The free-energy principle explains neural network behavior

Scientists show that the free-energy principle can explain how neural networks work.
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Longevity in supercentenarians linked to cytotoxic T-cells

Blood analysis in supercentenarians showed that they have many more cytotoxic CD4 T-cells than people with average life spans.
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Low-protein diet changes sperm and health of future offspring

Low-protein diets in male mice alter sperm and result in offspring that have metabolic problems like diabetes in adulthood.
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Imaging whole-body cancer metastasis at the single-cell level

A new optical clearing method allows imaging of cancer metastasis at incredibly high resolution.

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Real webshooters? Synthetic spider silk spun from artificial gland

Scientists create a microfluidic device that spins artificial spider silk from spidroins proteins, duplicating silk’s complex molecular structure.
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Bacterial drug resistance studied by robotic E. coli evolution

Experimentally evolving E. coli under pressure from a large number of antibiotics was able to identify constraints underlying evolved drug resistance.
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Plant hormone combats dehydration

Scientists show that CLE25 is a plant hormone that travels from roots to leaves and helps close stomata in times of dehydration stress.

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Melatonin in mice, circadian rhythms, and daily torpor

A new breed of lab mouse allows the study of naturally occurring melatonin. These mice will adjust better to jetlag than regular lab mice and experience daily torpor.
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Staining that lights up whole organs and bodies

Scientists have developed a staining procedure that makes see-through tissue, organs, and bodies useful.
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Atlas of the aging lipidome highlights kidneys and gut bacteria

The atlas revealed sex differences in the aging kidney lipidome and lipid byproducts of gut bacteria that accumulate throughout the body.
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Schizophrenia biomarker (hydrogen sulfide) in human hair

Not only is hydrogen sulfide a good biomarker for schizophrenia, it’s also the culprit and a new starting point for drug discovery.
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Laser melting ice-core sampler for studying climate change

This laser melting ice core sampler can determine temperature changes thousands of years ago on very fine timescale.
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New treatment assembles cancer drug inside the body

Cancer drugs assembled inside the body on cancer cells should reduce harmful side effects to other tissue.
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Social contact-seeking behavior and loneliness in the brain

Levels of the peptide amylin in the brain are related to loneliness; activating amylin neurons in the MPOA drives isolated mice to seek social contact.
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Artificial gravity protects the immune system of mice in space

Mice who experienced artificial gravity on the ISS suffered less damage to their immune system (thymus) than weightless mice did.
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Eating a high fat diet without getting obese?

Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.
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