The It Ain't Magic Science Blog

Opto-OISI: imaging connections in the living brain

A new imaging technique called opto-OISI allows scientists to non-invasively visualize where specific neurons project in the living brain.

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The brain’s GPS has a buddy system

In addition to encoding self location, brain cells in the rat hippocampus act like a GPS that encodes the location of other rats.

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Microbial infections are a parasitic plant’s dream

Parasitic plants use quinones produced by their host to attack. Now we know that crops produce quinones as an immune response against microbial infection. How can we protect crops from both kinds of attack?

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Laser melting ice-core sampler for studying climate change

This laser melting ice core sampler can determine temperature changes thousands of years ago on very fine timescale.

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Scientists solve epigenetic barriers to cloning

Scientists show that two epigenetic factors improve the success rate of cloning via somatic cell nuclear transfer.

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Next stop: clinical hair regeneration

A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.

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Self-assembly of spider silk

This gut microbe might protect against diabetes and reduce insulin resistance

NEW: One-way hydrogel guides motion of tiny worms!

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A self-powered heart monitor taped to the skin

A group of scientists have developed a human-friendly, ultra-flexible organic sensor powered by sunlight, which acts as a self-powered heart monitor.

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Protein pileup affects social behavior through altered brain signaling

When a normal cellular cleanup process is disrupted, social behavior in mice is disrupted and they start behaving in ways that resemble human symptoms of autism spectrum disorder and schizophrenia.

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Cyborg microchip valve driven by earthworm muscle

This earthworm muscle-controlled biological microelectromechanical system (bio‐MEMS) could lead the way to next-generation medical implants.

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Astrocytes powered by norepinephrine during fear-memory formation

Norepinephrine released in the locus coeruleus during fear learning is accompanied by increased calcium and cAMP levels in nearby astrocytes.

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Smoker gut bacteria reduce bowel inflammation in ulcerative colitis

Mouth bacteria that settle in the guts of smokers activate helper T-cells that counter inflammation in ulcerative colitis.

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Smarter AI: machine learning without negative data

Scientists have developed a new method for machine learning that allows an AI to make better classifications without negative data.

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Jan

Godzilla-sized zooplankton for better aquafarming

by masataka sasabe | Hot Off the Press

Scientists have created extra large zooplankton to help feed the fish in aquafarms. The new plankton were created using an ion beam to generate mutations.

Dec

Electric rays to help us map the ocean floor

by adam phillips | Hot Off the Press

Electric rays and sting rays could map the ocean floor through their natural behavior, helping us find resources and collect data on other ocean life.

Nov

Bacterial drug resistance studied by robotic E. coli evolution

by masataka sasabe | Hot Off the Press

Experimentally evolving E. coli under pressure from a large number of antibiotics was able to identify constraints underlying evolved drug resistance.

Nov

New artificial skin helps avoid animal testing

by masataka sasabe | Hot Off the Press

A new artificial skin that reproduces proper tension can be used to research skin function and disease while reducing the need to experiment on animals.

Oct

Social novelty in the brain: haven’t I seen you someplace before?

by adam phillips | Hot Off the Press

Social novelty and contextual novelty are segregated in the SuM region of the hypothalamus and in projections to the hippocampus, allowing memories of meeting new people to be formed separately from memories of new places.

Sep

FABP4: A preschool-aged biomarker for autism

by adam phillips | Hot Off the Press

Reduced FABP4 was found in preschool-aged children with autism spectrum disorder, making it a potential new biomarker for the condition.

Sep

Microbial infections are a parasitic plant’s dream

by adam phillips | Hot Off the Press

Aug

Gut bacteria double team worsens symptoms of multiple sclerosis

by adam phillips | Hot Off the Press

Joint activity of two gut bacteria leads to excessive MOG-specific T-cell activity and demyelination of neurons in the spinal cord of a mouse model of multiple sclerosis.

Aug

Something smells fishy: categorizing odors in the brain

by masataka sasabe | Hot Off the Press

Calcium imaging and mathematical model explain how categories and mixtures of odors are represented in the fly brain and consistent across individual flies.

Diazoxide pills for Alzheimer’s disease?

Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.

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Next stop: clinical hair regeneration

A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.

Read on

New treatment assembles cancer drug inside the body

Cancer drugs assembled inside the body on cancer cells should reduce harmful side effects to other tissue.

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Transgenic plants ??on acid survive without water

Scientists designed transgenic plants that survive drought-like conditions by bumping up acetic acid production only when water is scarce.

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Jun

Extra “eye” movements are the key to better self-driving cars

by adam phillips | Hot Off the Press

If self-driving cars make saccades like people, they might make fewer mistakes identifying important features of the road.

May

Palaeospondylus: mystery of vertebrate evolution solved

by adam phillips | Hot Off the Press

Micro-CT scans using synchrotron radiation X-rays reveal Palaeospondylus morphology, finally allowing its placement on the evolutionary tree.

Apr

Xist knockout rescues miscarriages in mice

by adam phillips | Hot Off the Press

Xist knockout rescues miscarriages in mice whose egg cells lack H3K27me3 epigenetic instructions.

Apr

A new type of cell death discovered in fly guts

by masataka sasabe | Hot Off the Press

A completely unknown type of cell death called “erebosis” has been discovered in the guts of the common fruit fly.

Apr

Diagnosing fetal heart disease benefits from explanatory AI

by adam phillips | Hot Off the Press

Diagnosis accuracy improved when doctors used explanatory AI to help diagnose congenital heart disease from fetal ultrasound videos.

Apr

Chaos theory provides hints for controlling the weather

by jens wilkinson | Hot Off the Press

Computer simulations were used to show that small adjustments to certain variables in the weather system could modify weather phenomena such as sudden downpours.

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