Mutation links bipolar disorder to mitochondrial disease

ANT1 mutations found in bipolar disease that affect mitochondria lead to hyperexcitable serotonergic neuronal activity in the brain.

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A researcher’s journey part 2: emotional memory and being human

Joshua Johansen from RIKEN CBS explains emotional memory, what his lab is doing, and what makes a good researcher.
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Cyborg cockroaches to the rescue!

The key to this remote-controllable cyborg cockroach is a solar-cell rechargeable battery and an ultrathin flexible backpack.
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AI identifies features associated with cancer recurrence

Artificial intelligence has successfully identified features relevant to cancer prognosis that were not previously noted by pathologists
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Superfly flight simulator helps unravel navigation in the brain

Optical imaging neural activity in flies as they use a flight simulator can help us understand how the brain codes navigation.

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Eve Marder: freeing knowledge, crashing neurons

None of us would get on a plane that had its parts changed in mid-air, says Eve Marder, who has spent her career probing a very specific cluster of crustacean nerve cells. Yet we are all walking around undergoing a constant turnover of cellular parts, and so are the lobsters and crabs Marder studies.

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Melatonin in mice, circadian rhythms, and daily torpor

A new breed of lab mouse allows the study of naturally occurring melatonin. These mice will adjust better to jetlag than regular lab mice and experience daily torpor.
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Detecting pathogens: the evolution of plant immunity

Scientists find recognition receptors for plant growth and plant immunity that share a common evolutionary origin.
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Introducing Nikola, the emotional android boy

A new android named Nikola will help researchers study facial expressions, emotions, and social interactions.
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Centennial RIKEN Research

???This Spring we’ve put together a special centennial issue of RIKEN Research ???

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First hydride-ion battery that works at room temperature

Researchers develop a new solid electrolyte that can conduct hydride ions, thus allowing better hydrogen-based batteries and fuel cells.
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Trigger region found for epileptic absence seizures

A mouse model shows that absence seizures are triggered by faulty connections between the cortex and fast-spiking neurons in the striatum.

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Diazoxide pills for Alzheimer’s disease?

Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.
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New lab-grown retinal sheets almost ready for clinical trials

A new retinal transplant technique works by preventing bipolar cells from maturing in lab-grown retinal sheets.
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Next stop: clinical hair regeneration

A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.
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New treatment assembles cancer drug inside the body

Cancer drugs assembled inside the body on cancer cells should reduce harmful side effects to other tissue.
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