The It Ain't Magic Science Blog

From evolutionary morphology to Godzilla

I recently spoke with RIKEN scientist Shigeru Kuratani about evolutionary morphology, sci-fi monsters, the genius of Alien, and more.

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Decision-making during the COVID-19 pandemic

COVID-19 series — installment #2: RIKEN CBS Unit Leader Rei Akaishi talks about government decision-making during the pandemic.

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Smarter AI: machine learning without negative data

Scientists have developed a new method for machine learning that allows an AI to make better classifications without negative data.

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Diazoxide pills for Alzheimer’s disease?

Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.

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FABP4: A preschool-aged biomarker for autism

Reduced FABP4 was found in preschool-aged children with autism spectrum disorder, making it a potential new biomarker for the condition.

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Social contact-seeking behavior and loneliness in the brain

Levels of the peptide amylin in the brain are related to loneliness; activating amylin neurons in the MPOA drives isolated mice to seek social contact.

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Latest research animations

Self-assembly of spider silk

This gut microbe might protect against diabetes and reduce insulin resistance

NEW: One-way hydrogel guides motion of tiny worms!

Latest Posts

Nov

Microcolumns: elementary neuronal units that carpet the (mouse) brain

by admin | Hot Off the Press

A hexagonal lattice organizes major cell types in the cerebral cortex, with similar cells synchronizing their activity in microcolumns.

Oct

Jupiter’s volcano-powered auroral lights

by riken research highlights | Research Highlight

A collaborative effort used data from NASA’s Juno spacecraft to explain the transient auroras found on Jupiter.

Oct

Hepatoma (liver cancer) blocked by a sugar look-a-like

by adam phillips | Hot Off the Press

A sugar (fucose) analog can prevent liver cancer (hepatoma) from invading healthy liver cells.

Oct

Random movements help color-detecting cells form the proper pattern

by jens wilkinson | Hot Off the Press

Scientists have used a mathematical model to explain why zebrafish cone cells in the eye are arranged in a specific pattern in all individuals.

Sep

Visualizing chick-brain morphogenesis

by riken research highlights | Research Highlight

A new statistical-based method provides insight into the morphogenesis of developing organs.

Sep

Skin-like wearable electronics

by riken research highlights | Research Highlight

Sensors made from stretchable nanomesh allow skin to breathe naturally while continuously monitoring patient health.

Sep

Solar cells you can put in the wash

by jens wilkinson | Hot Off the Press

Scientists have developed ultra-thin photovoltaic solar cells that can be incorporated into fabric and even washed.

Sep

Learning and unlearning to fear: The two faces of noradrenaline

by adam phillips | Hot Off the Press

Fear association and unlearning fear association require different populations of noradrenaline neurons in the locus coeruleus.

Sep

ּּּBigger oocytes = more mistakes

by riken research highlights | Research Highlight

The large size of mouse oocytes is shown to create errors when chromosomes divide between daughter cells.

Sep

Superfly flight simulator helps unravel navigation in the brain

by adam phillips | Hot Off the Press

Optical imaging neural activity in flies as they use a flight simulator can help us understand how the brain codes navigation.

Sep

Skipping fatty acids could be recipe for schizophrenia

by adam phillips | Hot Off the Press

Prenatal lack of omega-3 and omega-6 fatty acids linked to epigenetic changes that lead to schizophrenic symptoms in mice.

Aug

A gut-wrenching defense against parasitic worms

by riken research highlights | Research Highlight

Mast cells in the gut help fight off parasitic worms in the early stages of infection.

Aug

Memory retrieval needs a neuronal connecting flight

by adam phillips | Hot Off the Press

Scientists use optogenetics to discover a part of the brain necessary for retrieving memories of personal experiences.

Aug

From egg to embryo

by riken research highlights | Research Highlight

A newly discovered gene turns off an egg’s egginess, allowing it to become an embryo.

Aug

This nickel catalyst bats from both sides of the plate

by riken research highlights | Research Highlight

Scientists discover that a nickel catalyst acts as both a acid and a base during molecule assembly.

Jul

New info about how chromosomes form

by riken research highlights | Research Highlight

Fewer components are needed for chromosome assembly during cell division than previously supposed.

Jul

Tracking how stars grow up in a virtual playground

by admin | Research Highlight

Amanda Alvarez writes about Steven Rieder and his research in modeling clusters of growing new stars.

Jul

Protons are lighter than previously thought

by jens wilkinson | Hot Off the Press

A new and most precise measurement of protons shows that they are lighter than previously thought.

Jul

Untangling depression in Huntington’s disease

by riken research highlights | Research Highlight

New research implicates clumps of insoluble, misfolded proteins in the development of mental illness in people with Huntington’s disease

Jul

Imaging whole-body cancer metastasis at the single-cell level

by adam phillips | Hot Off the Press

A new optical clearing method allows imaging of cancer metastasis at incredibly high resolution.

Jun

Meet the editors: the growing pains of scientific publishing

by admin | What's Up With Us

Amanda Alvarez writes about the recent seminars at RIKEN by Philip Campbell and Emilie Marcus, the editors-in-chief of Nature and Cell.

May

Carbon nanotubes, what are they good for?

by admin | Interviews, What's Up With Us

Kylius Wilkins talks to Urs Frey and his recent success manufacturing carbon nanotubes (CNTs).

May

Finding real rewards in a virtual world

by adam phillips | Hot Off the Press

A new study shows that mice who learn to find goals in virtual reality use their hippocampus the same was as in the real world.

Apr

RIKEN is looking for you

by adam phillips | What's Up With Us

RIKEN is looking for you. Check out our new introductory videos! learn about exotic nuclei and much much more.

Apr

Promising mouse model for Ngly1 deficiency

by adam phillips | Hot Off the Press

A recent study of Ngly1 deficient mice used a secondary knockout to create double knockouts with symptoms similar to human NGLY1 deficiency.

Apr

Nihonium walk of fame

by jens wilkinson | Drop of science, What's Up With Us

A nihonium walk of fame is being built to commemorate the discovery of the 113th element

Apr

New rice fights off drought

by adam phillips | Hot Off the Press

Researchers have created drought resistant transgenic rice using a gene from a small Eurasian flowering plant

Apr

Centennial RIKEN Research

by adam phillips | Hot Off the Press

???This Spring we’ve put together a special centennial issue of RIKEN Research ???

Mar

Don’t know anything about RIKEN?

by adam phillips | What's Up With Us

Don’t know anything about RIKEN? We’ve made a new RIKEN booklet that should help!

Jan

Blocking obesity with a protein-sugar combination

by adam phillips | Hot Off the Press

Discovery of an enzyme that prevents obesity in mice through glycosylation of a protein involved fat-cell differentiation.

Dec

Robotic researcher to the rescue

by admin | Drop of science, Interviews

Masaki Watabe talks about automated robotic researchers, future robot rule, and scientific philosophy.

Dec

RIKEN Research Winter Issue

by adam phillips | Hot Off the Press

It’s almost the end of the year and a here’s an early holiday present! The winter issue of RIKEN Research is here, covering plant parasites, depression, atomic clocks, and more! Enjoy!

Dec

The geometry of consciousness is a multi-dimensional math trip

by admin | Research Highlight

Amanda Alvarez writes about how neuroscientists are studying consciousness with mathematics

Oct

Fall is here, and with it comes the latest issue of RIKEN Research. This issue covers tactile learning during sleep, supercomputers and simulations, solar cells, fly olfaction, tumor vaccines, and more

Sep

Locating social memories in the brain

by adam phillips | Hot Off the Press

Scientists have identified where social memories are stored in the brains of mice. Mice are forgotten because memories cannot be retrieved.

Sep

Big news in iPS cell transplants

by adam phillips | Hot Off the Press

iPS cell-derived retinal cells have been successfully transplanted from one monkey to another without need of immunosuppressant drugs.

Aug

In Japan, women in science seek allies, resources in push for gender equality

by admin | What's Up With Us

neuroamanda talks about gender equality for female scientists is Japan.

Aug

Measuring altitude — with clocks?

by jens wilkinson | Drop of science

Measuring altitude using atomic clocks seems like a crazy idea, but it’s already being done at RIKEN in Japan

Aug

The sound of molecules: NMR-inspired music

by adam phillips | Research in Depth, Science Heavy

Science & art: how NMR works and how NMR spectra have been used to compose music based on molecular structures.

Photosynthetic bacteria spin spider silk for the masses

A little genetic engineering and a special recipe allows photosynthetic bacteria to mass-produce super lightweight spider silk for use in manufacturing.

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Why (mouse) mothers take risks to protect their infants

The calcitonin receptor and its ligand amylin act in the brain to motivate mouse mothers to protect their pups, even in risky/dangerous situations.

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Gut bacteria could help overcome milk allergy

Analysis shows that some gut bacteria could help improve oral immunotherapy against milk allergy.

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Gene linked to intellectual ability affects memory replay in mice

Scientists have discovered a gene in mice that allows memory replay at rest, a process necessary for forming long-lasting memories in mice.

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Imaging whole-body cancer metastasis at the single-cell level

A new optical clearing method allows imaging of cancer metastasis at incredibly high resolution.

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Pathogenic genetic variation linked to H. pylori-related stomach cancer

Researchers find that the risk of stomach cancer due to infection withH. Pylori bacteria increases with specific genetic variations.

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Aug

Mathematical model predicts self-organized learning in real neurons

by adam phillips | Hot Off the Press

The free energy principle predicted how real neural connections changed as neurons “learned” in a dish.

Aug

Deadly fungi beaten with fatty acid synthase inhibitor

by adam phillips | Hot Off the Press

A new approach to attacking fungi involves inhibiting a gene needed for making fatty acids.

Jul

A new and improved way to store hydrogen

by masataka sasabe | Hot Off the Press

A simple chemical reaction allows hydrogen-carrying ammonia to be stored and retrieved cheaply and easily.

Jun

A new alpha-particle treatment for multiple cancers

by adam phillips | Hot Off the Press

A new type of alpha-particle therapy allows selective targeting of tumors in multiple cancers.

Jun

A researcher’s journey: from surfing to studying pain

by adam phillips | Interviews

Joshua Johansen from RIKEN CBS tells us about his journey from surfer to pain researcher and beyond. Stay tuned for part II …

Jun

The first drug treatment for brain aneurysms (in mice)

by adam phillips | Hot Off the Press

Scientists discover that most aneurysms result from mutations. A mouse model shows they can be treated with drugs.

Jun

Simple but revolutionary modular organoids

by jens wilkinson | Hot Off the Press

A new way to construct complex 3D organoids without using elaborate techniques! The trick using modular cubes with hydrogel layers.

May

Thoughts on the genetics of medicinal licorice

by jens wilkinson | Drop of science

Jens talks about licorice and a recent RIKEN study that finally mapped its genome.

Apr

Pathogenic genetic variation linked to H. pylori-related stomach cancer

by adam phillips | Hot Off the Press

Researchers find that the risk of stomach cancer due to infection withH. Pylori bacteria increases with specific genetic variations.

New lab-grown retinal sheets almost ready for clinical trials

A new retinal transplant technique works by preventing bipolar cells from maturing in lab-grown retinal sheets.

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Next stop: clinical hair regeneration

A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.

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New treatment assembles cancer drug inside the body

Cancer drugs assembled inside the body on cancer cells should reduce harmful side effects to other tissue.

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Eating a high fat diet without getting obese?

Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.

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Apr

Gut bacteria could help overcome milk allergy

by adam phillips | Hot Off the Press

Analysis shows that some gut bacteria could help improve oral immunotherapy against milk allergy.

Apr

Detecting pathogens: the evolution of plant immunity

by masataka sasabe | Hot Off the Press

Scientists find recognition receptors for plant growth and plant immunity that share a common evolutionary origin.

Mar

Genomic “butterfly effect” involving TADs explains risk for autism

by masataka sasabe | Hot Off the Press

De novo mutations in three-dimensional structures in the genome containing known ASD genes were found to be associated with ASD risk.

Mar

Heat used to transform antiskyrmions to skyrmions and back

by jens wilkinson | Hot Off the Press

Scientists discover a way to transform antiskyrmions to skyrmions and back using heat and magnetic fields.

Jan

Real webshooters? Synthetic spider silk spun from artificial gland

by adam phillips | Hot Off the Press

Scientists create a microfluidic device that spins artificial spider silk from spidroins proteins, duplicating silk’s complex molecular structure.

Jan

Omics Omics Omics: Analysis predicts ovarian cancer-treating drug

by adam phillips | Hot Off the Press

Multi-omics analysis prediction: drugs that inhibit Ras signaling will help prevent tumor formation in serous ovarian cancer.

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