.

May

Thoughts on the genetics of medicinal licorice

by jens wilkinson | Drop of science

Jens talks about licorice and a recent RIKEN study that finally mapped its genome.

Apr

Pathogenic genetic variation linked to H. pylori-related stomach cancer

by adam phillips | Hot Off the Press

Researchers find that the risk of stomach cancer due to infection withH. Pylori bacteria increases with specific genetic variations.

Next stop: clinical hair regeneration

A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.

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Talking science Illustration with Misaki Ouchida

Whether it’s bird anatomy or science cartoons, Masaki Ouchida can do it all. She spoke with us about her career in science illustration, from the US to Japan.