Gut bacteria double team worsens symptoms of multiple sclerosis


Joint activity of two gut bacteria leads to excessive MOG-specific T-cell activity and demyelination of neurons in the spinal cord of a mouse model of multiple sclerosis.

Simple but revolutionary modular organoids

A new way to construct complex 3D organoids without using elaborate techniques! The trick using modular cubes with hydrogel layers.

Super-thin wearable electronics just got more flexible


A method for making super-flexible and ultra-thin wearable electronics uses water-vapor plasma to create gold-gold bonds.

Stem cell exhaustion and proliferation: An aging fly’s tale


Blocking the gene ced-6 led to stem cell exhaustion in aging fruit flies and prevented repair of damaged intestines.

Mutation links bipolar disorder to mitochondrial disease


ANT1 mutations found in bipolar disease that affect mitochondria lead to hyperexcitable serotonergic neuronal activity in the brain.

Implantable blastocyst‐like cysts grown from stem cells


Embryo Organoids?! Blastocyst‐like cysts grown from pluripotent mouse stem cells were similar to natural blastocysts (early embryos).

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Self-assembly of spider silk

This gut microbe might protect against diabetes and reduce insulin resistance

NEW: One-way hydrogel guides motion of tiny worms!

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Deadly fungi beaten with fatty acid synthase inhibitor


A new approach to attacking fungi involves inhibiting a gene needed for making fatty acids.

New metalloenzyme system selectively targets cancer cells


Specific targeting of cancer cells and onsite drug synthesis has been achieved using a new artificial metalloenzyme delivery system.

Getting a grip on slow but unique shark evolution


Scientists have decoded the genomes of two species of shark, bringing the grand total of sequenced shark genomes to three.

The brain’s GPS has a buddy system


In addition to encoding self location, brain cells in the rat hippocampus act like a GPS that encodes the location of other rats.

Toward human hibernation: cold-resistant mouse stem cells


Cold-resistant stem cells from “deep torpor” mice are a big step toward understanding why tissue survives hibernation.

A faster and more sensitive antibody test for COVID-19


Fast and sensitive: A new antibody test for the COVID-19 virus. Just a pinprick of blood and results in 30 minutes.

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Artificial gravity protects the immune system of mice in space


Mice who experienced artificial gravity on the ISS suffered less damage to their immune system (thymus) than weightless mice did.

Social contact-seeking behavior and loneliness in the brain


Levels of the peptide amylin in the brain are related to loneliness; activating amylin neurons in the MPOA drives isolated mice to seek social contact.

Transgenic plants ??on acid survive without water


Scientists designed transgenic plants that survive drought-like conditions by bumping up acetic acid production only when water is scarce.

Next stop: clinical hair regeneration


A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.
Dec

11

Science communication symposium

Science communication symposium


Friday I participated in a small symposium that focused on science communication (for institutions in Japan). We discussed using social media as a means to self-publish wow! and amazing! research findings. Here are some of my thoughts about how useful this plays out in Japan.

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