The It Ain't Magic Science Blog

Root growth improved in soil contaminated with cesium

Overactivating the ABA signaling pathway in plants prevented cesium in soil from blocking root growth in plants.

Electrolithoautotrophs

Learn what electrolithoautotrophs are and how the scientists proved that A. ferrooxidans can use electric potential to fuel growth.

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Hepatoma (liver cancer) blocked by a sugar look-a-like

A sugar (fucose) analog can prevent liver cancer (hepatoma) from invading healthy liver cells.

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Toward human hibernation: cold-resistant mouse stem cells

Cold-resistant stem cells from “deep torpor” mice are a big step toward understanding why tissue survives hibernation.

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Something smells fishy: categorizing odors in the brain

Calcium imaging and mathematical model explain how categories and mixtures of odors are represented in the fly brain and consistent across individual flies.

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Low-protein diet changes sperm and health of future offspring

Low-protein diets in male mice alter sperm and result in offspring that have metabolic problems like diabetes in adulthood.

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Topics

Latest research animations

Self-assembly of spider silk

This gut microbe might protect against diabetes and reduce insulin resistance

NEW: One-way hydrogel guides motion of tiny worms!

Latest Posts

Oct

Protein antigens in meat, milk, and other foods suppress gut tumors

by adam phillips | Hot Off the Press

Food antigens were found to prevent small intestinal tumors in gut-tumor prone mice by making ensuring we have enough T cells for defense.

Oct

Stem cell exhaustion and proliferation: An aging fly’s tale

by masataka sasabe | Hot Off the Press

Blocking the gene ced-6 led to stem cell exhaustion in aging fruit flies and prevented repair of damaged intestines.

Aug

Chromosome copying errors pinpointed in developing embryos

by adam phillips | Hot Off the Press

The DNA duplication process changes during embryogenesis and chromosome copying errors increase during the transition.

Aug

Predictive grid cells help self navigation in the brain

by adam phillips | Hot Off the Press

Scientists have discovered grid cells in the brain that map an animal’s (or human’s) future position in space.

Aug

Dopamine reduces beta-amyloid plaques in Alzheimer’s disease

by adam phillips | Hot Off the Press

Increasing dopamine in the brains of AD model mice led to increased neprilysin, which broke down amyloid-beta plaques and improved memory.

Jul

RIKEN discovers new T cells related to immune disorders

by adam phillips | Hot Off the Press

Immune-related diseases like multiple sclerosis associated with genetic variation in newly discovered, rare T cells.

Jul

Will the “love hormone” ever be used to treat a rare genetic disease?

by masataka sasabe | Drop of science, What's Up With Us

One of the pitfalls of researching an extremely rare disease: getting enough data to support clinical trials could be impossible.

Jun

Purple biomass makes a good crop fertilizer

by adam phillips | Hot Off the Press

Biomass made from purple marine bacteria provides more than enough nitrogen to plants without harming the environment

Jun

Atlas of the aging lipidome highlights kidneys and gut bacteria

by masataka sasabe | Hot Off the Press

The atlas revealed sex differences in the aging kidney lipidome and lipid byproducts of gut bacteria that accumulate throughout the body.

May

Root growth improved in soil contaminated with cesium

by masataka sasabe | Hot Off the Press

Overactivating the ABA signaling pathway in plants prevented cesium in soil from blocking root growth in plants.

May

Japanese people are a mixture of three separate ancestral groups

by jens wilkinson | Hot Off the Press

A new study shows that the current Japanese population is derived from 3 ancestral groups, one of which brought Denisovan DNA to the party.

May

Space Café Tokyo explains sus sci-fi media

by kelly | What's Up With Us

Our very own Kelly writes about how much fun she had at Space Café Tokyo. Softcore science and beer.

May

Recipe for hydrogen: sprinkle manganese oxide with iridium atoms, add water

by adam phillips | Hot Off the Press

A few iridium atoms also go a long way. When sprinkled on manganese oxide, hydrogen is produced with 95% less iridium!

May

Stable green hydrogen production in a PEM electrolyzer

by adam phillips | Hot Off the Press

A little structurally manipulated manganese goes a long way when using a PEM electrolyzer to make hydrogen from water.

Apr

Brainless memory makes the spinal cord smarter than previously thought

by adam phillips | Hot Off the Press

The spinal cord learns how to direct limb muscles to avoid aversive sensations and recalls the memories using separate neural circuitry. Oh, and without a brain!

Apr

Eco-friendly ammonia production for fertilizers and alternative fuel

by adam phillips | Hot Off the Press

A new process that allows ammonia to be produced using much less energy than the standard methods.

Apr

Cubes of brain tissue allow drug discovery without animals

by masataka sasabe | Hot Off the Press

Modeling the blood-brain-barrier with brains-in-a-cube allows drug testing without the need for animals.

Apr

Gut bacteria could help overcome milk allergy

by adam phillips | Hot Off the Press

Analysis shows that some gut bacteria could help improve oral immunotherapy against milk allergy.

Apr

Detecting pathogens: the evolution of plant immunity

by masataka sasabe | Hot Off the Press

Scientists find recognition receptors for plant growth and plant immunity that share a common evolutionary origin.

Mar

Genomic “butterfly effect” involving TADs explains risk for autism

by masataka sasabe | Hot Off the Press

De novo mutations in three-dimensional structures in the genome containing known ASD genes were found to be associated with ASD risk.

Mar

Heat used to transform antiskyrmions to skyrmions and back

by jens wilkinson | Hot Off the Press

Scientists discover a way to transform antiskyrmions to skyrmions and back using heat and magnetic fields.

Jan

Real webshooters? Synthetic spider silk spun from artificial gland

by adam phillips | Hot Off the Press

Scientists create a microfluidic device that spins artificial spider silk from spidroins proteins, duplicating silk’s complex molecular structure.

Jan

Omics Omics Omics: Analysis predicts ovarian cancer-treating drug

by adam phillips | Hot Off the Press

Multi-omics analysis prediction: drugs that inhibit Ras signaling will help prevent tumor formation in serous ovarian cancer.

Dec

First hydride-ion battery that works at room temperature

by adam phillips | Hot Off the Press

Researchers develop a new solid electrolyte that can conduct hydride ions, thus allowing better hydrogen-based batteries and fuel cells.

Nov

Plants to the rescue: cleaning up our dirty soil

by adam phillips | Drop of science

A brief review of phytoremediation and research into how plants can be used to clean the environment.

Nov

Stolen genes used for parasitic mind control

by masataka sasabe | Hot Off the Press

Parasitic horsehair worms evolved to control their praying mantis hosts by stealing their genes (horizontal gene transfer).

Sep

Machine learning contributes to better quantum error correction

by jens wilkinson | Hot Off the Press

Researchers have developed an autonomous method for handling error correction in quantum computing. This will help quantum computers maintain their advantages over standard computers.

Sep

Laser melting ice-core sampler for studying climate change

by adam phillips | Hot Off the Press

This laser melting ice core sampler can determine temperature changes thousands of years ago on very fine timescale.

Aug

Gut bacteria reduces insulin resistance, protects against diabetes

by adam phillips | Hot Off the Press

Scientists discover gut bacteria that reduce insulin resistance in your body and sugar in your poo.

Aug

Scary places burned into our minds by constant memory replay

by riken research highlights | Research Highlight

Researchers discover the mechanism through which places associated with negative experiences are burned into our memories.

Aug

Toward human hibernation: cold-resistant mouse stem cells

by adam phillips | Hot Off the Press

Cold-resistant stem cells from “deep torpor” mice are a big step toward understanding why tissue survives hibernation.

Aug

A researcher’s journey part 2: emotional memory and being human

by adam phillips | Interviews

Joshua Johansen from RIKEN CBS explains emotional memory, what his lab is doing, and what makes a good researcher.

Aug

Mathematical model predicts self-organized learning in real neurons

by adam phillips | Hot Off the Press

The free energy principle predicted how real neural connections changed as neurons “learned” in a dish.

Aug

Deadly fungi beaten with fatty acid synthase inhibitor

by adam phillips | Hot Off the Press

A new approach to attacking fungi involves inhibiting a gene needed for making fatty acids.

Jul

A new and improved way to store hydrogen

by masataka sasabe | Hot Off the Press

A simple chemical reaction allows hydrogen-carrying ammonia to be stored and retrieved cheaply and easily.

Jun

A new alpha-particle treatment for multiple cancers

by adam phillips | Hot Off the Press

A new type of alpha-particle therapy allows selective targeting of tumors in multiple cancers.

Jun

A researcher’s journey: from surfing to studying pain

by adam phillips | Interviews

Joshua Johansen from RIKEN CBS tells us about his journey from surfer to pain researcher and beyond. Stay tuned for part II …

Jun

The first drug treatment for brain aneurysms (in mice)

by adam phillips | Hot Off the Press

Scientists discover that most aneurysms result from mutations. A mouse model shows they can be treated with drugs.

Jun

Simple but revolutionary modular organoids

by jens wilkinson | Hot Off the Press

A new way to construct complex 3D organoids without using elaborate techniques! The trick using modular cubes with hydrogel layers.

Gene linked to intellectual ability affects memory replay in mice

Scientists have discovered a gene in mice that allows memory replay at rest, a process necessary for forming long-lasting memories in mice.

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Decision-making during the COVID-19 pandemic

COVID-19 series — installment #2: RIKEN CBS Unit Leader Rei Akaishi talks about government decision-making during the pandemic.

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Next stop: clinical hair regeneration

A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.

Read on

The first drug treatment for brain aneurysms (in mice)

Scientists discover that most aneurysms result from mutations. A mouse model shows they can be treated with drugs.

Read on

First hydride-ion battery that works at room temperature

Researchers develop a new solid electrolyte that can conduct hydride ions, thus allowing better hydrogen-based batteries and fuel cells.

Read on

Gut bacteria double team worsens symptoms of multiple sclerosis

Joint activity of two gut bacteria leads to excessive MOG-specific T-cell activity and demyelination of neurons in the spinal cord of a mouse model of multiple sclerosis.

Read on

Oct

Protein antigens in meat, milk, and other foods suppress gut tumors

by adam phillips | Hot Off the Press

Food antigens were found to prevent small intestinal tumors in gut-tumor prone mice by making ensuring we have enough T cells for defense.

Oct

Stem cell exhaustion and proliferation: An aging fly’s tale

by masataka sasabe | Hot Off the Press

Blocking the gene ced-6 led to stem cell exhaustion in aging fruit flies and prevented repair of damaged intestines.

Aug

Chromosome copying errors pinpointed in developing embryos

by adam phillips | Hot Off the Press

The DNA duplication process changes during embryogenesis and chromosome copying errors increase during the transition.

Aug

Predictive grid cells help self navigation in the brain

by adam phillips | Hot Off the Press

Scientists have discovered grid cells in the brain that map an animal’s (or human’s) future position in space.

Aug

Dopamine reduces beta-amyloid plaques in Alzheimer’s disease

by adam phillips | Hot Off the Press

Increasing dopamine in the brains of AD model mice led to increased neprilysin, which broke down amyloid-beta plaques and improved memory.

Jul

RIKEN discovers new T cells related to immune disorders

by adam phillips | Hot Off the Press

Immune-related diseases like multiple sclerosis associated with genetic variation in newly discovered, rare T cells.

Jul

Will the “love hormone” ever be used to treat a rare genetic disease?

by masataka sasabe | Drop of science, What's Up With Us

One of the pitfalls of researching an extremely rare disease: getting enough data to support clinical trials could be impossible.

Jun

Purple biomass makes a good crop fertilizer

by adam phillips | Hot Off the Press

Biomass made from purple marine bacteria provides more than enough nitrogen to plants without harming the environment

Jun

Atlas of the aging lipidome highlights kidneys and gut bacteria

by masataka sasabe | Hot Off the Press

The atlas revealed sex differences in the aging kidney lipidome and lipid byproducts of gut bacteria that accumulate throughout the body.

Talking science Illustration with Misaki Ouchida

Whether it’s bird anatomy or science cartoons, Masaki Ouchida can do it all. She spoke with us about her career in science illustration, from the US to Japan.

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Next stop: clinical hair regeneration

A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.

Read on

H2AK119ub1: How you inherit acquired traits from your mom

H2AK119ub1. Say that three times really fast! But seriously, it allows maternally acquired traits to be inherited.

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Social contact-seeking behavior and loneliness in the brain

Levels of the peptide amylin in the brain are related to loneliness; activating amylin neurons in the MPOA drives isolated mice to seek social contact.