The It Ain't Magic Science Blog

Chromosome copying errors pinpointed in developing embryos

The DNA duplication process changes during embryogenesis and chromosome copying errors increase during the transition.

Boosting betaine may be a treatment for schizophrenia

Supplementing model mice with glycine betaine (trimethylglycine), a compound originally derived from beets, can alleviate symptoms of schizophrenia.

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Photosynthetic bacteria spin spider silk for the masses

A little genetic engineering and a special recipe allows photosynthetic bacteria to mass-produce super lightweight spider silk for use in manufacturing.

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Organ regeneration in the lab

Interview with Takashi Tsuji, team leader of the Laboratory for Organ Regeneration at the RIKEN Center for Developmental Biology

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In living color: imaging the brain with synthetic bioluminescence

A new way to image the brain from outside the head using bioluminescence.

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A quick post to let you know that the Summer issue of RIKEN Research Magazine came out towards the end of June. This issue covers brain evolution, regenerating skin, super-clear synapses, and much much more! Enjoy!

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Latest research animations

Self-assembly of spider silk

This gut microbe might protect against diabetes and reduce insulin resistance

NEW: One-way hydrogel guides motion of tiny worms!

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Clean and green: a moss that removes lead (Pb) from water

Scientists show that the moss Funaria hygrometrica can remove harmful lead from water when in the protonema stage of development.

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Brainless memory makes the spinal cord smarter than previously thought

The spinal cord learns how to direct limb muscles to avoid aversive sensations and recalls the memories using separate neural circuitry. Oh, and without a brain!

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Getting a grip on slow but unique shark evolution

Scientists have decoded the genomes of two species of shark, bringing the grand total of sequenced shark genomes to three.

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Are you “at risk” of being a habitual coffee drinker?

Several single nucleotide polymorphisms (SNPs) are related to dietary habits, including coffee, tea, tofu, and yogurt consumption.

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Social contact-seeking behavior and loneliness in the brain

Levels of the peptide amylin in the brain are related to loneliness; activating amylin neurons in the MPOA drives isolated mice to seek social contact.

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Confronting a string of epidemics including COVID-19

COVID-19 series — installment #1: RIKEN Executive Director Shigeo Koyasu talks about epidemics and what a good response looks like.

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Aug

Gut bacteria double team worsens symptoms of multiple sclerosis

by adam phillips | Hot Off the Press

Joint activity of two gut bacteria leads to excessive MOG-specific T-cell activity and demyelination of neurons in the spinal cord of a mouse model of multiple sclerosis.

Aug

Something smells fishy: categorizing odors in the brain

by masataka sasabe | Hot Off the Press

Calcium imaging and mathematical model explain how categories and mixtures of odors are represented in the fly brain and consistent across individual flies.

Jul

Photosynthetic bacteria spin spider silk for the masses

by masataka sasabe | Hot Off the Press

A little genetic engineering and a special recipe allows photosynthetic bacteria to mass-produce super lightweight spider silk for use in manufacturing.

Jun

Blood cell mutations linked to leukemia are inevitable

by adam phillips | Hot Off the Press

Researchers show that blood cell mutations increase with age identify risk factors for developing leukemia in Japanese and European populations.

Jun

Organic nitrogen in soil helps crop growth

by jens wilkinson | Hot Off the Press

Scientists used a multi-omics analysis to show that soil solarization helps crops grow because it increases organic nitrogen in the soil.

May

Consciousness, brain connections, and the claustrum

by admin | Hot Off the Press

Research shows that the claustrum acts as a ‘consciousness conductor’ that synchronizes and connects areas within the mouse brain.

May

A new imaging biomarker for the aging brain

by adam phillips | Hot Off the Press

Enlarged ventricles is a sign of an aging brain. New research shows that this phenomenon can be predicted by lagging brain circulation that is detected by MRI.

Apr

Sphingolipid S1P: Potential new target for schizophrenia treatment

by adam phillips | Hot Off the Press

Sphingolipid S1P is reduced in brain white matter of people with schizophrenia, making S1P receptors a good target for new treatments.

Apr

Staining that lights up whole organs and bodies

by masataka sasabe | Hot Off the Press

Scientists have developed a staining procedure that makes see-through tissue, organs, and bodies useful.

Why (mouse) mothers take risks to protect their infants

The calcitonin receptor and its ligand amylin act in the brain to motivate mouse mothers to protect their pups, even in risky/dangerous situations.

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Opossums are the first genome edited marsupials

A new piezoelectronic microinjection method has allowed the first successful genome editing in marsupials: albino opossums.

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Social contact-seeking behavior and loneliness in the brain

Levels of the peptide amylin in the brain are related to loneliness; activating amylin neurons in the MPOA drives isolated mice to seek social contact.

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Diazoxide pills for Alzheimer’s disease?

Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.

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Apr

Diagnosing fetal heart disease benefits from explanatory AI

by adam phillips | Hot Off the Press

Diagnosis accuracy improved when doctors used explanatory AI to help diagnose congenital heart disease from fetal ultrasound videos.

Apr

Chaos theory provides hints for controlling the weather

by jens wilkinson | Hot Off the Press

Computer simulations were used to show that small adjustments to certain variables in the weather system could modify weather phenomena such as sudden downpours.