Gut bacteria double team worsens symptoms of multiple sclerosis

Joint activity of two gut bacteria leads to excessive MOG-specific T-cell activity and demyelination of neurons in the spinal cord of a mouse model of multiple sclerosis.
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Centennial RIKEN Research

???This Spring we’ve put together a special centennial issue of RIKEN Research ???

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Predictive grid cells help self navigation in the brain

Scientists have discovered grid cells in the brain that map an animal’s (or human’s) future position in space.
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Laser melting ice-core sampler for studying climate change

This laser melting ice core sampler can determine temperature changes thousands of years ago on very fine timescale.
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Black smokers and electroecosystems

Black smokers are deep-sea hydrothermal vents found in the ocean. Now scientists believe that they may host electroecosystems in which the primary producers use electric currents as their energy source.

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Protein pileup affects social behavior through altered brain signaling

When a normal cellular cleanup process is disrupted, social behavior in mice is disrupted and they start behaving in ways that resemble human symptoms of autism spectrum disorder and schizophrenia.

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FABP4: A preschool-aged biomarker for autism

Reduced FABP4 was found in preschool-aged children with autism spectrum disorder, making it a potential new biomarker for the condition.
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Getting a grip on slow but unique shark evolution

Scientists have decoded the genomes of two species of shark, bringing the grand total of sequenced shark genomes to three.

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Flies use fecal deposits as pheromones

Bioluminescence imaging of fly brains reveals neurons sensitive to fly poo laced with pheromones (you can see the fecal “landmark” in the dotted circle). Need we say more?

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AdR blockers protect the brain from stroke damage

Treatment with adrenergic receptor antagonists (AdR blockers) was able to reduce stroke-related brain damage in mice and improve motor recovery.

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Diagnosing fetal heart disease benefits from explanatory AI

Diagnosis accuracy improved when doctors used explanatory AI to help diagnose congenital heart disease from fetal ultrasound videos.
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Sphingolipid S1P: Potential new target for schizophrenia treatment

Sphingolipid S1P is reduced in brain white matter of people with schizophrenia, making S1P receptors a good target for new treatments.
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New treatment assembles cancer drug inside the body

Cancer drugs assembled inside the body on cancer cells should reduce harmful side effects to other tissue.
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Super-thin wearable electronics just got more flexible

A method for making super-flexible and ultra-thin wearable electronics uses water-vapor plasma to create gold-gold bonds.
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Talking science Illustration with Misaki Ouchida

Whether it’s bird anatomy or science cartoons, Masaki Ouchida can do it all. She spoke with us about her career in science illustration, from the US to Japan.
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New lab-grown retinal sheets almost ready for clinical trials

A new retinal transplant technique works by preventing bipolar cells from maturing in lab-grown retinal sheets.
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