The It Ain't Magic Science Blog

Dietary amino acid linked to cancer in flies

Researchers have found a dietary amino acid linked to oncogene expression / tumor formation; reduced consumption reduced cancer in flies.

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Astrocytes powered by norepinephrine during fear-memory formation

Norepinephrine released in the locus coeruleus during fear learning is accompanied by increased calcium and cAMP levels in nearby astrocytes.

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Eco-friendly ammonia production for fertilizers and alternative fuel

A new process that allows ammonia to be produced using much less energy than the standard methods.

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Confronting a string of epidemics including COVID-19

COVID-19 series — installment #1: RIKEN Executive Director Shigeo Koyasu talks about epidemics and what a good response looks like.

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Protein pileup affects social behavior through altered brain signaling

When a normal cellular cleanup process is disrupted, social behavior in mice is disrupted and they start behaving in ways that resemble human symptoms of autism spectrum disorder and schizophrenia.

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Artificial gravity protects the immune system of mice in space

Mice who experienced artificial gravity on the ISS suffered less damage to their immune system (thymus) than weightless mice did.

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Topics

Latest research animations

Self-assembly of spider silk

This gut microbe might protect against diabetes and reduce insulin resistance

NEW: One-way hydrogel guides motion of tiny worms!

Latest Posts

Feb

Gut bacteria in babies predict childhood food allergies

by adam phillips | Hot Off the Press

Scientists found that one-month-old infants with certain gut bacteria were less likely to develop food sensitivities and food allergies later in childhood.

Jan

Bye-bye microplastics: new plastic is fully ocean-degradable

by adam phillips | Hot Off the Press

A new bioplastic that dissolves in saltwater — no more pesky microplastics!

Dec

Scientists develop new and improved quantum gates

by jens wilkinson | Hot Off the Press

High-fidelity, low error quantum gates allow more reliable and accurate quantum computations, making the future of quantum computers more promising.

Dec

Nanopores in deep-sea hydrothermal vents and the origin of life

by adam phillips | Hot Off the Press

“Naturally occurring selective nanopore ion channels in deep-sea hydrothermal vents are similar to ion channels found in cells and could help explain the origin of life.

Dec

Albumin drops medicine off at cancer site then leaves the body

by masataka sasabe | Hot Off the Press

By changing albumin’s identity, drugs can carried to their targets and then removed from the body after being used.

Oct

Protein antigens in meat, milk, and other foods suppress gut tumors

by adam phillips | Hot Off the Press

Food antigens were found to prevent small intestinal tumors in gut-tumor prone mice by making ensuring we have enough T cells for defense.

Oct

Stem cell exhaustion and proliferation: An aging fly’s tale

by masataka sasabe | Hot Off the Press

Blocking the gene ced-6 led to stem cell exhaustion in aging fruit flies and prevented repair of damaged intestines.

Aug

Chromosome copying errors pinpointed in developing embryos

by adam phillips | Hot Off the Press

The DNA duplication process changes during embryogenesis and chromosome copying errors increase during the transition.

Aug

Predictive grid cells help self navigation in the brain

by adam phillips | Hot Off the Press

Scientists have discovered grid cells in the brain that map an animal’s (or human’s) future position in space.

Aug

Dopamine reduces beta-amyloid plaques in Alzheimer’s disease

by adam phillips | Hot Off the Press

Increasing dopamine in the brains of AD model mice led to increased neprilysin, which broke down amyloid-beta plaques and improved memory.

Jul

RIKEN discovers new T cells related to immune disorders

by adam phillips | Hot Off the Press

Immune-related diseases like multiple sclerosis associated with genetic variation in newly discovered, rare T cells.

Jul

Will the “love hormone” ever be used to treat a rare genetic disease?

by masataka sasabe | Drop of science, What's Up With Us

One of the pitfalls of researching an extremely rare disease: getting enough data to support clinical trials could be impossible.

Jun

Purple biomass makes a good crop fertilizer

by adam phillips | Hot Off the Press

Biomass made from purple marine bacteria provides more than enough nitrogen to plants without harming the environment

Jun

Atlas of the aging lipidome highlights kidneys and gut bacteria

by masataka sasabe | Hot Off the Press

The atlas revealed sex differences in the aging kidney lipidome and lipid byproducts of gut bacteria that accumulate throughout the body.

May

Root growth improved in soil contaminated with cesium

by masataka sasabe | Hot Off the Press

Overactivating the ABA signaling pathway in plants prevented cesium in soil from blocking root growth in plants.

May

Japanese people are a mixture of three separate ancestral groups

by jens wilkinson | Hot Off the Press

A new study shows that the current Japanese population is derived from 3 ancestral groups, one of which brought Denisovan DNA to the party.

May

Space Café Tokyo explains sus sci-fi media

by kelly | What's Up With Us

Our very own Kelly writes about how much fun she had at Space Café Tokyo. Softcore science and beer.

May

Recipe for hydrogen: sprinkle manganese oxide with iridium atoms, add water

by adam phillips | Hot Off the Press

A few iridium atoms also go a long way. When sprinkled on manganese oxide, hydrogen is produced with 95% less iridium!

May

Stable green hydrogen production in a PEM electrolyzer

by adam phillips | Hot Off the Press

A little structurally manipulated manganese goes a long way when using a PEM electrolyzer to make hydrogen from water.

Apr

Brainless memory makes the spinal cord smarter than previously thought

by adam phillips | Hot Off the Press

The spinal cord learns how to direct limb muscles to avoid aversive sensations and recalls the memories using separate neural circuitry. Oh, and without a brain!

Apr

Eco-friendly ammonia production for fertilizers and alternative fuel

by adam phillips | Hot Off the Press

A new process that allows ammonia to be produced using much less energy than the standard methods.

Apr

Cubes of brain tissue allow drug discovery without animals

by masataka sasabe | Hot Off the Press

Modeling the blood-brain-barrier with brains-in-a-cube allows drug testing without the need for animals.

Apr

Gut bacteria could help overcome milk allergy

by adam phillips | Hot Off the Press

Analysis shows that some gut bacteria could help improve oral immunotherapy against milk allergy.

Apr

Detecting pathogens: the evolution of plant immunity

by masataka sasabe | Hot Off the Press

Scientists find recognition receptors for plant growth and plant immunity that share a common evolutionary origin.

Mar

Genomic “butterfly effect” involving TADs explains risk for autism

by masataka sasabe | Hot Off the Press

De novo mutations in three-dimensional structures in the genome containing known ASD genes were found to be associated with ASD risk.

Mar

Heat used to transform antiskyrmions to skyrmions and back

by jens wilkinson | Hot Off the Press

Scientists discover a way to transform antiskyrmions to skyrmions and back using heat and magnetic fields.

Jan

Real webshooters? Synthetic spider silk spun from artificial gland

by adam phillips | Hot Off the Press

Scientists create a microfluidic device that spins artificial spider silk from spidroins proteins, duplicating silk’s complex molecular structure.

Jan

Omics Omics Omics: Analysis predicts ovarian cancer-treating drug

by adam phillips | Hot Off the Press

Multi-omics analysis prediction: drugs that inhibit Ras signaling will help prevent tumor formation in serous ovarian cancer.

Dec

First hydride-ion battery that works at room temperature

by adam phillips | Hot Off the Press

Researchers develop a new solid electrolyte that can conduct hydride ions, thus allowing better hydrogen-based batteries and fuel cells.

Nov

Plants to the rescue: cleaning up our dirty soil

by adam phillips | Drop of science

A brief review of phytoremediation and research into how plants can be used to clean the environment.

Nov

Stolen genes used for parasitic mind control

by masataka sasabe | Hot Off the Press

Parasitic horsehair worms evolved to control their praying mantis hosts by stealing their genes (horizontal gene transfer).

Sep

Machine learning contributes to better quantum error correction

by jens wilkinson | Hot Off the Press

Researchers have developed an autonomous method for handling error correction in quantum computing. This will help quantum computers maintain their advantages over standard computers.

Sep

Laser melting ice-core sampler for studying climate change

by adam phillips | Hot Off the Press

This laser melting ice core sampler can determine temperature changes thousands of years ago on very fine timescale.

Aug

Gut bacteria reduces insulin resistance, protects against diabetes

by adam phillips | Hot Off the Press

Scientists discover gut bacteria that reduce insulin resistance in your body and sugar in your poo.

Aug

Scary places burned into our minds by constant memory replay

by riken research highlights | Research Highlight

Researchers discover the mechanism through which places associated with negative experiences are burned into our memories.

Aug

Toward human hibernation: cold-resistant mouse stem cells

by adam phillips | Hot Off the Press

Cold-resistant stem cells from “deep torpor” mice are a big step toward understanding why tissue survives hibernation.

Aug

A researcher’s journey part 2: emotional memory and being human

by adam phillips | Interviews

Joshua Johansen from RIKEN CBS explains emotional memory, what his lab is doing, and what makes a good researcher.

Aug

Mathematical model predicts self-organized learning in real neurons

by adam phillips | Hot Off the Press

The free energy principle predicted how real neural connections changed as neurons “learned” in a dish.

Aug

Deadly fungi beaten with fatty acid synthase inhibitor

by adam phillips | Hot Off the Press

A new approach to attacking fungi involves inhibiting a gene needed for making fatty acids.

Flies use fecal deposits as pheromones

Bioluminescence imaging of fly brains reveals neurons sensitive to fly poo laced with pheromones (you can see the fecal “landmark” in the dotted circle). Need we say more?

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The free-energy principle explains neural network behavior

Scientists show that the free-energy principle can explain how neural networks work.

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CAPON links Alzheimer’s plaques to neurodegeneration

CAPON was found to link Aβ plaques and hippocampal neurodegeneration in mice, explaining how these two hallmarks of Alzheimer’s disease are related.

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Stolen genes used for parasitic mind control

Parasitic horsehair worms evolved to control their praying mantis hosts by stealing their genes (horizontal gene transfer).

Read on

Diazoxide pills for Alzheimer’s disease?

Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.

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Something smells fishy: categorizing odors in the brain

Calcium imaging and mathematical model explain how categories and mixtures of odors are represented in the fly brain and consistent across individual flies.

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Feb

Gut bacteria in babies predict childhood food allergies

by adam phillips | Hot Off the Press

Scientists found that one-month-old infants with certain gut bacteria were less likely to develop food sensitivities and food allergies later in childhood.

Jan

Bye-bye microplastics: new plastic is fully ocean-degradable

by adam phillips | Hot Off the Press

A new bioplastic that dissolves in saltwater — no more pesky microplastics!

Dec

Scientists develop new and improved quantum gates

by jens wilkinson | Hot Off the Press

High-fidelity, low error quantum gates allow more reliable and accurate quantum computations, making the future of quantum computers more promising.

Dec

Nanopores in deep-sea hydrothermal vents and the origin of life

by adam phillips | Hot Off the Press

“Naturally occurring selective nanopore ion channels in deep-sea hydrothermal vents are similar to ion channels found in cells and could help explain the origin of life.

Dec

Albumin drops medicine off at cancer site then leaves the body

by masataka sasabe | Hot Off the Press

By changing albumin’s identity, drugs can carried to their targets and then removed from the body after being used.

Oct

Protein antigens in meat, milk, and other foods suppress gut tumors

by adam phillips | Hot Off the Press

Food antigens were found to prevent small intestinal tumors in gut-tumor prone mice by making ensuring we have enough T cells for defense.

Oct

Stem cell exhaustion and proliferation: An aging fly’s tale

by masataka sasabe | Hot Off the Press

Blocking the gene ced-6 led to stem cell exhaustion in aging fruit flies and prevented repair of damaged intestines.

Aug

Chromosome copying errors pinpointed in developing embryos

by adam phillips | Hot Off the Press

The DNA duplication process changes during embryogenesis and chromosome copying errors increase during the transition.

Aug

Predictive grid cells help self navigation in the brain

by adam phillips | Hot Off the Press

Scientists have discovered grid cells in the brain that map an animal’s (or human’s) future position in space.

Transgenic plants ??on acid survive without water

Scientists designed transgenic plants that survive drought-like conditions by bumping up acetic acid production only when water is scarce.

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Super-thin wearable electronics just got more flexible

A method for making super-flexible and ultra-thin wearable electronics uses water-vapor plasma to create gold-gold bonds.

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Eating a high fat diet without getting obese?

Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.

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Opossums are the first genome edited marsupials

A new piezoelectronic microinjection method has allowed the first successful genome editing in marsupials: albino opossums.

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Feb

Gut bacteria in babies predict childhood food allergies

by adam phillips | Hot Off the Press

Scientists found that one-month-old infants with certain gut bacteria were less likely to develop food sensitivities and food allergies later in childhood.

Jan

Bye-bye microplastics: new plastic is fully ocean-degradable

by adam phillips | Hot Off the Press

A new bioplastic that dissolves in saltwater — no more pesky microplastics!

Dec

Scientists develop new and improved quantum gates

by jens wilkinson | Hot Off the Press

High-fidelity, low error quantum gates allow more reliable and accurate quantum computations, making the future of quantum computers more promising.

Dec

Nanopores in deep-sea hydrothermal vents and the origin of life

by adam phillips | Hot Off the Press

“Naturally occurring selective nanopore ion channels in deep-sea hydrothermal vents are similar to ion channels found in cells and could help explain the origin of life.