Mutation links bipolar disorder to mitochondrial disease


ANT1 mutations found in bipolar disease that affect mitochondria lead to hyperexcitable serotonergic neuronal activity in the brain.

How an herbal medicine protects against inflamed bowels


A Japanese herbal medicine promotes good bacteria and innate immune cells in the gut, which protects against intestinal inflammation.

A new imaging biomarker for the aging brain


Enlarged ventricles is a sign of an aging brain. New research shows that this phenomenon can be predicted by lagging brain circulation that is detected by MRI.

Physiological origami and proper body development in flies


Genetics and mechanical origami in the fly embryo helps proper body development by fighting off “noisy” fluctuations is the environment.

New artificial skin helps avoid animal testing


A new artificial skin that reproduces proper tension can be used to research skin function and disease while reducing the need to experiment on animals.

Palaeospondylus: mystery of vertebrate evolution solved


Micro-CT scans using synchrotron radiation X-rays reveal Palaeospondylus morphology, finally allowing its placement on the evolutionary tree.

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Diagnosing fetal heart disease benefits from explanatory AI


Diagnosis accuracy improved when doctors used explanatory AI to help diagnose congenital heart disease from fetal ultrasound videos.

Dopamine reduces beta-amyloid plaques in Alzheimer’s disease


Increasing dopamine in the brains of AD model mice led to increased neprilysin, which broke down amyloid-beta plaques and improved memory.

The first drug treatment for brain aneurysms (in mice)


Scientists discover that most aneurysms result from mutations. A mouse model shows they can be treated with drugs.

Hepatoma (liver cancer) blocked by a sugar look-a-like


A sugar (fucose) analog can prevent liver cancer (hepatoma) from invading healthy liver cells.

Super-thin wearable electronics just got more flexible


A method for making super-flexible and ultra-thin wearable electronics uses water-vapor plasma to create gold-gold bonds.

Albumin drops medicine off at cancer site then leaves the body


By changing albumin’s identity, drugs can carried to their targets and then removed from the body after being used.
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The stars align

The stars align


The stars align. That’s what you say, when things work out perfectly. In the case of an eclipse, of course, it’s not stars that align but rather the moon and sun.

Transgenic plants ??on acid survive without water


Scientists designed transgenic plants that survive drought-like conditions by bumping up acetic acid production only when water is scarce.

Talking science Illustration with Misaki Ouchida


Whether it’s bird anatomy or science cartoons, Masaki Ouchida can do it all. She spoke with us about her career in science illustration, from the US to Japan.

How does gravity affect antimatter?


Scientists find that antimatter reacts to gravity the same way that regular matter does.

Next stop: clinical hair regeneration


A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.