The joys of computational mass spectrometry

Scientists have developed a new automated computational mass spectrometry system that can search an organism’s entire metabolome for as-yet-unknown metabolites (potential drugs).

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FABP4: A preschool-aged biomarker for autism

Reduced FABP4 was found in preschool-aged children with autism spectrum disorder, making it a potential new biomarker for the condition.
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Boosting betaine may be a treatment for schizophrenia

Supplementing model mice with glycine betaine (trimethylglycine), a compound originally derived from beets, can alleviate symptoms of schizophrenia.
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Genomic “butterfly effect” involving TADs explains risk for autism

De novo mutations in three-dimensional structures in the genome containing known ASD genes were found to be associated with ASD risk.
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A self-powered heart monitor taped to the skin

A group of scientists have developed a human-friendly, ultra-flexible organic sensor powered by sunlight, which acts as a self-powered heart monitor.

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Smarter AI: machine learning without negative data

Scientists have developed a new method for machine learning that allows an AI to make better classifications without negative data.

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Engineering crop immunity from a receptor in pomelo fruit

Synthetic receptors derived from the pomelo fruit can help crops become immune to thousands of pathogens.
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Skipping fatty acids could be recipe for schizophrenia

Prenatal lack of omega-3 and omega-6 fatty acids linked to epigenetic changes that lead to schizophrenic symptoms in mice.

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Brain tissue kept alive for weeks with new microfluidic device

A new microfluidic device can keep tissue cultures functional for weeks on an artificial membrane
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Flies use fecal deposits as pheromones

Bioluminescence imaging of fly brains reveals neurons sensitive to fly poo laced with pheromones (you can see the fecal “landmark” in the dotted circle). Need we say more?

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Predictive grid cells help self navigation in the brain

Scientists have discovered grid cells in the brain that map an animal’s (or human’s) future position in space.
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AI identifies features associated with cancer recurrence

Artificial intelligence has successfully identified features relevant to cancer prognosis that were not previously noted by pathologists
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New treatment assembles cancer drug inside the body

Cancer drugs assembled inside the body on cancer cells should reduce harmful side effects to other tissue.
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Next stop: clinical hair regeneration

A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.
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Eating a high fat diet without getting obese?

Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.
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Why (mouse) mothers take risks to protect their infants

The calcitonin receptor and its ligand amylin act in the brain to motivate mouse mothers to protect their pups, even in risky/dangerous situations.
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