The It Ain't Magic Science Blog

Electrolithoautotrophs

Learn what electrolithoautotrophs are and how the scientists proved that A. ferrooxidans can use electric potential to fuel growth.

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Confronting a string of epidemics including COVID-19

COVID-19 series — installment #1: RIKEN Executive Director Shigeo Koyasu talks about epidemics and what a good response looks like.

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Running away from carbon dioxide: the terminal connection

Even fish want to avoid carbon dioxide. Now we know that they can because of chemosensation and the Terminal Nerve.

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Kleefstra syndrome in mice reversed after birth

Researchers used a postnatal supply of GLP to reverse neural and behavioral symptoms of Kleefstra syndrome in mice!

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Gray matter volume links symptoms in autism

Low gray matter volume in the posterior superior parietal lobule (pSPL) was found to correlate with specific cognitive and perceptual symptoms of autism.

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New treatment assembles cancer drug inside the body

Cancer drugs assembled inside the body on cancer cells should reduce harmful side effects to other tissue.

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Self-assembly of spider silk

This gut microbe might protect against diabetes and reduce insulin resistance

NEW: One-way hydrogel guides motion of tiny worms!

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Stolen genes used for parasitic mind control

Parasitic horsehair worms evolved to control their praying mantis hosts by stealing their genes (horizontal gene transfer).

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Engineering crop immunity from a receptor in pomelo fruit

Synthetic receptors derived from the pomelo fruit can help crops become immune to thousands of pathogens.

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How an herbal medicine protects against inflamed bowels

A Japanese herbal medicine promotes good bacteria and innate immune cells in the gut, which protects against intestinal inflammation.

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Organ regeneration in the lab

Interview with Takashi Tsuji, team leader of the Laboratory for Organ Regeneration at the RIKEN Center for Developmental Biology

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Blood cell mutations linked to leukemia are inevitable

Researchers show that blood cell mutations increase with age identify risk factors for developing leukemia in Japanese and European populations.

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New metalloenzyme system selectively targets cancer cells

Specific targeting of cancer cells and onsite drug synthesis has been achieved using a new artificial metalloenzyme delivery system.

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Nov

Nerdnite recap: When the brainbow met the boson

by admin | Drop of science

Fun times at nerdnite tokyo. Brains, bosons, and math, oh my!

Nov

Mutations, CRISPR, and spinocerebellar ataxia

by adam phillips | Hot Off the Press

Scientists discover that mutations causing the degenerative movement disorder spinocerebellar ataxia type 29 work by disrupting calcium release of neurons inside the brain.

Nov

Gene regulator that allows plant rehydration after drought

by adam phillips | Hot Off the Press

New genetic insights into the plant rehydration process: this is why your plants don’t die after you forgot to water them.

Oct

Researchers create a functional salivary gland organoid ?

by jens wilkinson | Hot Off the Press

Scientists have succeeded in growing three-dimensional salivary gland tissue that produced saliva like normal glands when implanted into mice.

Oct

Getting a grip on slow but unique shark evolution

by masataka sasabe | Hot Off the Press

Scientists have decoded the genomes of two species of shark, bringing the grand total of sequenced shark genomes to three.

Oct

Ig Nobel awards: Silly experiments that strike gold

by admin | Drop of science

Amanda writes about the Ig Nobel awards after founder Marc Abrahams visited nerdnite Tokyo. Science at its best!

Oct

A self-powered heart monitor taped to the skin

by jens wilkinson | Hot Off the Press

A group of scientists have developed a human-friendly, ultra-flexible organic sensor powered by sunlight, which acts as a self-powered heart monitor.

Sep

AI used to detect fetal heart problems

by masataka sasabe | News

Researchers have developed a novel system that can automatically detect abnormalities in fetal hearts in real-time using artificial intelligence (AI). ???❤️

Sep

Protostars that exhibit large diversity in organic compounds

by riken research highlights | Research Highlight

A survey of a molecular cloud has found that the organic chemical makeup of protostars varies considerably.

How does gravity affect antimatter?

Scientists find that antimatter reacts to gravity the same way that regular matter does.

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Eating a high fat diet without getting obese?

Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.

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Opossums are the first genome edited marsupials

A new piezoelectronic microinjection method has allowed the first successful genome editing in marsupials: albino opossums.

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New treatment assembles cancer drug inside the body

Cancer drugs assembled inside the body on cancer cells should reduce harmful side effects to other tissue.

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Nov

New artificial skin helps avoid animal testing

by masataka sasabe | Hot Off the Press

A new artificial skin that reproduces proper tension can be used to research skin function and disease while reducing the need to experiment on animals.

Oct

Social novelty in the brain: haven’t I seen you someplace before?

by adam phillips | Hot Off the Press

Social novelty and contextual novelty are segregated in the SuM region of the hypothalamus and in projections to the hippocampus, allowing memories of meeting new people to be formed separately from memories of new places.

Sep

FABP4: A preschool-aged biomarker for autism

by adam phillips | Hot Off the Press

Reduced FABP4 was found in preschool-aged children with autism spectrum disorder, making it a potential new biomarker for the condition.

Sep

Microbial infections are a parasitic plant’s dream

by adam phillips | Hot Off the Press

Parasitic plants use quinones produced by their host to attack. Now we know that crops produce quinones as an immune response against microbial infection. How can we protect crops from both kinds of attack?

Aug

Gut bacteria double team worsens symptoms of multiple sclerosis

by adam phillips | Hot Off the Press

Joint activity of two gut bacteria leads to excessive MOG-specific T-cell activity and demyelination of neurons in the spinal cord of a mouse model of multiple sclerosis.

Aug

Something smells fishy: categorizing odors in the brain

by masataka sasabe | Hot Off the Press

Calcium imaging and mathematical model explain how categories and mixtures of odors are represented in the fly brain and consistent across individual flies.

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