In living color: imaging the brain with synthetic bioluminescence

A new way to image the brain from outside the head using bioluminescence.

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Stem cell exhaustion and proliferation: An aging fly’s tale

Blocking the gene ced-6 led to stem cell exhaustion in aging fruit flies and prevented repair of damaged intestines.
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Opossums are the first genome edited marsupials

A new piezoelectronic microinjection method has allowed the first successful genome editing in marsupials: albino opossums.
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ERRg predicts atrial fibrillation and hidden comorbidity

Polygenic risk scores based on the genetic data from more that a million people predicted atrial fibrillation, stroke, and mortality.
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Astrocytes powered by norepinephrine during fear-memory formation

Norepinephrine released in the locus coeruleus during fear learning is accompanied by increased calcium and cAMP levels in nearby astrocytes.
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RIKEN Research Winter Issue

It’s almost the end of the year and a here’s an early holiday present! The winter issue of RIKEN Research is here, covering plant parasites, depression, atomic clocks, and more! Enjoy!

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Promising mouse model for Ngly1 deficiency

A recent study of Ngly1 deficient mice used a secondary knockout to create double knockouts with symptoms similar to human NGLY1 deficiency.

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Transgenic plants ??on acid survive without water

Scientists designed transgenic plants that survive drought-like conditions by bumping up acetic acid production only when water is scarce.

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Memories are made of this ? ? – (Part 1)

Brain science ’round midnight episode 8: Thomas McHugh from the RIKEN Center for Brain Science discusses memories and the brain
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RIKEN Research Summer issue

A quick post to let you know that the Summer issue of RIKEN Research Magazine came out towards the end of June. This issue covers brain evolution, regenerating skin, super-clear synapses, and much much more! Enjoy!

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Learning and unlearning to fear: The two faces of noradrenaline

Fear association and unlearning fear association require different populations of noradrenaline neurons in the locus coeruleus.

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Albumin drops medicine off at cancer site then leaves the body

By changing albumin’s identity, drugs can carried to their targets and then removed from the body after being used.
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Next stop: clinical hair regeneration

A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.
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Talking science Illustration with Misaki Ouchida

Whether it’s bird anatomy or science cartoons, Masaki Ouchida can do it all. She spoke with us about her career in science illustration, from the US to Japan.
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Diazoxide pills for Alzheimer’s disease?

Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.
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Social contact-seeking behavior and loneliness in the brain

Levels of the peptide amylin in the brain are related to loneliness; activating amylin neurons in the MPOA drives isolated mice to seek social contact.
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