Dopamine reduces beta-amyloid plaques in Alzheimer’s disease


Increasing dopamine in the brains of AD model mice led to increased neprilysin, which broke down amyloid-beta plaques and improved memory.

Robotic researcher to the rescue


Masaki Watabe talks about automated robotic researchers, future robot rule, and scientific philosophy.

Decision-making during the COVID-19 pandemic


COVID-19 series — installment #2: RIKEN CBS Unit Leader Rei Akaishi talks about government decision-making during the pandemic.

Cancer cells killed with artificial glycosylated metalloenzyme


Scientists have developed two cancer therapies that use an artificial glycosylated metalloenzyme to specifically target cancer cells in mice.

Mutation protects against Alzheimer’s disease in mice


Scientists discover a deletion mutation that reduces amyloid-beta plaque formation in Alzheimer’s disease model mice.

Scientists solve epigenetic barriers to cloning


Scientists show that two epigenetic factors improve the success rate of cloning via somatic cell nuclear transfer.

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The brain’s GPS has a buddy system


In addition to encoding self location, brain cells in the rat hippocampus act like a GPS that encodes the location of other rats.

A researcher’s journey part 2: emotional memory and being human


Joshua Johansen from RIKEN CBS explains emotional memory, what his lab is doing, and what makes a good researcher.

Hibernation-like state can protect kidneys during heart surgery


Activating Q-neurons in the mouse brain led to a hibernation-like state that protected kidneys during heart surgery.

Protein antigens in meat, milk, and other foods suppress gut tumors


Food antigens were found to prevent small intestinal tumors in gut-tumor prone mice by making ensuring we have enough T cells for defense.

RIKEN Research Fall Issue


Fall is here, and with it comes the latest issue of RIKEN Research. This issue covers tactile learning during sleep, supercomputers and simulations, solar cells, fly olfaction, tumor vaccines, and more

Boosting betaine may be a treatment for schizophrenia


Supplementing model mice with glycine betaine (trimethylglycine), a compound originally derived from beets, can alleviate symptoms of schizophrenia.

Why (mouse) mothers take risks to protect their infants


The calcitonin receptor and its ligand amylin act in the brain to motivate mouse mothers to protect their pups, even in risky/dangerous situations.

How does gravity affect antimatter?


Scientists find that antimatter reacts to gravity the same way that regular matter does.

Opossums are the first genome edited marsupials


A new piezoelectronic microinjection method has allowed the first successful genome editing in marsupials: albino opossums.

Eating a high fat diet without getting obese?


Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.