Centennial RIKEN Research


???This Spring we’ve put together a special centennial issue of RIKEN Research ???

Protein pileup affects social behavior through altered brain signaling


When a normal cellular cleanup process is disrupted, social behavior in mice is disrupted and they start behaving in ways that resemble human symptoms of autism spectrum disorder and schizophrenia.

Social contact-seeking behavior and loneliness in the brain


Levels of the peptide amylin in the brain are related to loneliness; activating amylin neurons in the MPOA drives isolated mice to seek social contact.

RIKEN Research Fall Issue


Fall is here, and with it comes the latest issue of RIKEN Research. This issue covers tactile learning during sleep, supercomputers and simulations, solar cells, fly olfaction, tumor vaccines, and more

Cassava engineered to produce healthier tapioca starch


Reducing the amount of starch branching enzymes in cassava plants made more resistant and thus healthier tapioca starch.

A new alpha-particle treatment for multiple cancers


A new type of alpha-particle therapy allows selective targeting of tumors in multiple cancers.

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Mutation protects against Alzheimer’s disease in mice


Scientists discover a deletion mutation that reduces amyloid-beta plaque formation in Alzheimer’s disease model mice.

Transgenic plants ??on acid survive without water


Scientists designed transgenic plants that survive drought-like conditions by bumping up acetic acid production only when water is scarce.

Mutation links bipolar disorder to mitochondrial disease


ANT1 mutations found in bipolar disease that affect mitochondria lead to hyperexcitable serotonergic neuronal activity in the brain.

Ultraprecise clocks and the Tokyo Skytree verify Einstein’s theory of relativity


Time measured at the top and bottom of the Tokyo Skytree with ultraprecise clocks has verified the time dilation effect predicted by Einstein.

Diagnosing fetal heart disease benefits from explanatory AI


Diagnosis accuracy improved when doctors used explanatory AI to help diagnose congenital heart disease from fetal ultrasound videos.

Chromosome copying errors pinpointed in developing embryos


The DNA duplication process changes during embryogenesis and chromosome copying errors increase during the transition.
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The stars align

The stars align


The stars align. That’s what you say, when things work out perfectly. In the case of an eclipse, of course, it’s not stars that align but rather the moon and sun.

Why (mouse) mothers take risks to protect their infants


The calcitonin receptor and its ligand amylin act in the brain to motivate mouse mothers to protect their pups, even in risky/dangerous situations.

Opossums are the first genome edited marsupials


A new piezoelectronic microinjection method has allowed the first successful genome editing in marsupials: albino opossums.

Diazoxide pills for Alzheimer’s disease?


Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.

New treatment assembles cancer drug inside the body


Cancer drugs assembled inside the body on cancer cells should reduce harmful side effects to other tissue.