The It Ain't Magic Science Blog

New treatment assembles cancer drug inside the body

Cancer drugs assembled inside the body on cancer cells should reduce harmful side effects to other tissue.

Opto-OISI: imaging connections in the living brain

A new imaging technique called opto-OISI allows scientists to non-invasively visualize where specific neurons project in the living brain.

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Astrocytes powered by norepinephrine during fear-memory formation

Norepinephrine released in the locus coeruleus during fear learning is accompanied by increased calcium and cAMP levels in nearby astrocytes.

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Tumor detection during breast cancer surgery

Scientists have developed a new way to accurately detect the margins between cancerous and non-cancerous tissue during breast cancer surgery.

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A self-powered heart monitor taped to the skin

A group of scientists have developed a human-friendly, ultra-flexible organic sensor powered by sunlight, which acts as a self-powered heart monitor.

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Quick, call Spiderman: scientists discover how spider silk is formed

A group of scientists led by researchers have discovered a key mechanism through which spider silk is formed.

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This gut microbe might protect against diabetes and reduce insulin resistance

NEW: One-way hydrogel guides motion of tiny worms!

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The free-energy principle explains neural network behavior

Scientists show that the free-energy principle can explain how neural networks work.

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Proton and antiproton still seem identical

Using a novel two-particle measurement method, scientists have measured the magnetic moment of the antiproton at a precision 350 times higher than any previous measurement.

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Zebrafish imagine a danger-free future to avoid threats in virtual reality

By imaging the brain while zebrafish “swim” in virtual reality, scientists have learned that even fish can create internal models to predict future outcomes.

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Robotic AI helps efficient growth of replacement organs

Humans team-up with a robotic AI to speed up experiments to find the best way to regrow damaged eye tissue from stem cells.

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Deep-brain exploration with nanomaterials

A new way to optogenetically activate neurons deep in the brain using infrared light and upconversion nanoparticles. It’s non-invasive!

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CAPON links Alzheimer’s plaques to neurodegeneration

CAPON was found to link Aβ plaques and hippocampal neurodegeneration in mice, explaining how these two hallmarks of Alzheimer’s disease are related.

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Jan

Godzilla-sized zooplankton for better aquafarming

by masataka sasabe | Hot Off the Press

Scientists have created extra large zooplankton to help feed the fish in aquafarms. The new plankton were created using an ion beam to generate mutations.

Dec

Electric rays to help us map the ocean floor

by adam phillips | Hot Off the Press

Electric rays and sting rays could map the ocean floor through their natural behavior, helping us find resources and collect data on other ocean life.

Nov

Bacterial drug resistance studied by robotic E. coli evolution

by masataka sasabe | Hot Off the Press

Experimentally evolving E. coli under pressure from a large number of antibiotics was able to identify constraints underlying evolved drug resistance.

Nov

New artificial skin helps avoid animal testing

by masataka sasabe | Hot Off the Press

A new artificial skin that reproduces proper tension can be used to research skin function and disease while reducing the need to experiment on animals.

Oct

Social novelty in the brain: haven’t I seen you someplace before?

by adam phillips | Hot Off the Press

Social novelty and contextual novelty are segregated in the SuM region of the hypothalamus and in projections to the hippocampus, allowing memories of meeting new people to be formed separately from memories of new places.

Sep

FABP4: A preschool-aged biomarker for autism

by adam phillips | Hot Off the Press

Reduced FABP4 was found in preschool-aged children with autism spectrum disorder, making it a potential new biomarker for the condition.

Sep

Microbial infections are a parasitic plant’s dream

by adam phillips | Hot Off the Press

Parasitic plants use quinones produced by their host to attack. Now we know that crops produce quinones as an immune response against microbial infection. How can we protect crops from both kinds of attack?

Aug

Gut bacteria double team worsens symptoms of multiple sclerosis

by adam phillips | Hot Off the Press

Joint activity of two gut bacteria leads to excessive MOG-specific T-cell activity and demyelination of neurons in the spinal cord of a mouse model of multiple sclerosis.

Aug

Something smells fishy: categorizing odors in the brain

by masataka sasabe | Hot Off the Press

Calcium imaging and mathematical model explain how categories and mixtures of odors are represented in the fly brain and consistent across individual flies.

H2AK119ub1: How you inherit acquired traits from your mom

H2AK119ub1. Say that three times really fast! But seriously, it allows maternally acquired traits to be inherited.

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Social contact-seeking behavior and loneliness in the brain

Levels of the peptide amylin in the brain are related to loneliness; activating amylin neurons in the MPOA drives isolated mice to seek social contact.

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New lab-grown retinal sheets almost ready for clinical trials

A new retinal transplant technique works by preventing bipolar cells from maturing in lab-grown retinal sheets.

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Diazoxide pills for Alzheimer’s disease?

Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.

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Jun

Extra “eye” movements are the key to better self-driving cars

by adam phillips | Hot Off the Press

If self-driving cars make saccades like people, they might make fewer mistakes identifying important features of the road.

May

Palaeospondylus: mystery of vertebrate evolution solved

by adam phillips | Hot Off the Press

Micro-CT scans using synchrotron radiation X-rays reveal Palaeospondylus morphology, finally allowing its placement on the evolutionary tree.

Apr

Xist knockout rescues miscarriages in mice

by adam phillips | Hot Off the Press

Xist knockout rescues miscarriages in mice whose egg cells lack H3K27me3 epigenetic instructions.

Apr

A new type of cell death discovered in fly guts

by masataka sasabe | Hot Off the Press

A completely unknown type of cell death called “erebosis” has been discovered in the guts of the common fruit fly.

Apr

Diagnosing fetal heart disease benefits from explanatory AI

by adam phillips | Hot Off the Press

Diagnosis accuracy improved when doctors used explanatory AI to help diagnose congenital heart disease from fetal ultrasound videos.

Apr

Chaos theory provides hints for controlling the weather

by jens wilkinson | Hot Off the Press

Computer simulations were used to show that small adjustments to certain variables in the weather system could modify weather phenomena such as sudden downpours.

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