The It Ain't Magic Science Blog

Blocking obesity with a protein-sugar combination

Discovery of an enzyme that prevents obesity in mice through glycosylation of a protein involved fat-cell differentiation.

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In living color: imaging the brain with synthetic bioluminescence

A new way to image the brain from outside the head using bioluminescence.

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Smoker gut bacteria reduce bowel inflammation in ulcerative colitis

Mouth bacteria that settle in the guts of smokers activate helper T-cells that counter inflammation in ulcerative colitis.

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Hibernation-like state can protect kidneys during heart surgery

Activating Q-neurons in the mouse brain led to a hibernation-like state that protected kidneys during heart surgery.

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H2AK119ub1: How you inherit acquired traits from your mom

H2AK119ub1. Say that three times really fast! But seriously, it allows maternally acquired traits to be inherited.

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Gut bacteria could help overcome milk allergy

Analysis shows that some gut bacteria could help improve oral immunotherapy against milk allergy.

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Self-assembly of spider silk

This gut microbe might protect against diabetes and reduce insulin resistance

NEW: One-way hydrogel guides motion of tiny worms!

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Memories are made of this ?? – (Part 2)

Thomas McHugh from the RIKEN Center for Brain Science continues his discussion about memories, emotions, the brain, and life.

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Xist knockout rescues miscarriages in mice

Xist knockout rescues miscarriages in mice whose egg cells lack H3K27me3 epigenetic instructions.

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Brain wave synchrony can predict memory age

The degree of neuronal synchrony between the anterior cingulate cortex and the hippocampus during recall is an indication of memory age (in mice).

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Albumin drops medicine off at cancer site then leaves the body

By changing albumin’s identity, drugs can carried to their targets and then removed from the body after being used.

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Heat used to transform antiskyrmions to skyrmions and back

Scientists discover a way to transform antiskyrmions to skyrmions and back using heat and magnetic fields.

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Opto-OISI: imaging connections in the living brain

A new imaging technique called opto-OISI allows scientists to non-invasively visualize where specific neurons project in the living brain.

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Sep

AI used to detect fetal heart problems

by masataka sasabe | News

Researchers have developed a novel system that can automatically detect abnormalities in fetal hearts in real-time using artificial intelligence (AI). ???❤️

Sep

Protostars that exhibit large diversity in organic compounds

by riken research highlights | Research Highlight

A survey of a molecular cloud has found that the organic chemical makeup of protostars varies considerably.

Sep

Scientists solve epigenetic barriers to cloning

by jens wilkinson | Hot Off the Press

Scientists show that two epigenetic factors improve the success rate of cloning via somatic cell nuclear transfer.

Aug

Transgenic plants ??on acid survive without water

by adam phillips | Featured, Research Highlight

Scientists designed transgenic plants that survive drought-like conditions by bumping up acetic acid production only when water is scarce.

Aug

Two genes that regulate how much we dream

by masataka sasabe | Hot Off the Press

An international research team led by RIKEN BDR has identified a pair of genes that regulate how much REM (dream) and non-REM sleep an animal experiences.

Aug

Flies use fecal deposits as pheromones

by admin | Hot Off the Press

Bioluminescence imaging of fly brains reveals neurons sensitive to fly poo laced with pheromones (you can see the fecal “landmark” in the dotted circle). Need we say more?

Jul

Hippocampal memory isn’t all about place cells

by admin | Hot Off the Press

Scientists have found evidence that hippocampal memories of experience are not stored in place cells.

Jul

Summer fun: how plants beat the heat

by adam phillips | Hot Off the Press

Scientists have discovered a gene that allows plants to cope with extreme heat by changing the composition of chloroplast membranes.

Jun

Freedom from fear ?‍♀️

by adam phillips | Hot Off the Press

Researchers discover a dopaminergic circuit in the brain that allows fear associations to disappear when there isn’t anything to be afraid of anymore.

Next stop: clinical hair regeneration

A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.

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H2AK119ub1: How you inherit acquired traits from your mom

H2AK119ub1. Say that three times really fast! But seriously, it allows maternally acquired traits to be inherited.

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Opossums are the first genome edited marsupials

A new piezoelectronic microinjection method has allowed the first successful genome editing in marsupials: albino opossums.

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Green hydrogen production for fuel cells and fertilizers

A new method of water electrolysis avoids rare metals, making hydrogen production green and sustainable.

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Aug

Gut bacteria double team worsens symptoms of multiple sclerosis

by adam phillips | Hot Off the Press

Joint activity of two gut bacteria leads to excessive MOG-specific T-cell activity and demyelination of neurons in the spinal cord of a mouse model of multiple sclerosis.

Aug

Something smells fishy: categorizing odors in the brain

by masataka sasabe | Hot Off the Press

Calcium imaging and mathematical model explain how categories and mixtures of odors are represented in the fly brain and consistent across individual flies.

Jul

Photosynthetic bacteria spin spider silk for the masses

by masataka sasabe | Hot Off the Press

A little genetic engineering and a special recipe allows photosynthetic bacteria to mass-produce super lightweight spider silk for use in manufacturing.