Physiological origami and proper body development in flies

Genetics and mechanical origami in the fly embryo helps proper body development by fighting off “noisy” fluctuations is the environment.
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Smoker gut bacteria reduce bowel inflammation in ulcerative colitis

Mouth bacteria that settle in the guts of smokers activate helper T-cells that counter inflammation in ulcerative colitis.
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RIKEN Research Spring issue is here

Just a quick post to let you know that the Spring issue of RIKEN Research Magazine came out towards the end of March. This issue covers issues including the discovery of element 113, earth-friendly pesticides, and the secrets of a rice-killing fungal toxin. Enjoy!

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Low-protein diet changes sperm and health of future offspring

Low-protein diets in male mice alter sperm and result in offspring that have metabolic problems like diabetes in adulthood.
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Leaky plants bad for drought resistance

The KAI2 receptor for compounds found in smoke helps plants retain water and survive during drought.

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Cassava engineered to produce healthier tapioca starch

Reducing the amount of starch branching enzymes in cassava plants made more resistant and thus healthier tapioca starch.
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This gut microbe might protect against diabetes and reduce insulin resistance

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Xist knockout rescues miscarriages in mice

Xist knockout rescues miscarriages in mice whose egg cells lack H3K27me3 epigenetic instructions.
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Mutation links bipolar disorder to mitochondrial disease

ANT1 mutations found in bipolar disease that affect mitochondria lead to hyperexcitable serotonergic neuronal activity in the brain.

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Implantable blastocyst‐like cysts grown from stem cells

Embryo Organoids?! Blastocyst‐like cysts grown from pluripotent mouse stem cells were similar to natural blastocysts (early embryos).
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COVID-19: Changing the way we do research

COVID-19 series — Part #4: Team Leader Aki Minoda from RIKEN IMS talks about how the pandemic has affected the way we work.
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Schizophrenia biomarker (hydrogen sulfide) in human hair

Not only is hydrogen sulfide a good biomarker for schizophrenia, it’s also the culprit and a new starting point for drug discovery.
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Learning and unlearning to fear: The two faces of noradrenaline

Fear association and unlearning fear association require different populations of noradrenaline neurons in the locus coeruleus.

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Why (mouse) mothers take risks to protect their infants

The calcitonin receptor and its ligand amylin act in the brain to motivate mouse mothers to protect their pups, even in risky/dangerous situations.
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Eating a high fat diet without getting obese?

Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.
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How does gravity affect antimatter?

Scientists find that antimatter reacts to gravity the same way that regular matter does.
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Green hydrogen production for fuel cells and fertilizers

A new method of water electrolysis avoids rare metals, making hydrogen production green and sustainable.
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