Blocking obesity with a protein-sugar combination


Discovery of an enzyme that prevents obesity in mice through glycosylation of a protein involved fat-cell differentiation.

Getting a grip on slow but unique shark evolution


Scientists have decoded the genomes of two species of shark, bringing the grand total of sequenced shark genomes to three.

CAPON links Alzheimer’s plaques to neurodegeneration


CAPON was found to link Aβ plaques and hippocampal neurodegeneration in mice, explaining how these two hallmarks of Alzheimer’s disease are related.

Organ regeneration in the lab


Interview with Takashi Tsuji, team leader of the Laboratory for Organ Regeneration at the RIKEN Center for Developmental Biology

AdR blockers protect the brain from stroke damage


Treatment with adrenergic receptor antagonists (AdR blockers) was able to reduce stroke-related brain damage in mice and improve motor recovery.

Eating a high fat diet without getting obese?


Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.

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Hibernation-like state can protect kidneys during heart surgery


Activating Q-neurons in the mouse brain led to a hibernation-like state that protected kidneys during heart surgery.

Locating social memories in the brain


Scientists have identified where social memories are stored in the brains of mice. Mice are forgotten because memories cannot be retrieved.

Artificial gravity protects the immune system of mice in space


Mice who experienced artificial gravity on the ISS suffered less damage to their immune system (thymus) than weightless mice did.

Omics Omics Omics: Analysis predicts ovarian cancer-treating drug


Multi-omics analysis prediction: drugs that inhibit Ras signaling will help prevent tumor formation in serous ovarian cancer.

The brain’s GPS has a buddy system


In addition to encoding self location, brain cells in the rat hippocampus act like a GPS that encodes the location of other rats.

Xist knockout rescues miscarriages in mice


Xist knockout rescues miscarriages in mice whose egg cells lack H3K27me3 epigenetic instructions.

New lab-grown retinal sheets almost ready for clinical trials


A new retinal transplant technique works by preventing bipolar cells from maturing in lab-grown retinal sheets.

Artificial gravity protects the immune system of mice in space


Mice who experienced artificial gravity on the ISS suffered less damage to their immune system (thymus) than weightless mice did.

H2AK119ub1: How you inherit acquired traits from your mom


H2AK119ub1. Say that three times really fast! But seriously, it allows maternally acquired traits to be inherited.

How does gravity affect antimatter?


Scientists find that antimatter reacts to gravity the same way that regular matter does.