Protein pileup affects social behavior through altered brain signaling


When a normal cellular cleanup process is disrupted, social behavior in mice is disrupted and they start behaving in ways that resemble human symptoms of autism spectrum disorder and schizophrenia.

Astrocytes powered by norepinephrine during fear-memory formation


Norepinephrine released in the locus coeruleus during fear learning is accompanied by increased calcium and cAMP levels in nearby astrocytes.

Cubes of brain tissue allow drug discovery without animals


Modeling the blood-brain-barrier with brains-in-a-cube allows drug testing without the need for animals.

Supermassive black holes still dark and mysterious


For the first time, scientists have measured the strength of magnetic fields near supermassive black holes and something doesn’t add up.

A new type of cell death discovered in fly guts


A completely unknown type of cell death called “erebosis” has been discovered in the guts of the common fruit fly.

Detecting pathogens: the evolution of plant immunity


Scientists find recognition receptors for plant growth and plant immunity that share a common evolutionary origin.

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Genomic “butterfly effect” involving TADs explains risk for autism


De novo mutations in three-dimensional structures in the genome containing known ASD genes were found to be associated with ASD risk.

FABP4: A preschool-aged biomarker for autism


Reduced FABP4 was found in preschool-aged children with autism spectrum disorder, making it a potential new biomarker for the condition.

Understanding non-coding DNA: gene “enhancers”


NETCAGE is a newly developed technique for determining the structure of portions of the non-coding genome called ‘enhancers.’

Eve Marder: freeing knowledge, crashing neurons


None of us would get on a plane that had its parts changed in mid-air, says Eve Marder, who has spent her career probing a very specific cluster of crustacean nerve cells. Yet we are all walking around undergoing a constant turnover of cellular parts, and so are the lobsters and crabs Marder studies.

New artificial skin helps avoid animal testing


A new artificial skin that reproduces proper tension can be used to research skin function and disease while reducing the need to experiment on animals.

The free-energy principle explains neural network behavior


Scientists show that the free-energy principle can explain how neural networks work.

Eating a high fat diet without getting obese?


Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.

How does gravity affect antimatter?


Scientists find that antimatter reacts to gravity the same way that regular matter does.

Super-thin wearable electronics just got more flexible


A method for making super-flexible and ultra-thin wearable electronics uses water-vapor plasma to create gold-gold bonds.

Opossums are the first genome edited marsupials


A new piezoelectronic microinjection method has allowed the first successful genome editing in marsupials: albino opossums.