New lab-grown retinal sheets almost ready for clinical trials

A new retinal transplant technique works by preventing bipolar cells from maturing in lab-grown retinal sheets.
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RIKEN Research Winter Issue

It’s almost the end of the year and a here’s an early holiday present! The winter issue of RIKEN Research is here, covering plant parasites, depression, atomic clocks, and more! Enjoy!

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Robotic AI helps efficient growth of replacement organs

Humans team-up with a robotic AI to speed up experiments to find the best way to regrow damaged eye tissue from stem cells.
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Genomic “butterfly effect” involving TADs explains risk for autism

De novo mutations in three-dimensional structures in the genome containing known ASD genes were found to be associated with ASD risk.
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Big news in iPS cell transplants

iPS cell-derived retinal cells have been successfully transplanted from one monkey to another without need of immunosuppressant drugs.

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Plant hormone combats dehydration

Scientists show that CLE25 is a plant hormone that travels from roots to leaves and helps close stomata in times of dehydration stress.

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Opto-OISI: imaging connections in the living brain

A new imaging technique called opto-OISI allows scientists to non-invasively visualize where specific neurons project in the living brain.

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Evolution of the inner ear: insights from jawless fish

A new story for inner ear evolution based on the developmental patterning found in hagfish, one of two extant jawless vertebrates and a link to the last common ancestor of modern jawed vertebrates.

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Gene regulator that allows plant rehydration after drought

New genetic insights into the plant rehydration process: this is why your plants don’t die after you forgot to water them.

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Sphingolipid S1P: Potential new target for schizophrenia treatment

Sphingolipid S1P is reduced in brain white matter of people with schizophrenia, making S1P receptors a good target for new treatments.
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Gut bacteria reduces insulin resistance, protects against diabetes

Scientists discover gut bacteria that reduce insulin resistance in your body and sugar in your poo.
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Scientists create new type of self-healing material

This newly created ethylene-based material has shape memory that allows self-healing!

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Eating a high fat diet without getting obese?

Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.
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Transgenic plants ??on acid survive without water

Scientists designed transgenic plants that survive drought-like conditions by bumping up acetic acid production only when water is scarce.

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Social contact-seeking behavior and loneliness in the brain

Levels of the peptide amylin in the brain are related to loneliness; activating amylin neurons in the MPOA drives isolated mice to seek social contact.
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H2AK119ub1: How you inherit acquired traits from your mom

H2AK119ub1. Say that three times really fast! But seriously, it allows maternally acquired traits to be inherited.
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