Methylation mutation directly linked to autism


A mutation in a gene needed for H3K9 methylation is directly linked to autism spectrum disorders and early neurodevelopment.

New lab-grown retinal sheets almost ready for clinical trials


A new retinal transplant technique works by preventing bipolar cells from maturing in lab-grown retinal sheets.

Mathematical model predicts self-organized learning in real neurons


The free energy principle predicted how real neural connections changed as neurons “learned” in a dish.

Chromosome copying errors pinpointed in developing embryos


The DNA duplication process changes during embryogenesis and chromosome copying errors increase during the transition.

Gene linked to intellectual ability affects memory replay in mice


Scientists have discovered a gene in mice that allows memory replay at rest, a process necessary for forming long-lasting memories in mice.

Blue gene regulation helps plants respond properly to light


Blue light alters some gene expression in plants by changing the transcription start sites to downstream locations.

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Genomic “butterfly effect” involving TADs explains risk for autism


De novo mutations in three-dimensional structures in the genome containing known ASD genes were found to be associated with ASD risk.

Gene regulator that allows plant rehydration after drought


New genetic insights into the plant rehydration process: this is why your plants don’t die after you forgot to water them.

Schizophrenia biomarker (hydrogen sulfide) in human hair


Not only is hydrogen sulfide a good biomarker for schizophrenia, it’s also the culprit and a new starting point for drug discovery.

Memories are made of this ? ? – (Part 1)


Brain science ’round midnight episode 8: Thomas McHugh from the RIKEN Center for Brain Science discusses memories and the brain

Godzilla-sized zooplankton for better aquafarming


Scientists have created extra large zooplankton to help feed the fish in aquafarms. The new plankton were created using an ion beam to generate mutations.

Something smells fishy: categorizing odors in the brain


Calcium imaging and mathematical model explain how categories and mixtures of odors are represented in the fly brain and consistent across individual flies.

Social contact-seeking behavior and loneliness in the brain


Levels of the peptide amylin in the brain are related to loneliness; activating amylin neurons in the MPOA drives isolated mice to seek social contact.

Talking science Illustration with Misaki Ouchida


Whether it’s bird anatomy or science cartoons, Masaki Ouchida can do it all. She spoke with us about her career in science illustration, from the US to Japan.

Diazoxide pills for Alzheimer’s disease?


Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.

Eating a high fat diet without getting obese?


Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.