The It Ain't Magic Science Blog

Promising mouse model for Ngly1 deficiency

A recent study of Ngly1 deficient mice used a secondary knockout to create double knockouts with symptoms similar to human NGLY1 deficiency.

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Strong emotions plus non-REM sleep equals longer-lasting perceptual memories

Perceptual memories linked to positive emotions, such as joy or happiness, are strengthened during sleep, specifically during periods of deep non-REM sleep.

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The joys of computational mass spectrometry

Scientists have developed a new automated computational mass spectrometry system that can search an organism’s entire metabolome for as-yet-unknown metabolites (potential drugs).

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Skipping fatty acids could be recipe for schizophrenia

Prenatal lack of omega-3 and omega-6 fatty acids linked to epigenetic changes that lead to schizophrenic symptoms in mice.

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Artificial gravity protects the immune system of mice in space

Mice who experienced artificial gravity on the ISS suffered less damage to their immune system (thymus) than weightless mice did.

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Mathematical model predicts self-organized learning in real neurons

The free energy principle predicted how real neural connections changed as neurons “learned” in a dish.

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Latest research animations

Self-assembly of spider silk

This gut microbe might protect against diabetes and reduce insulin resistance

NEW: One-way hydrogel guides motion of tiny worms!

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Imaging whole-body cancer metastasis at the single-cell level

A new optical clearing method allows imaging of cancer metastasis at incredibly high resolution.

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Recipe for hydrogen: sprinkle manganese oxide with iridium atoms, add water

A few iridium atoms also go a long way. When sprinkled on manganese oxide, hydrogen is produced with 95% less iridium!

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Mutation links bipolar disorder to mitochondrial disease

ANT1 mutations found in bipolar disease that affect mitochondria lead to hyperexcitable serotonergic neuronal activity in the brain.

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Gut bacteria could help overcome milk allergy

Analysis shows that some gut bacteria could help improve oral immunotherapy against milk allergy.

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How does gravity affect antimatter?

Scientists find that antimatter reacts to gravity the same way that regular matter does.

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From evolutionary morphology to Godzilla

I recently spoke with RIKEN scientist Shigeru Kuratani about evolutionary morphology, sci-fi monsters, the genius of Alien, and more.

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Dec

AI identifies features associated with cancer recurrence

by masataka sasabe | Hot Off the Press

Artificial intelligence has successfully identified features relevant to cancer prognosis that were not previously noted by pathologists

Nov

Longevity in supercentenarians linked to cytotoxic T-cells

by jens wilkinson | Hot Off the Press

Blood analysis in supercentenarians showed that they have many more cytotoxic CD4 T-cells than people with average life spans.

Oct

Schizophrenia biomarker (hydrogen sulfide) in human hair

by adam phillips | Hot Off the Press

Not only is hydrogen sulfide a good biomarker for schizophrenia, it’s also the culprit and a new starting point for drug discovery.

Oct

Brain tissue kept alive for weeks with new microfluidic device

by adam phillips | Hot Off the Press

A new microfluidic device can keep tissue cultures functional for weeks on an artificial membrane

Oct

Massive filaments, galaxies, and supermassive black holes

by jens wilkinson | Hot Off the Press

Big telescopes yield big data! Detailed observations gas filaments connecting galaxies in a distant proto-cluster in the early Universe.

Oct

Understanding non-coding DNA: gene “enhancers”

by jens wilkinson | Hot Off the Press

NETCAGE is a newly developed technique for determining the structure of portions of the non-coding genome called ‘enhancers.’

Aug

Mini-EUSO launched to the International Space Station ?

by jens wilkinson | News

The Mini-EUSO observatory was successfully launched to the International Space Station aboard the Soyuz MS14! NASA video inside!

Aug

Implantable blastocyst‐like cysts grown from stem cells

by adam phillips | Hot Off the Press

Embryo Organoids?! Blastocyst‐like cysts grown from pluripotent mouse stem cells were similar to natural blastocysts (early embryos).

Jul

Talking science Illustration with Misaki Ouchida

by adam phillips | Featured, Interviews, What's Up With Us

Whether it’s bird anatomy or science cartoons, Masaki Ouchida can do it all. She spoke with us about her career in science illustration, from the US to Japan.

How does gravity affect antimatter?

Scientists find that antimatter reacts to gravity the same way that regular matter does.

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Super-thin wearable electronics just got more flexible

A method for making super-flexible and ultra-thin wearable electronics uses water-vapor plasma to create gold-gold bonds.

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H2AK119ub1: How you inherit acquired traits from your mom

H2AK119ub1. Say that three times really fast! But seriously, it allows maternally acquired traits to be inherited.

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Diazoxide pills for Alzheimer’s disease?

Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.

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Dec

Cassava engineered to produce healthier tapioca starch

by adam phillips | Hot Off the Press

Reducing the amount of starch branching enzymes in cassava plants made more resistant and thus healthier tapioca starch.

Dec

Diazoxide pills for Alzheimer’s disease?

by adam phillips | Featured, Hot Off the Press

Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.

Oct

Zebrafish imagine a danger-free future to avoid threats in virtual reality

by admin | Hot Off the Press

By imaging the brain while zebrafish “swim” in virtual reality, scientists have learned that even fish can create internal models to predict future outcomes.