ERRg predicts atrial fibrillation and hidden comorbidity

Polygenic risk scores based on the genetic data from more that a million people predicted atrial fibrillation, stroke, and mortality.

Smoker gut bacteria reduce bowel inflammation in ulcerative colitis


Mouth bacteria that settle in the guts of smokers activate helper T-cells that counter inflammation in ulcerative colitis.

Nanocarrier spray: better crops without genetic modification


Gene expression, but not genomes, altered in plants and crops with a spray containing bioactive molecules tethered to nanocarrier peptides

Talking science Illustration with Misaki Ouchida


Whether it’s bird anatomy or science cartoons, Masaki Ouchida can do it all. She spoke with us about her career in science illustration, from the US to Japan.

Toward human hibernation: cold-resistant mouse stem cells


Cold-resistant stem cells from “deep torpor” mice are a big step toward understanding why tissue survives hibernation.

Schizophrenia biomarker (hydrogen sulfide) in human hair


Not only is hydrogen sulfide a good biomarker for schizophrenia, it’s also the culprit and a new starting point for drug discovery.

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Eve Marder: freeing knowledge, crashing neurons


None of us would get on a plane that had its parts changed in mid-air, says Eve Marder, who has spent her career probing a very specific cluster of crustacean nerve cells. Yet we are all walking around undergoing a constant turnover of cellular parts, and so are the lobsters and crabs Marder studies.

How group size affects cooperation: Insights from brain science


Using the prisoners dilemma game, brain scientists showed that larger group size reduces cooperation.

Longevity in supercentenarians linked to cytotoxic T-cells


Blood analysis in supercentenarians showed that they have many more cytotoxic CD4 T-cells than people with average life spans.

Methylation mutation directly linked to autism


A mutation in a gene needed for H3K9 methylation is directly linked to autism spectrum disorders and early neurodevelopment.

Hippocampal memory isn’t all about place cells


Scientists have found evidence that hippocampal memories of experience are not stored in place cells.

Understanding non-coding DNA: gene “enhancers”


NETCAGE is a newly developed technique for determining the structure of portions of the non-coding genome called ‘enhancers.’

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Diazoxide pills for Alzheimer’s disease?


Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.

New lab-grown retinal sheets almost ready for clinical trials


A new retinal transplant technique works by preventing bipolar cells from maturing in lab-grown retinal sheets.

New treatment assembles cancer drug inside the body


Cancer drugs assembled inside the body on cancer cells should reduce harmful side effects to other tissue.

Why (mouse) mothers take risks to protect their infants


The calcitonin receptor and its ligand amylin act in the brain to motivate mouse mothers to protect their pups, even in risky/dangerous situations.