Bacterial drug resistance studied by robotic E. coli evolution

Experimentally evolving E. coli under pressure from a large number of antibiotics was able to identify constraints underlying evolved drug resistance.
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A researcher’s journey part 2: emotional memory and being human

Joshua Johansen from RIKEN CBS explains emotional memory, what his lab is doing, and what makes a good researcher.
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Mutations, CRISPR, and spinocerebellar ataxia

Scientists discover that mutations causing the degenerative movement disorder spinocerebellar ataxia type 29 work by disrupting calcium release of neurons inside the brain.

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Cancer cells killed with artificial glycosylated metalloenzyme

Scientists have developed two cancer therapies that use an artificial glycosylated metalloenzyme to specifically target cancer cells in mice.
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Recipe for hydrogen: sprinkle manganese oxide with iridium atoms, add water

A few iridium atoms also go a long way. When sprinkled on manganese oxide, hydrogen is produced with 95% less iridium!
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Atlas of the aging lipidome highlights kidneys and gut bacteria

The atlas revealed sex differences in the aging kidney lipidome and lipid byproducts of gut bacteria that accumulate throughout the body.
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Blocking obesity with a protein-sugar combination

Discovery of an enzyme that prevents obesity in mice through glycosylation of a protein involved fat-cell differentiation.

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CAPON links Alzheimer’s plaques to neurodegeneration

CAPON was found to link Aβ plaques and hippocampal neurodegeneration in mice, explaining how these two hallmarks of Alzheimer’s disease are related.

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Xist knockout rescues miscarriages in mice

Xist knockout rescues miscarriages in mice whose egg cells lack H3K27me3 epigenetic instructions.
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Gut bacteria in babies predict childhood food allergies

Scientists found that one-month-old infants with certain gut bacteria were less likely to develop food sensitivities and food allergies later in childhood.
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Consciousness, brain connections, and the claustrum

Research shows that the claustrum acts as a ‘consciousness conductor’ that synchronizes and connects areas within the mouse brain.
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AI used to detect fetal heart problems

Researchers have developed a novel system that can automatically detect abnormalities in fetal hearts in real-time using artificial intelligence (AI). ???❤️

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Diazoxide pills for Alzheimer’s disease?

Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.
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Social contact-seeking behavior and loneliness in the brain

Levels of the peptide amylin in the brain are related to loneliness; activating amylin neurons in the MPOA drives isolated mice to seek social contact.
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Eating a high fat diet without getting obese?

Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.
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Why (mouse) mothers take risks to protect their infants

The calcitonin receptor and its ligand amylin act in the brain to motivate mouse mothers to protect their pups, even in risky/dangerous situations.
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