The It Ain't Magic Science Blog

A new imaging biomarker for the aging brain

Enlarged ventricles is a sign of an aging brain. New research shows that this phenomenon can be predicted by lagging brain circulation that is detected by MRI.

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Centennial RIKEN Research

???This Spring we’ve put together a special centennial issue of RIKEN Research ???

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Dopamine reduces beta-amyloid plaques in Alzheimer’s disease

Increasing dopamine in the brains of AD model mice led to increased neprilysin, which broke down amyloid-beta plaques and improved memory.

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Opossums are the first genome edited marsupials

A new piezoelectronic microinjection method has allowed the first successful genome editing in marsupials: albino opossums.

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New rice fights off drought

Researchers have created drought resistant transgenic rice using a gene from a small Eurasian flowering plant

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A researcher’s journey part 2: emotional memory and being human

Joshua Johansen from RIKEN CBS explains emotional memory, what his lab is doing, and what makes a good researcher.

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Self-assembly of spider silk

This gut microbe might protect against diabetes and reduce insulin resistance

NEW: One-way hydrogel guides motion of tiny worms!

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Smarter AI: machine learning without negative data

Scientists have developed a new method for machine learning that allows an AI to make better classifications without negative data.

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Blood cell mutations linked to leukemia are inevitable

Researchers show that blood cell mutations increase with age identify risk factors for developing leukemia in Japanese and European populations.

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New treatment assembles cancer drug inside the body

Cancer drugs assembled inside the body on cancer cells should reduce harmful side effects to other tissue.

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Hepatoma (liver cancer) blocked by a sugar look-a-like

A sugar (fucose) analog can prevent liver cancer (hepatoma) from invading healthy liver cells.

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Hippocampal memory isn’t all about place cells

Scientists have found evidence that hippocampal memories of experience are not stored in place cells.

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Clean and green: a moss that removes lead (Pb) from water

Scientists show that the moss Funaria hygrometrica can remove harmful lead from water when in the protonema stage of development.

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Jan

Godzilla-sized zooplankton for better aquafarming

by masataka sasabe | Hot Off the Press

Scientists have created extra large zooplankton to help feed the fish in aquafarms. The new plankton were created using an ion beam to generate mutations.

Dec

Electric rays to help us map the ocean floor

by adam phillips | Hot Off the Press

Electric rays and sting rays could map the ocean floor through their natural behavior, helping us find resources and collect data on other ocean life.

Nov

Bacterial drug resistance studied by robotic E. coli evolution

by masataka sasabe | Hot Off the Press

Experimentally evolving E. coli under pressure from a large number of antibiotics was able to identify constraints underlying evolved drug resistance.

Nov

New artificial skin helps avoid animal testing

by masataka sasabe | Hot Off the Press

A new artificial skin that reproduces proper tension can be used to research skin function and disease while reducing the need to experiment on animals.

Oct

Social novelty in the brain: haven’t I seen you someplace before?

by adam phillips | Hot Off the Press

Social novelty and contextual novelty are segregated in the SuM region of the hypothalamus and in projections to the hippocampus, allowing memories of meeting new people to be formed separately from memories of new places.

Sep

FABP4: A preschool-aged biomarker for autism

by adam phillips | Hot Off the Press

Reduced FABP4 was found in preschool-aged children with autism spectrum disorder, making it a potential new biomarker for the condition.

Sep

Microbial infections are a parasitic plant’s dream

by adam phillips | Hot Off the Press

Parasitic plants use quinones produced by their host to attack. Now we know that crops produce quinones as an immune response against microbial infection. How can we protect crops from both kinds of attack?

Aug

Gut bacteria double team worsens symptoms of multiple sclerosis

by adam phillips | Hot Off the Press

Joint activity of two gut bacteria leads to excessive MOG-specific T-cell activity and demyelination of neurons in the spinal cord of a mouse model of multiple sclerosis.

Aug

Something smells fishy: categorizing odors in the brain

by masataka sasabe | Hot Off the Press

Calcium imaging and mathematical model explain how categories and mixtures of odors are represented in the fly brain and consistent across individual flies.

Green hydrogen production for fuel cells and fertilizers

A new method of water electrolysis avoids rare metals, making hydrogen production green and sustainable.

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Introducing Nikola, the emotional android boy

A new android named Nikola will help researchers study facial expressions, emotions, and social interactions.

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New lab-grown retinal sheets almost ready for clinical trials

A new retinal transplant technique works by preventing bipolar cells from maturing in lab-grown retinal sheets.

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Why (mouse) mothers take risks to protect their infants

The calcitonin receptor and its ligand amylin act in the brain to motivate mouse mothers to protect their pups, even in risky/dangerous situations.

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Jun

Extra “eye” movements are the key to better self-driving cars

by adam phillips | Hot Off the Press

If self-driving cars make saccades like people, they might make fewer mistakes identifying important features of the road.

May

Palaeospondylus: mystery of vertebrate evolution solved

by adam phillips | Hot Off the Press

Micro-CT scans using synchrotron radiation X-rays reveal Palaeospondylus morphology, finally allowing its placement on the evolutionary tree.

Apr

Xist knockout rescues miscarriages in mice

by adam phillips | Hot Off the Press

Xist knockout rescues miscarriages in mice whose egg cells lack H3K27me3 epigenetic instructions.

Apr

A new type of cell death discovered in fly guts

by masataka sasabe | Hot Off the Press

A completely unknown type of cell death called “erebosis” has been discovered in the guts of the common fruit fly.

Apr

Diagnosing fetal heart disease benefits from explanatory AI

by adam phillips | Hot Off the Press

Diagnosis accuracy improved when doctors used explanatory AI to help diagnose congenital heart disease from fetal ultrasound videos.

Apr

Chaos theory provides hints for controlling the weather

by jens wilkinson | Hot Off the Press

Computer simulations were used to show that small adjustments to certain variables in the weather system could modify weather phenomena such as sudden downpours.

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