Smarter AI: machine learning without negative data

Scientists have developed a new method for machine learning that allows an AI to make better classifications without negative data.

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Eve Marder: freeing knowledge, crashing neurons

None of us would get on a plane that had its parts changed in mid-air, says Eve Marder, who has spent her career probing a very specific cluster of crustacean nerve cells. Yet we are all walking around undergoing a constant turnover of cellular parts, and so are the lobsters and crabs Marder studies.

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Xist knockout rescues miscarriages in mice

Xist knockout rescues miscarriages in mice whose egg cells lack H3K27me3 epigenetic instructions.
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Albumin drops medicine off at cancer site then leaves the body

By changing albumin’s identity, drugs can carried to their targets and then removed from the body after being used.
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Omics Omics Omics: Analysis predicts ovarian cancer-treating drug

Multi-omics analysis prediction: drugs that inhibit Ras signaling will help prevent tumor formation in serous ovarian cancer.
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Stem cell exhaustion and proliferation: An aging fly’s tale

Blocking the gene ced-6 led to stem cell exhaustion in aging fruit flies and prevented repair of damaged intestines.
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Dec

11

Science communication symposium

Science communication symposium

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Friday I participated in a small symposium that focused on science communication (for institutions in Japan). We discussed using social media as a means to self-publish wow! and amazing! research findings. Here are some of my thoughts about how useful this plays out in Japan.

Something smells fishy: categorizing odors in the brain

Calcium imaging and mathematical model explain how categories and mixtures of odors are represented in the fly brain and consistent across individual flies.
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Low-protein diet changes sperm and health of future offspring

Low-protein diets in male mice alter sperm and result in offspring that have metabolic problems like diabetes in adulthood.
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Skipping fatty acids could be recipe for schizophrenia

Prenatal lack of omega-3 and omega-6 fatty acids linked to epigenetic changes that lead to schizophrenic symptoms in mice.

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Genomic “butterfly effect” involving TADs explains risk for autism

De novo mutations in three-dimensional structures in the genome containing known ASD genes were found to be associated with ASD risk.
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A new type of cell death discovered in fly guts

A completely unknown type of cell death called “erebosis” has been discovered in the guts of the common fruit fly.
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The sound of molecules: NMR-inspired music

Science & art: how NMR works and how NMR spectra have been used to compose music based on molecular structures.

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Why (mouse) mothers take risks to protect their infants

The calcitonin receptor and its ligand amylin act in the brain to motivate mouse mothers to protect their pups, even in risky/dangerous situations.
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Super-thin wearable electronics just got more flexible

A method for making super-flexible and ultra-thin wearable electronics uses water-vapor plasma to create gold-gold bonds.
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Opossums are the first genome edited marsupials

A new piezoelectronic microinjection method has allowed the first successful genome editing in marsupials: albino opossums.
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New treatment assembles cancer drug inside the body

Cancer drugs assembled inside the body on cancer cells should reduce harmful side effects to other tissue.
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