RIKEN at a glance

We’ve just gotten our order of RIKEN at a Glance booklets back from the printers, and they look fantastic. Follow the link to download your electronic copy now!

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Cubes of brain tissue allow drug discovery without animals

Modeling the blood-brain-barrier with brains-in-a-cube allows drug testing without the need for animals.
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RIKEN Research Spring issue is here

Just a quick post to let you know that the Spring issue of RIKEN Research Magazine came out towards the end of March. This issue covers issues including the discovery of element 113, earth-friendly pesticides, and the secrets of a rice-killing fungal toxin. Enjoy!

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Robotic researcher to the rescue

Masaki Watabe talks about automated robotic researchers, future robot rule, and scientific philosophy.

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H2AK119ub1: How you inherit acquired traits from your mom

H2AK119ub1. Say that three times really fast! But seriously, it allows maternally acquired traits to be inherited.
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Blocking obesity with a protein-sugar combination

Discovery of an enzyme that prevents obesity in mice through glycosylation of a protein involved fat-cell differentiation.

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Learning and unlearning to fear: The two faces of noradrenaline

Fear association and unlearning fear association require different populations of noradrenaline neurons in the locus coeruleus.

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Blue gene regulation helps plants respond properly to light

Blue light alters some gene expression in plants by changing the transcription start sites to downstream locations.

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AI identifies features associated with cancer recurrence

Artificial intelligence has successfully identified features relevant to cancer prognosis that were not previously noted by pathologists
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Plant hormone combats dehydration

Scientists show that CLE25 is a plant hormone that travels from roots to leaves and helps close stomata in times of dehydration stress.

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The brain’s GPS has a buddy system

In addition to encoding self location, brain cells in the rat hippocampus act like a GPS that encodes the location of other rats.

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Japanese people are a mixture of three separate ancestral groups

A new study shows that the current Japanese population is derived from 3 ancestral groups, one of which brought Denisovan DNA to the party.
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Social contact-seeking behavior and loneliness in the brain

Levels of the peptide amylin in the brain are related to loneliness; activating amylin neurons in the MPOA drives isolated mice to seek social contact.
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Why (mouse) mothers take risks to protect their infants

The calcitonin receptor and its ligand amylin act in the brain to motivate mouse mothers to protect their pups, even in risky/dangerous situations.
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Diazoxide pills for Alzheimer’s disease?

Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.
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How does gravity affect antimatter?

Scientists find that antimatter reacts to gravity the same way that regular matter does.
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