The It Ain't Magic Science Blog

Atlas of the aging lipidome highlights kidneys and gut bacteria

The atlas revealed sex differences in the aging kidney lipidome and lipid byproducts of gut bacteria that accumulate throughout the body.

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New lab-grown retinal sheets almost ready for clinical trials

A new retinal transplant technique works by preventing bipolar cells from maturing in lab-grown retinal sheets.

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Plant hormone combats dehydration

Scientists show that CLE25 is a plant hormone that travels from roots to leaves and helps close stomata in times of dehydration stress.

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Cyborg microchip valve driven by earthworm muscle

This earthworm muscle-controlled biological microelectromechanical system (bio‐MEMS) could lead the way to next-generation medical implants.

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Understanding non-coding DNA: gene “enhancers”

NETCAGE is a newly developed technique for determining the structure of portions of the non-coding genome called ‘enhancers.’

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Award-winning 3D images of living cells

An interview with Yuko Kiyosue, discussing the 3D images of living cells that gained her and her colleagues a recent award.

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Latest research animations

Self-assembly of spider silk

This gut microbe might protect against diabetes and reduce insulin resistance

NEW: One-way hydrogel guides motion of tiny worms!

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Cancer cells killed with artificial glycosylated metalloenzyme

Scientists have developed two cancer therapies that use an artificial glycosylated metalloenzyme to specifically target cancer cells in mice.

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RIKEN Research Spring issue is here

Just a quick post to let you know that the Spring issue of RIKEN Research Magazine came out towards the end of March. This issue covers issues including the discovery of element 113, earth-friendly pesticides, and the secrets of a rice-killing fungal toxin. Enjoy!

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Robotic AI helps efficient growth of replacement organs

Humans team-up with a robotic AI to speed up experiments to find the best way to regrow damaged eye tissue from stem cells.

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Robotic exoskeleton learns to help people stand up

This new robotic exoskeleton uses machine learning to know when users want help standing up.

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Detecting pathogens: the evolution of plant immunity

Scientists find recognition receptors for plant growth and plant immunity that share a common evolutionary origin.

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Bacterial drug resistance studied by robotic E. coli evolution

Experimentally evolving E. coli under pressure from a large number of antibiotics was able to identify constraints underlying evolved drug resistance.

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Dec

AI identifies features associated with cancer recurrence

by masataka sasabe | Hot Off the Press

Artificial intelligence has successfully identified features relevant to cancer prognosis that were not previously noted by pathologists

Nov

Longevity in supercentenarians linked to cytotoxic T-cells

by jens wilkinson | Hot Off the Press

Blood analysis in supercentenarians showed that they have many more cytotoxic CD4 T-cells than people with average life spans.

Oct

Schizophrenia biomarker (hydrogen sulfide) in human hair

by adam phillips | Hot Off the Press

Not only is hydrogen sulfide a good biomarker for schizophrenia, it’s also the culprit and a new starting point for drug discovery.

Oct

Brain tissue kept alive for weeks with new microfluidic device

by adam phillips | Hot Off the Press

A new microfluidic device can keep tissue cultures functional for weeks on an artificial membrane

Oct

Massive filaments, galaxies, and supermassive black holes

by jens wilkinson | Hot Off the Press

Big telescopes yield big data! Detailed observations gas filaments connecting galaxies in a distant proto-cluster in the early Universe.

Oct

Understanding non-coding DNA: gene “enhancers”

by jens wilkinson | Hot Off the Press

NETCAGE is a newly developed technique for determining the structure of portions of the non-coding genome called ‘enhancers.’

Aug

Mini-EUSO launched to the International Space Station ?

by jens wilkinson | News

The Mini-EUSO observatory was successfully launched to the International Space Station aboard the Soyuz MS14! NASA video inside!

Aug

Implantable blastocyst‐like cysts grown from stem cells

by adam phillips | Hot Off the Press

Embryo Organoids?! Blastocyst‐like cysts grown from pluripotent mouse stem cells were similar to natural blastocysts (early embryos).

Jul

Talking science Illustration with Misaki Ouchida

by adam phillips | Featured, Interviews, What's Up With Us

Whether it’s bird anatomy or science cartoons, Masaki Ouchida can do it all. She spoke with us about her career in science illustration, from the US to Japan.

Transgenic plants ??on acid survive without water

Scientists designed transgenic plants that survive drought-like conditions by bumping up acetic acid production only when water is scarce.

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Diazoxide pills for Alzheimer’s disease?

Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.

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Why (mouse) mothers take risks to protect their infants

The calcitonin receptor and its ligand amylin act in the brain to motivate mouse mothers to protect their pups, even in risky/dangerous situations.

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Green hydrogen production for fuel cells and fertilizers

A new method of water electrolysis avoids rare metals, making hydrogen production green and sustainable.

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Dec

Cassava engineered to produce healthier tapioca starch

by adam phillips | Hot Off the Press

Reducing the amount of starch branching enzymes in cassava plants made more resistant and thus healthier tapioca starch.

Dec

Diazoxide pills for Alzheimer’s disease?

by adam phillips | Featured, Hot Off the Press

Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.

Oct

Zebrafish imagine a danger-free future to avoid threats in virtual reality

by admin | Hot Off the Press

By imaging the brain while zebrafish “swim” in virtual reality, scientists have learned that even fish can create internal models to predict future outcomes.