The It Ain't Magic Science Blog

Omics Omics Omics: Analysis predicts ovarian cancer-treating drug

Multi-omics analysis prediction: drugs that inhibit Ras signaling will help prevent tumor formation in serous ovarian cancer.

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Ultraprecise clocks and the Tokyo Skytree verify Einstein’s theory of relativity

Time measured at the top and bottom of the Tokyo Skytree with ultraprecise clocks has verified the time dilation effect predicted by Einstein.

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Eating a high fat diet without getting obese?

Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.

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Protein pileup affects social behavior through altered brain signaling

When a normal cellular cleanup process is disrupted, social behavior in mice is disrupted and they start behaving in ways that resemble human symptoms of autism spectrum disorder and schizophrenia.

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The free-energy principle explains neural network behavior

Scientists show that the free-energy principle can explain how neural networks work.

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Deep-brain exploration with nanomaterials

A new way to optogenetically activate neurons deep in the brain using infrared light and upconversion nanoparticles. It’s non-invasive!

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Latest research animations

Self-assembly of spider silk

This gut microbe might protect against diabetes and reduce insulin resistance

NEW: One-way hydrogel guides motion of tiny worms!

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Brainless memory makes the spinal cord smarter than previously thought

The spinal cord learns how to direct limb muscles to avoid aversive sensations and recalls the memories using separate neural circuitry. Oh, and without a brain!

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Organ regeneration in the lab

Interview with Takashi Tsuji, team leader of the Laboratory for Organ Regeneration at the RIKEN Center for Developmental Biology

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Learning and unlearning to fear: The two faces of noradrenaline

Fear association and unlearning fear association require different populations of noradrenaline neurons in the locus coeruleus.

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Award-winning 3D images of living cells

An interview with Yuko Kiyosue, discussing the 3D images of living cells that gained her and her colleagues a recent award.

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The first drug treatment for brain aneurysms (in mice)

Scientists discover that most aneurysms result from mutations. A mouse model shows they can be treated with drugs.

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From evolutionary morphology to Godzilla

I recently spoke with RIKEN scientist Shigeru Kuratani about evolutionary morphology, sci-fi monsters, the genius of Alien, and more.

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Sep

Scientists solve epigenetic barriers to cloning

by jens wilkinson | Hot Off the Press

Scientists show that two epigenetic factors improve the success rate of cloning via somatic cell nuclear transfer.

Aug

Transgenic plants ??on acid survive without water

by adam phillips | Featured, Research Highlight

Scientists designed transgenic plants that survive drought-like conditions by bumping up acetic acid production only when water is scarce.

Aug

Two genes that regulate how much we dream

by masataka sasabe | Hot Off the Press

An international research team led by RIKEN BDR has identified a pair of genes that regulate how much REM (dream) and non-REM sleep an animal experiences.

Aug

Flies use fecal deposits as pheromones

by admin | Hot Off the Press

Bioluminescence imaging of fly brains reveals neurons sensitive to fly poo laced with pheromones (you can see the fecal “landmark” in the dotted circle). Need we say more?

Jul

Hippocampal memory isn’t all about place cells

by admin | Hot Off the Press

Scientists have found evidence that hippocampal memories of experience are not stored in place cells.

Jul

Summer fun: how plants beat the heat

by adam phillips | Hot Off the Press

Scientists have discovered a gene that allows plants to cope with extreme heat by changing the composition of chloroplast membranes.

Jun

Freedom from fear ?‍♀️

by adam phillips | Hot Off the Press

Researchers discover a dopaminergic circuit in the brain that allows fear associations to disappear when there isn’t anything to be afraid of anymore.

Jun

Blue gene regulation helps plants respond properly to light

by adam phillips | Hot Off the Press

Blue light alters some gene expression in plants by changing the transcription start sites to downstream locations.

Jun

Out on a limb: the many ‘brains’ of the octopus

by admin | Drop of science

Learn how (neurologically) cool octopus arms are (as if you didn’t already know).

Next stop: clinical hair regeneration

A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.

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Eating a high fat diet without getting obese?

Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.

Read on

New treatment assembles cancer drug inside the body

Cancer drugs assembled inside the body on cancer cells should reduce harmful side effects to other tissue.

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Artificial gravity protects the immune system of mice in space

Mice who experienced artificial gravity on the ISS suffered less damage to their immune system (thymus) than weightless mice did.

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Jul

Photosynthetic bacteria spin spider silk for the masses

by masataka sasabe | Hot Off the Press

A little genetic engineering and a special recipe allows photosynthetic bacteria to mass-produce super lightweight spider silk for use in manufacturing.

Jun

Blood cell mutations linked to leukemia are inevitable

by adam phillips | Hot Off the Press

Researchers show that blood cell mutations increase with age identify risk factors for developing leukemia in Japanese and European populations.

Jun

Organic nitrogen in soil helps crop growth

by jens wilkinson | Hot Off the Press

Scientists used a multi-omics analysis to show that soil solarization helps crops grow because it increases organic nitrogen in the soil.

May

Consciousness, brain connections, and the claustrum

by admin | Hot Off the Press

Research shows that the claustrum acts as a ‘consciousness conductor’ that synchronizes and connects areas within the mouse brain.

May

A new imaging biomarker for the aging brain

by adam phillips | Hot Off the Press

Enlarged ventricles is a sign of an aging brain. New research shows that this phenomenon can be predicted by lagging brain circulation that is detected by MRI.