The It Ain't Magic Science Blog

Atlas of the aging lipidome highlights kidneys and gut bacteria

The atlas revealed sex differences in the aging kidney lipidome and lipid byproducts of gut bacteria that accumulate throughout the body.

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Brain clock ticks differently in autism

A new brain imaging study shows that autistic severity is linked to how long certain regions of the brain store information.

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Cubes of brain tissue allow drug discovery without animals

Modeling the blood-brain-barrier with brains-in-a-cube allows drug testing without the need for animals.

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New mechanism allows lower energy requirement for OLED displays

Scientists have found a way to significantly reduce the amount of energy required by organic light emitting diodes (OLED) displays.

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New treatment assembles cancer drug inside the body

Cancer drugs assembled inside the body on cancer cells should reduce harmful side effects to other tissue.

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Root growth improved in soil contaminated with cesium

Overactivating the ABA signaling pathway in plants prevented cesium in soil from blocking root growth in plants.

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Self-assembly of spider silk

This gut microbe might protect against diabetes and reduce insulin resistance

NEW: One-way hydrogel guides motion of tiny worms!

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Finding real rewards in a virtual world

A new study shows that mice who learn to find goals in virtual reality use their hippocampus the same was as in the real world.

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COVID-19: Changing the way we do research

COVID-19 series — Part #4: Team Leader Aki Minoda from RIKEN IMS talks about how the pandemic has affected the way we work.

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FABP4: A preschool-aged biomarker for autism

Reduced FABP4 was found in preschool-aged children with autism spectrum disorder, making it a potential new biomarker for the condition.

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Mutation links bipolar disorder to mitochondrial disease

ANT1 mutations found in bipolar disease that affect mitochondria lead to hyperexcitable serotonergic neuronal activity in the brain.

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Protein antigens in meat, milk, and other foods suppress gut tumors

Food antigens were found to prevent small intestinal tumors in gut-tumor prone mice by making ensuring we have enough T cells for defense.

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Gut bacteria in babies predict childhood food allergies

Scientists found that one-month-old infants with certain gut bacteria were less likely to develop food sensitivities and food allergies later in childhood.

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May

Consciousness, brain connections, and the claustrum

by amanda alvarez | Hot Off the Press

Research shows that the claustrum acts as a ‘consciousness conductor’ that synchronizes and connects areas within the mouse brain.

May

A new imaging biomarker for the aging brain

by adam phillips | Hot Off the Press

Enlarged ventricles is a sign of an aging brain. New research shows that this phenomenon can be predicted by lagging brain circulation that is detected by MRI.

Apr

Sphingolipid S1P: Potential new target for schizophrenia treatment

by adam phillips | Hot Off the Press

Sphingolipid S1P is reduced in brain white matter of people with schizophrenia, making S1P receptors a good target for new treatments.

Apr

Staining that lights up whole organs and bodies

by masataka sasabe | Hot Off the Press

Scientists have developed a staining procedure that makes see-through tissue, organs, and bodies useful.

Apr

Artificial gravity protects the immune system of mice in space

by adam phillips | Featured, Research News

Mice who experienced artificial gravity on the ISS suffered less damage to their immune system (thymus) than weightless mice did.

Apr

Ultraprecise clocks and the Tokyo Skytree verify Einstein’s theory of relativity

by jens wilkinson | Hot Off the Press

Time measured at the top and bottom of the Tokyo Skytree with ultraprecise clocks has verified the time dilation effect predicted by Einstein.

Mar

Low-protein diet changes sperm and health of future offspring

by masataka sasabe | Hot Off the Press

Low-protein diets in male mice alter sperm and result in offspring that have metabolic problems like diabetes in adulthood.

Mar

Physiological origami and proper body development in flies

by masataka sasabe | Hot Off the Press

Genetics and mechanical origami in the fly embryo helps proper body development by fighting off “noisy” fluctuations is the environment.

Mar

Efficient and durable ultra-thin solar cells

by jens wilkinson | Hot Off the Press

Ultra-thin, flexible, organic solar cells that degrade less than 5 percent after 3,000 hours and an energy conversion ratio of 13%.

Opossums are the first genome edited marsupials

A new piezoelectronic microinjection method has allowed the first successful genome editing in marsupials: albino opossums.

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Eating a high fat diet without getting obese?

Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.

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Diazoxide pills for Alzheimer’s disease?

Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.

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New treatment assembles cancer drug inside the body

Cancer drugs assembled inside the body on cancer cells should reduce harmful side effects to other tissue.

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Feb

Green hydrogen production for fuel cells and fertilizers

by adam phillips | Featured, Hot Off the Press

A new method of water electrolysis avoids rare metals, making hydrogen production green and sustainable.

Feb

Social contact-seeking behavior and loneliness in the brain

by adam phillips | Featured, Hot Off the Press

Levels of the peptide amylin in the brain are related to loneliness; activating amylin neurons in the MPOA drives isolated mice to seek social contact.