Genomic “butterfly effect” involving TADs explains risk for autism

De novo mutations in three-dimensional structures in the genome containing known ASD genes were found to be associated with ASD risk.
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Diazoxide pills for Alzheimer’s disease?

Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.
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Trigger region found for epileptic absence seizures

A mouse model shows that absence seizures are triggered by faulty connections between the cortex and fast-spiking neurons in the striatum.

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Getting a grip on slow but unique shark evolution

Scientists have decoded the genomes of two species of shark, bringing the grand total of sequenced shark genomes to three.

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Stolen genes used for parasitic mind control

Parasitic horsehair worms evolved to control their praying mantis hosts by stealing their genes (horizontal gene transfer).
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Confronting a string of epidemics including COVID-19

COVID-19 series — installment #1: RIKEN Executive Director Shigeo Koyasu talks about epidemics and what a good response looks like.
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Why (mouse) mothers take risks to protect their infants

The calcitonin receptor and its ligand amylin act in the brain to motivate mouse mothers to protect their pups, even in risky/dangerous situations.
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Stem cell exhaustion and proliferation: An aging fly’s tale

Blocking the gene ced-6 led to stem cell exhaustion in aging fruit flies and prevented repair of damaged intestines.
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Award-winning 3D images of living cells

An interview with Yuko Kiyosue, discussing the 3D images of living cells that gained her and her colleagues a recent award.

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Smoker gut bacteria reduce bowel inflammation in ulcerative colitis

Mouth bacteria that settle in the guts of smokers activate helper T-cells that counter inflammation in ulcerative colitis.
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The first drug treatment for brain aneurysms (in mice)

Scientists discover that most aneurysms result from mutations. A mouse model shows they can be treated with drugs.
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RIKEN Research Summer issue

A quick post to let you know that the Summer issue of RIKEN Research Magazine came out towards the end of June. This issue covers brain evolution, regenerating skin, super-clear synapses, and much much more! Enjoy!

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Diazoxide pills for Alzheimer’s disease?

Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.
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New lab-grown retinal sheets almost ready for clinical trials

A new retinal transplant technique works by preventing bipolar cells from maturing in lab-grown retinal sheets.
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Talking science Illustration with Misaki Ouchida

Whether it’s bird anatomy or science cartoons, Masaki Ouchida can do it all. She spoke with us about her career in science illustration, from the US to Japan.
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Artificial gravity protects the immune system of mice in space

Mice who experienced artificial gravity on the ISS suffered less damage to their immune system (thymus) than weightless mice did.
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