Kleefstra syndrome in mice reversed after birth

Researchers used a postnatal supply of GLP to reverse neural and behavioral symptoms of Kleefstra syndrome in mice!
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Blocking obesity with a protein-sugar combination

Discovery of an enzyme that prevents obesity in mice through glycosylation of a protein involved fat-cell differentiation.

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RIKEN at a glance

We’ve just gotten our order of RIKEN at a Glance booklets back from the printers, and they look fantastic. Follow the link to download your electronic copy now!

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Schizophrenia biomarker (hydrogen sulfide) in human hair

Not only is hydrogen sulfide a good biomarker for schizophrenia, it’s also the culprit and a new starting point for drug discovery.
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Sphingolipid S1P: Potential new target for schizophrenia treatment

Sphingolipid S1P is reduced in brain white matter of people with schizophrenia, making S1P receptors a good target for new treatments.
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RIKEN Research Spring issue is here

Just a quick post to let you know that the Spring issue of RIKEN Research Magazine came out towards the end of March. This issue covers issues including the discovery of element 113, earth-friendly pesticides, and the secrets of a rice-killing fungal toxin. Enjoy!

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Self-assembly of spider silk

This gut microbe might protect against diabetes and reduce insulin resistance

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Running away from carbon dioxide: the terminal connection

Even fish want to avoid carbon dioxide. Now we know that they can because of chemosensation and the Terminal Nerve.

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Understanding non-coding DNA: gene “enhancers”

NETCAGE is a newly developed technique for determining the structure of portions of the non-coding genome called ‘enhancers.’
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Implantable blastocyst‐like cysts grown from stem cells

Embryo Organoids?! Blastocyst‐like cysts grown from pluripotent mouse stem cells were similar to natural blastocysts (early embryos).
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Artificial gravity protects the immune system of mice in space

Mice who experienced artificial gravity on the ISS suffered less damage to their immune system (thymus) than weightless mice did.
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Cyborg microchip valve driven by earthworm muscle

This earthworm muscle-controlled biological microelectromechanical system (bio‐MEMS) could lead the way to next-generation medical implants.
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Summer fun: how plants beat the heat

Scientists have discovered a gene that allows plants to cope with extreme heat by changing the composition of chloroplast membranes.
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How does gravity affect antimatter?

Scientists find that antimatter reacts to gravity the same way that regular matter does.
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Artificial gravity protects the immune system of mice in space

Mice who experienced artificial gravity on the ISS suffered less damage to their immune system (thymus) than weightless mice did.
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Diazoxide pills for Alzheimer’s disease?

Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.
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New lab-grown retinal sheets almost ready for clinical trials

A new retinal transplant technique works by preventing bipolar cells from maturing in lab-grown retinal sheets.
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