The It Ain't Magic Science Blog

New metalloenzyme system selectively targets cancer cells

Specific targeting of cancer cells and onsite drug synthesis has been achieved using a new artificial metalloenzyme delivery system.

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Confronting a string of epidemics including COVID-19

COVID-19 series — installment #1: RIKEN Executive Director Shigeo Koyasu talks about epidemics and what a good response looks like.

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Brain wave synchrony can predict memory age

The degree of neuronal synchrony between the anterior cingulate cortex and the hippocampus during recall is an indication of memory age (in mice).

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Gene linked to intellectual ability affects memory replay in mice

Scientists have discovered a gene in mice that allows memory replay at rest, a process necessary for forming long-lasting memories in mice.

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Leaky plants bad for drought resistance

The KAI2 receptor for compounds found in smoke helps plants retain water and survive during drought.

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Finding real rewards in a virtual world

A new study shows that mice who learn to find goals in virtual reality use their hippocampus the same was as in the real world.

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Topics

Latest research animations

Self-assembly of spider silk

This gut microbe might protect against diabetes and reduce insulin resistance

NEW: One-way hydrogel guides motion of tiny worms!

Latest Posts

Sep

Engineering crop immunity from a receptor in pomelo fruit

by adam phillips | Hot Off the Press

Synthetic receptors derived from the pomelo fruit can help crops become immune to thousands of pathogens.

Aug

Smoker gut bacteria reduce bowel inflammation in ulcerative colitis

by adam phillips | Hot Off the Press

Mouth bacteria that settle in the guts of smokers activate helper T-cells that counter inflammation in ulcerative colitis.

Aug

Eco-friendly method yields more hydrogen storage, more ammonia

by adam phillips | Hot Off the Press

Eco-friendly way to double the amount of hydrogen stored in perovskite powder and more ammonia production.

Jul

Meeting robots with hearts and minds of their own at the Osaka Expo

by Yu Kikuchi | What's Up With Us

Yu Kikuchi talks about the RIKEN robots she recently befriended in Osaka Japan.

Jul

Millions of years of galaxy evolution simulated in mere months with the help of AI

by adam phillips | Hot Off the Press

When a machine learning AI was asked to help simulate galaxy evolution, processing time went from years to months.

Jul

Winter Hackathon and SupercomputingAsia

by Akiko Mizukoshi and Machiko Matsusue from R-CCS | News

Find out what RIKEN R-CCS has been up to!

Jun

How group size affects cooperation: Insights from brain science

by masataka sasabe | Hot Off the Press

Using the prisoners dilemma game, brain scientists showed that larger group size reduces cooperation.

May

Strong emotions plus non-REM sleep equals longer-lasting perceptual memories

by masataka sasabe | Hot Off the Press

Perceptual memories linked to positive emotions, such as joy or happiness, are strengthened during sleep, specifically during periods of deep non-REM sleep.

Feb

Gut bacteria in babies predict childhood food allergies

by adam phillips | Hot Off the Press

Scientists found that one-month-old infants with certain gut bacteria were less likely to develop food sensitivities and food allergies later in childhood.

Jan

Bye-bye microplastics: new plastic is fully ocean-degradable

by adam phillips | Hot Off the Press

A new bioplastic that dissolves in saltwater — no more pesky microplastics!

Dec

Scientists develop new and improved quantum gates

by jens wilkinson | Hot Off the Press

High-fidelity, low error quantum gates allow more reliable and accurate quantum computations, making the future of quantum computers more promising.

Dec

Nanopores in deep-sea hydrothermal vents and the origin of life

by adam phillips | Hot Off the Press

“Naturally occurring selective nanopore ion channels in deep-sea hydrothermal vents are similar to ion channels found in cells and could help explain the origin of life.

Dec

Albumin drops medicine off at cancer site then leaves the body

by masataka sasabe | Hot Off the Press

By changing albumin’s identity, drugs can carried to their targets and then removed from the body after being used.

Oct

Protein antigens in meat, milk, and other foods suppress gut tumors

by adam phillips | Hot Off the Press

Food antigens were found to prevent small intestinal tumors in gut-tumor prone mice by making ensuring we have enough T cells for defense.

Oct

Stem cell exhaustion and proliferation: An aging fly’s tale

by masataka sasabe | Hot Off the Press

Blocking the gene ced-6 led to stem cell exhaustion in aging fruit flies and prevented repair of damaged intestines.

Aug

Chromosome copying errors pinpointed in developing embryos

by adam phillips | Hot Off the Press

The DNA duplication process changes during embryogenesis and chromosome copying errors increase during the transition.

Aug

Predictive grid cells help self navigation in the brain

by adam phillips | Hot Off the Press

Scientists have discovered grid cells in the brain that map an animal’s (or human’s) future position in space.

Aug

Dopamine reduces beta-amyloid plaques in Alzheimer’s disease

by adam phillips | Hot Off the Press

Increasing dopamine in the brains of AD model mice led to increased neprilysin, which broke down amyloid-beta plaques and improved memory.

Jul

RIKEN discovers new T cells related to immune disorders

by adam phillips | Hot Off the Press

Immune-related diseases like multiple sclerosis associated with genetic variation in newly discovered, rare T cells.

Jul

Will the “love hormone” ever be used to treat a rare genetic disease?

by masataka sasabe | Drop of science, What's Up With Us

One of the pitfalls of researching an extremely rare disease: getting enough data to support clinical trials could be impossible.

Jun

Purple biomass makes a good crop fertilizer

by adam phillips | Hot Off the Press

Biomass made from purple marine bacteria provides more than enough nitrogen to plants without harming the environment

Jun

Atlas of the aging lipidome highlights kidneys and gut bacteria

by masataka sasabe | Hot Off the Press

The atlas revealed sex differences in the aging kidney lipidome and lipid byproducts of gut bacteria that accumulate throughout the body.

May

Root growth improved in soil contaminated with cesium

by masataka sasabe | Hot Off the Press

Overactivating the ABA signaling pathway in plants prevented cesium in soil from blocking root growth in plants.

May

Japanese people are a mixture of three separate ancestral groups

by jens wilkinson | Hot Off the Press

A new study shows that the current Japanese population is derived from 3 ancestral groups, one of which brought Denisovan DNA to the party.

May

Space Café Tokyo explains sus sci-fi media

by kelly | What's Up With Us

Our very own Kelly writes about how much fun she had at Space Café Tokyo. Softcore science and beer.

May

Recipe for hydrogen: sprinkle manganese oxide with iridium atoms, add water

by adam phillips | Hot Off the Press

A few iridium atoms also go a long way. When sprinkled on manganese oxide, hydrogen is produced with 95% less iridium!

May

Stable green hydrogen production in a PEM electrolyzer

by adam phillips | Hot Off the Press

A little structurally manipulated manganese goes a long way when using a PEM electrolyzer to make hydrogen from water.

Apr

Brainless memory makes the spinal cord smarter than previously thought

by adam phillips | Hot Off the Press

The spinal cord learns how to direct limb muscles to avoid aversive sensations and recalls the memories using separate neural circuitry. Oh, and without a brain!

Apr

Eco-friendly ammonia production for fertilizers and alternative fuel

by adam phillips | Hot Off the Press

A new process that allows ammonia to be produced using much less energy than the standard methods.

Apr

Cubes of brain tissue allow drug discovery without animals

by masataka sasabe | Hot Off the Press

Modeling the blood-brain-barrier with brains-in-a-cube allows drug testing without the need for animals.

Apr

Gut bacteria could help overcome milk allergy

by adam phillips | Hot Off the Press

Analysis shows that some gut bacteria could help improve oral immunotherapy against milk allergy.

Apr

Detecting pathogens: the evolution of plant immunity

by masataka sasabe | Hot Off the Press

Scientists find recognition receptors for plant growth and plant immunity that share a common evolutionary origin.

Mar

Genomic “butterfly effect” involving TADs explains risk for autism

by masataka sasabe | Hot Off the Press

De novo mutations in three-dimensional structures in the genome containing known ASD genes were found to be associated with ASD risk.

Mar

Heat used to transform antiskyrmions to skyrmions and back

by jens wilkinson | Hot Off the Press

Scientists discover a way to transform antiskyrmions to skyrmions and back using heat and magnetic fields.

Jan

Real webshooters? Synthetic spider silk spun from artificial gland

by adam phillips | Hot Off the Press

Scientists create a microfluidic device that spins artificial spider silk from spidroins proteins, duplicating silk’s complex molecular structure.

Jan

Omics Omics Omics: Analysis predicts ovarian cancer-treating drug

by adam phillips | Hot Off the Press

Multi-omics analysis prediction: drugs that inhibit Ras signaling will help prevent tumor formation in serous ovarian cancer.

Dec

First hydride-ion battery that works at room temperature

by adam phillips | Hot Off the Press

Researchers develop a new solid electrolyte that can conduct hydride ions, thus allowing better hydrogen-based batteries and fuel cells.

Nov

Plants to the rescue: cleaning up our dirty soil

by adam phillips | Drop of science

A brief review of phytoremediation and research into how plants can be used to clean the environment.

Nov

Stolen genes used for parasitic mind control

by masataka sasabe | Hot Off the Press

Parasitic horsehair worms evolved to control their praying mantis hosts by stealing their genes (horizontal gene transfer).

Crying baby? Science says walk, then sit

Recipe for success: Walk 5 min, sit 8 min, lay no-longer-crying baby down. Now you can relax.

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Astrocytes powered by norepinephrine during fear-memory formation

Norepinephrine released in the locus coeruleus during fear learning is accompanied by increased calcium and cAMP levels in nearby astrocytes.

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How an herbal medicine protects against inflamed bowels

A Japanese herbal medicine promotes good bacteria and innate immune cells in the gut, which protects against intestinal inflammation.

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Talking science Illustration with Misaki Ouchida

Whether it’s bird anatomy or science cartoons, Masaki Ouchida can do it all. She spoke with us about her career in science illustration, from the US to Japan.

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Ultraprecise clocks and the Tokyo Skytree verify Einstein’s theory of relativity

Time measured at the top and bottom of the Tokyo Skytree with ultraprecise clocks has verified the time dilation effect predicted by Einstein.

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Evolution of the inner ear: insights from jawless fish

A new story for inner ear evolution based on the developmental patterning found in hagfish, one of two extant jawless vertebrates and a link to the last common ancestor of modern jawed vertebrates.

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Sep

Engineering crop immunity from a receptor in pomelo fruit

by adam phillips | Hot Off the Press

Synthetic receptors derived from the pomelo fruit can help crops become immune to thousands of pathogens.

Aug

Smoker gut bacteria reduce bowel inflammation in ulcerative colitis

by adam phillips | Hot Off the Press

Mouth bacteria that settle in the guts of smokers activate helper T-cells that counter inflammation in ulcerative colitis.

Aug

Eco-friendly method yields more hydrogen storage, more ammonia

by adam phillips | Hot Off the Press

Eco-friendly way to double the amount of hydrogen stored in perovskite powder and more ammonia production.

Jul

Meeting robots with hearts and minds of their own at the Osaka Expo

by Yu Kikuchi | What's Up With Us

Yu Kikuchi talks about the RIKEN robots she recently befriended in Osaka Japan.

Jul

Millions of years of galaxy evolution simulated in mere months with the help of AI

by adam phillips | Hot Off the Press

When a machine learning AI was asked to help simulate galaxy evolution, processing time went from years to months.

Jul

Winter Hackathon and SupercomputingAsia

by Akiko Mizukoshi and Machiko Matsusue from R-CCS | News

Find out what RIKEN R-CCS has been up to!

Jun

How group size affects cooperation: Insights from brain science

by masataka sasabe | Hot Off the Press

Using the prisoners dilemma game, brain scientists showed that larger group size reduces cooperation.

May

Strong emotions plus non-REM sleep equals longer-lasting perceptual memories

by masataka sasabe | Hot Off the Press

Perceptual memories linked to positive emotions, such as joy or happiness, are strengthened during sleep, specifically during periods of deep non-REM sleep.

Feb

Gut bacteria in babies predict childhood food allergies

by adam phillips | Hot Off the Press

Scientists found that one-month-old infants with certain gut bacteria were less likely to develop food sensitivities and food allergies later in childhood.

Talking science Illustration with Misaki Ouchida

Whether it’s bird anatomy or science cartoons, Masaki Ouchida can do it all. She spoke with us about her career in science illustration, from the US to Japan.

Read on

New lab-grown retinal sheets almost ready for clinical trials

A new retinal transplant technique works by preventing bipolar cells from maturing in lab-grown retinal sheets.

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Next stop: clinical hair regeneration

A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.

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Social contact-seeking behavior and loneliness in the brain

Levels of the peptide amylin in the brain are related to loneliness; activating amylin neurons in the MPOA drives isolated mice to seek social contact.