Organ regeneration in the lab

Interview with Takashi Tsuji, team leader of the Laboratory for Organ Regeneration at the RIKEN Center for Developmental Biology

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Marsupial heart regeneration ability given to mice

Regeneration of mouse hearts ? ?? after birth achieved by figuring out how it’s possible in opossums.
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Bacterial drug resistance studied by robotic E. coli evolution

Experimentally evolving E. coli under pressure from a large number of antibiotics was able to identify constraints underlying evolved drug resistance.
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Learning and unlearning to fear: The two faces of noradrenaline

Fear association and unlearning fear association require different populations of noradrenaline neurons in the locus coeruleus.

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Trigger region found for epileptic absence seizures

A mouse model shows that absence seizures are triggered by faulty connections between the cortex and fast-spiking neurons in the striatum.

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The joys of computational mass spectrometry

Scientists have developed a new automated computational mass spectrometry system that can search an organism’s entire metabolome for as-yet-unknown metabolites (potential drugs).

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Brain clock ticks differently in autism

A new brain imaging study shows that autistic severity is linked to how long certain regions of the brain store information.

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Strong emotions plus non-REM sleep equals longer-lasting perceptual memories

Perceptual memories linked to positive emotions, such as joy or happiness, are strengthened during sleep, specifically during periods of deep non-REM sleep.
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Diagnosing fetal heart disease benefits from explanatory AI

Diagnosis accuracy improved when doctors used explanatory AI to help diagnose congenital heart disease from fetal ultrasound videos.
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Imaging whole-body cancer metastasis at the single-cell level

A new optical clearing method allows imaging of cancer metastasis at incredibly high resolution.

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Consciousness, brain connections, and the claustrum

Research shows that the claustrum acts as a ‘consciousness conductor’ that synchronizes and connects areas within the mouse brain.
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Cancer cells killed with artificial glycosylated metalloenzyme

Scientists have developed two cancer therapies that use an artificial glycosylated metalloenzyme to specifically target cancer cells in mice.
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Super-thin wearable electronics just got more flexible

A method for making super-flexible and ultra-thin wearable electronics uses water-vapor plasma to create gold-gold bonds.
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Green hydrogen production for fuel cells and fertilizers

A new method of water electrolysis avoids rare metals, making hydrogen production green and sustainable.
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Next stop: clinical hair regeneration

A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.
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Diazoxide pills for Alzheimer’s disease?

Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.
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