The It Ain't Magic Science Blog

The joys of computational mass spectrometry

Scientists have developed a new automated computational mass spectrometry system that can search an organism’s entire metabolome for as-yet-unknown metabolites (potential drugs).

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Staining that lights up whole organs and bodies

Scientists have developed a staining procedure that makes see-through tissue, organs, and bodies useful.

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Nanopores in deep-sea hydrothermal vents and the origin of life

“Naturally occurring selective nanopore ion channels in deep-sea hydrothermal vents are similar to ion channels found in cells and could help explain the origin of life.

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Heat shock system helps dried up bug come back to life

An international collaboration has determined that cooption of the Heat Shock Factor (HSF) gene system is what allows larvae of the sleeping chironomid to be able to survive severe desiccation.

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Deadly fungi beaten with fatty acid synthase inhibitor

A new approach to attacking fungi involves inhibiting a gene needed for making fatty acids.

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How does gravity affect antimatter?

Scientists find that antimatter reacts to gravity the same way that regular matter does.

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Self-assembly of spider silk

This gut microbe might protect against diabetes and reduce insulin resistance

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Smoker gut bacteria reduce bowel inflammation in ulcerative colitis

Mouth bacteria that settle in the guts of smokers activate helper T-cells that counter inflammation in ulcerative colitis.

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Scientists create new type of self-healing material

This newly created ethylene-based material has shape memory that allows self-healing!

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Hibernation-like state can protect kidneys during heart surgery

Activating Q-neurons in the mouse brain led to a hibernation-like state that protected kidneys during heart surgery.

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Gut bacteria reduces insulin resistance, protects against diabetes

Scientists discover gut bacteria that reduce insulin resistance in your body and sugar in your poo.

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Big news in iPS cell transplants

iPS cell-derived retinal cells have been successfully transplanted from one monkey to another without need of immunosuppressant drugs.

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Cancer cells killed with artificial glycosylated metalloenzyme

Scientists have developed two cancer therapies that use an artificial glycosylated metalloenzyme to specifically target cancer cells in mice.

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Jan

Godzilla-sized zooplankton for better aquafarming

by masataka sasabe | Hot Off the Press

Scientists have created extra large zooplankton to help feed the fish in aquafarms. The new plankton were created using an ion beam to generate mutations.

Dec

Electric rays to help us map the ocean floor

by adam phillips | Hot Off the Press

Electric rays and sting rays could map the ocean floor through their natural behavior, helping us find resources and collect data on other ocean life.

Nov

Bacterial drug resistance studied by robotic E. coli evolution

by masataka sasabe | Hot Off the Press

Experimentally evolving E. coli under pressure from a large number of antibiotics was able to identify constraints underlying evolved drug resistance.

Nov

New artificial skin helps avoid animal testing

by masataka sasabe | Hot Off the Press

A new artificial skin that reproduces proper tension can be used to research skin function and disease while reducing the need to experiment on animals.

Oct

Social novelty in the brain: haven’t I seen you someplace before?

by adam phillips | Hot Off the Press

Social novelty and contextual novelty are segregated in the SuM region of the hypothalamus and in projections to the hippocampus, allowing memories of meeting new people to be formed separately from memories of new places.

Sep

FABP4: A preschool-aged biomarker for autism

by adam phillips | Hot Off the Press

Reduced FABP4 was found in preschool-aged children with autism spectrum disorder, making it a potential new biomarker for the condition.

Sep

Microbial infections are a parasitic plant’s dream

by adam phillips | Hot Off the Press

Parasitic plants use quinones produced by their host to attack. Now we know that crops produce quinones as an immune response against microbial infection. How can we protect crops from both kinds of attack?

Aug

Gut bacteria double team worsens symptoms of multiple sclerosis

by adam phillips | Hot Off the Press

Joint activity of two gut bacteria leads to excessive MOG-specific T-cell activity and demyelination of neurons in the spinal cord of a mouse model of multiple sclerosis.

Aug

Something smells fishy: categorizing odors in the brain

by masataka sasabe | Hot Off the Press

Calcium imaging and mathematical model explain how categories and mixtures of odors are represented in the fly brain and consistent across individual flies.

Social contact-seeking behavior and loneliness in the brain

Levels of the peptide amylin in the brain are related to loneliness; activating amylin neurons in the MPOA drives isolated mice to seek social contact.

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H2AK119ub1: How you inherit acquired traits from your mom

H2AK119ub1. Say that three times really fast! But seriously, it allows maternally acquired traits to be inherited.

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How does gravity affect antimatter?

Scientists find that antimatter reacts to gravity the same way that regular matter does.

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Next stop: clinical hair regeneration

A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.

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Jun

Extra “eye” movements are the key to better self-driving cars

by adam phillips | Hot Off the Press

If self-driving cars make saccades like people, they might make fewer mistakes identifying important features of the road.

May

Palaeospondylus: mystery of vertebrate evolution solved

by adam phillips | Hot Off the Press

Micro-CT scans using synchrotron radiation X-rays reveal Palaeospondylus morphology, finally allowing its placement on the evolutionary tree.

Apr

Xist knockout rescues miscarriages in mice

by adam phillips | Hot Off the Press

Xist knockout rescues miscarriages in mice whose egg cells lack H3K27me3 epigenetic instructions.

Apr

A new type of cell death discovered in fly guts

by masataka sasabe | Hot Off the Press

A completely unknown type of cell death called “erebosis” has been discovered in the guts of the common fruit fly.

Apr

Diagnosing fetal heart disease benefits from explanatory AI

by adam phillips | Hot Off the Press

Diagnosis accuracy improved when doctors used explanatory AI to help diagnose congenital heart disease from fetal ultrasound videos.

Apr

Chaos theory provides hints for controlling the weather

by jens wilkinson | Hot Off the Press

Computer simulations were used to show that small adjustments to certain variables in the weather system could modify weather phenomena such as sudden downpours.

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