CAPON links Alzheimer’s plaques to neurodegeneration


CAPON was found to link Aβ plaques and hippocampal neurodegeneration in mice, explaining how these two hallmarks of Alzheimer’s disease are related.

Diagnosing fetal heart disease benefits from explanatory AI


Diagnosis accuracy improved when doctors used explanatory AI to help diagnose congenital heart disease from fetal ultrasound videos.

Sphingolipid S1P: Potential new target for schizophrenia treatment


Sphingolipid S1P is reduced in brain white matter of people with schizophrenia, making S1P receptors a good target for new treatments.

A new type of cell death discovered in fly guts


A completely unknown type of cell death called “erebosis” has been discovered in the guts of the common fruit fly.

Quick, call Spiderman: scientists discover how spider silk is formed


A group of scientists led by researchers have discovered a key mechanism through which spider silk is formed.

Imaging whole-body cancer metastasis at the single-cell level


A new optical clearing method allows imaging of cancer metastasis at incredibly high resolution.

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Self-assembly of spider silk

This gut microbe might protect against diabetes and reduce insulin resistance

NEW: One-way hydrogel guides motion of tiny worms!

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Aug

17

Eve Marder: freeing knowledge, crashing neurons

Eve Marder: freeing knowledge, crashing neurons


None of us would get on a plane that had its parts changed in mid-air, says Eve Marder, who has spent her career probing a very specific cluster of crustacean nerve cells. Yet we are all walking around undergoing a constant turnover of cellular parts, and so are the lobsters and crabs Marder studies.

Aug

5

RIKEN Research Summer issue

RIKEN Research Summer issue


A quick post to let you know that the Summer issue of RIKEN Research Magazine came out towards the end of June. This issue covers brain evolution, regenerating skin, super-clear synapses, and much much more! Enjoy!

Jun

3

RIKEN Research Spring issue is here

RIKEN Research Spring issue is here


Just a quick post to let you know that the Spring issue of RIKEN Research Magazine came out towards the end of March. This issue covers issues including the discovery of element 113, earth-friendly pesticides, and the secrets of a rice-killing fungal toxin. Enjoy!

Dec

11

Science communication symposium

Science communication symposium


Friday I participated in a small symposium that focused on science communication (for institutions in Japan). We discussed using social media as a means to self-publish wow! and amazing! research findings. Here are some of my thoughts about how useful this plays out in Japan.

AI used to detect fetal heart problems


Researchers have developed a novel system that can automatically detect abnormalities in fetal hearts in real-time using artificial intelligence (AI). ???❤️

Heat shock system helps dried up bug come back to life


An international collaboration has determined that cooption of the Heat Shock Factor (HSF) gene system is what allows larvae of the sleeping chironomid to be able to survive severe desiccation.

Promising mouse model for Ngly1 deficiency


A recent study of Ngly1 deficient mice used a secondary knockout to create double knockouts with symptoms similar to human NGLY1 deficiency.

Leaky plants bad for drought resistance


The KAI2 receptor for compounds found in smoke helps plants retain water and survive during drought.

RIKEN discovers new T cells related to immune disorders


Immune-related diseases like multiple sclerosis associated with genetic variation in newly discovered, rare T cells.

Freedom from fear ?‍♀️


Researchers discover a dopaminergic circuit in the brain that allows fear associations to disappear when there isn’t anything to be afraid of anymore.

Opossums are the first genome edited marsupials


A new piezoelectronic microinjection method has allowed the first successful genome editing in marsupials: albino opossums.

How does gravity affect antimatter?


Scientists find that antimatter reacts to gravity the same way that regular matter does.

Social contact-seeking behavior and loneliness in the brain


Levels of the peptide amylin in the brain are related to loneliness; activating amylin neurons in the MPOA drives isolated mice to seek social contact.

Next stop: clinical hair regeneration


A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.