RIKEN Research Summer issue


A quick post to let you know that the Summer issue of RIKEN Research Magazine came out towards the end of June. This issue covers brain evolution, regenerating skin, super-clear synapses, and much much more! Enjoy!

Dopamine reduces beta-amyloid plaques in Alzheimer’s disease


Increasing dopamine in the brains of AD model mice led to increased neprilysin, which broke down amyloid-beta plaques and improved memory.

Promising mouse model for Ngly1 deficiency


A recent study of Ngly1 deficient mice used a secondary knockout to create double knockouts with symptoms similar to human NGLY1 deficiency.

Hibernation-like state can protect kidneys during heart surgery


Activating Q-neurons in the mouse brain led to a hibernation-like state that protected kidneys during heart surgery.

ERRg predicts atrial fibrillation and hidden comorbidity

Polygenic risk scores based on the genetic data from more that a million people predicted atrial fibrillation, stroke, and mortality.

What’s that smell? The advantage of sniffing


Rhythmic sniffing boosts phase-coded neuronal signals in the mouse olfactory bulb that allow odors to be identified.

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Albumin drops medicine off at cancer site then leaves the body


By changing albumin’s identity, drugs can carried to their targets and then removed from the body after being used.

Cancer cells killed with artificial glycosylated metalloenzyme


Scientists have developed two cancer therapies that use an artificial glycosylated metalloenzyme to specifically target cancer cells in mice.

Protein antigens in meat, milk, and other foods suppress gut tumors


Food antigens were found to prevent small intestinal tumors in gut-tumor prone mice by making ensuring we have enough T cells for defense.

Blue gene regulation helps plants respond properly to light


Blue light alters some gene expression in plants by changing the transcription start sites to downstream locations.

Super-thin wearable electronics just got more flexible


A method for making super-flexible and ultra-thin wearable electronics uses water-vapor plasma to create gold-gold bonds.

Ethanol pretreated soil protects plants from drought


Pretreating soil with ethanol protected plants, including wheat and rice, from the adverse effects of water deprivation.

Super-thin wearable electronics just got more flexible


A method for making super-flexible and ultra-thin wearable electronics uses water-vapor plasma to create gold-gold bonds.

Next stop: clinical hair regeneration


A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.

H2AK119ub1: How you inherit acquired traits from your mom


H2AK119ub1. Say that three times really fast! But seriously, it allows maternally acquired traits to be inherited.

Artificial gravity protects the immune system of mice in space


Mice who experienced artificial gravity on the ISS suffered less damage to their immune system (thymus) than weightless mice did.