The It Ain't Magic Science Blog

Diazoxide pills for Alzheimer’s disease?

Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.

From evolutionary morphology to Godzilla

I recently spoke with RIKEN scientist Shigeru Kuratani about evolutionary morphology, sci-fi monsters, the genius of Alien, and more.

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Astrocytes powered by norepinephrine during fear-memory formation

Norepinephrine released in the locus coeruleus during fear learning is accompanied by increased calcium and cAMP levels in nearby astrocytes.

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Physiological origami and proper body development in flies

Genetics and mechanical origami in the fly embryo helps proper body development by fighting off “noisy” fluctuations is the environment.

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AdR blockers protect the brain from stroke damage

Treatment with adrenergic receptor antagonists (AdR blockers) was able to reduce stroke-related brain damage in mice and improve motor recovery.

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How does gravity affect antimatter?

Scientists find that antimatter reacts to gravity the same way that regular matter does.

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Latest research animations

Self-assembly of spider silk

This gut microbe might protect against diabetes and reduce insulin resistance

NEW: One-way hydrogel guides motion of tiny worms!

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Cassava engineered to produce healthier tapioca starch

Reducing the amount of starch branching enzymes in cassava plants made more resistant and thus healthier tapioca starch.

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Astrocytes powered by norepinephrine during fear-memory formation

Norepinephrine released in the locus coeruleus during fear learning is accompanied by increased calcium and cAMP levels in nearby astrocytes.

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Cubes of brain tissue allow drug discovery without animals

Modeling the blood-brain-barrier with brains-in-a-cube allows drug testing without the need for animals.

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RIKEN Research Summer issue

A quick post to let you know that the Summer issue of RIKEN Research Magazine came out towards the end of June. This issue covers brain evolution, regenerating skin, super-clear synapses, and much much more! Enjoy!

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Toward human hibernation: cold-resistant mouse stem cells

Cold-resistant stem cells from “deep torpor” mice are a big step toward understanding why tissue survives hibernation.

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Mutation protects against Alzheimer’s disease in mice

Scientists discover a deletion mutation that reduces amyloid-beta plaque formation in Alzheimer’s disease model mice.

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Sep

Scientists solve epigenetic barriers to cloning

by jens wilkinson | Hot Off the Press

Scientists show that two epigenetic factors improve the success rate of cloning via somatic cell nuclear transfer.

Aug

Transgenic plants ??on acid survive without water

by adam phillips | Featured, Research Highlight

Scientists designed transgenic plants that survive drought-like conditions by bumping up acetic acid production only when water is scarce.

Aug

Two genes that regulate how much we dream

by masataka sasabe | Hot Off the Press

An international research team led by RIKEN BDR has identified a pair of genes that regulate how much REM (dream) and non-REM sleep an animal experiences.

Aug

Flies use fecal deposits as pheromones

by admin | Hot Off the Press

Bioluminescence imaging of fly brains reveals neurons sensitive to fly poo laced with pheromones (you can see the fecal “landmark” in the dotted circle). Need we say more?

Jul

Hippocampal memory isn’t all about place cells

by admin | Hot Off the Press

Scientists have found evidence that hippocampal memories of experience are not stored in place cells.

Jul

Summer fun: how plants beat the heat

by adam phillips | Hot Off the Press

Scientists have discovered a gene that allows plants to cope with extreme heat by changing the composition of chloroplast membranes.

Jun

Freedom from fear ?‍♀️

by adam phillips | Hot Off the Press

Researchers discover a dopaminergic circuit in the brain that allows fear associations to disappear when there isn’t anything to be afraid of anymore.

Jun

Blue gene regulation helps plants respond properly to light

by adam phillips | Hot Off the Press

Blue light alters some gene expression in plants by changing the transcription start sites to downstream locations.

Jun

Out on a limb: the many ‘brains’ of the octopus

by admin | Drop of science

Learn how (neurologically) cool octopus arms are (as if you didn’t already know).

Why (mouse) mothers take risks to protect their infants

The calcitonin receptor and its ligand amylin act in the brain to motivate mouse mothers to protect their pups, even in risky/dangerous situations.

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Opossums are the first genome edited marsupials

A new piezoelectronic microinjection method has allowed the first successful genome editing in marsupials: albino opossums.

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Super-thin wearable electronics just got more flexible

A method for making super-flexible and ultra-thin wearable electronics uses water-vapor plasma to create gold-gold bonds.

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Artificial gravity protects the immune system of mice in space

Mice who experienced artificial gravity on the ISS suffered less damage to their immune system (thymus) than weightless mice did.

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Jul

Photosynthetic bacteria spin spider silk for the masses

by masataka sasabe | Hot Off the Press

A little genetic engineering and a special recipe allows photosynthetic bacteria to mass-produce super lightweight spider silk for use in manufacturing.

Jun

Blood cell mutations linked to leukemia are inevitable

by adam phillips | Hot Off the Press

Researchers show that blood cell mutations increase with age identify risk factors for developing leukemia in Japanese and European populations.

Jun

Organic nitrogen in soil helps crop growth

by jens wilkinson | Hot Off the Press

Scientists used a multi-omics analysis to show that soil solarization helps crops grow because it increases organic nitrogen in the soil.

May

Consciousness, brain connections, and the claustrum

by admin | Hot Off the Press

Research shows that the claustrum acts as a ‘consciousness conductor’ that synchronizes and connects areas within the mouse brain.

May

A new imaging biomarker for the aging brain

by adam phillips | Hot Off the Press

Enlarged ventricles is a sign of an aging brain. New research shows that this phenomenon can be predicted by lagging brain circulation that is detected by MRI.