Stem cell exhaustion and proliferation: An aging fly’s tale

Blocking the gene ced-6 led to stem cell exhaustion in aging fruit flies and prevented repair of damaged intestines.
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RIKEN Research Winter Issue

It’s almost the end of the year and a here’s an early holiday present! The winter issue of RIKEN Research is here, covering plant parasites, depression, atomic clocks, and more! Enjoy!

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Kleefstra syndrome in mice reversed after birth

Researchers used a postnatal supply of GLP to reverse neural and behavioral symptoms of Kleefstra syndrome in mice!
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Purple biomass makes a good crop fertilizer

Biomass made from purple marine bacteria provides more than enough nitrogen to plants without harming the environment
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Dopamine reduces beta-amyloid plaques in Alzheimer’s disease

Increasing dopamine in the brains of AD model mice led to increased neprilysin, which broke down amyloid-beta plaques and improved memory.
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Plant peptide spells relief from salty stress

Newly discovered plant peptide hormone can be used to protect plants from excessive environmental salt.

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Random movements help color-detecting cells form the proper pattern

Scientists have used a mathematical model to explain why zebrafish cone cells in the eye are arranged in a specific pattern in all individuals.

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Extra “eye” movements are the key to better self-driving cars

If self-driving cars make saccades like people, they might make fewer mistakes identifying important features of the road.
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Blocking obesity with a protein-sugar combination

Discovery of an enzyme that prevents obesity in mice through glycosylation of a protein involved fat-cell differentiation.

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A researcher’s journey: from surfing to studying pain

Joshua Johansen from RIKEN CBS tells us about his journey from surfer to pain researcher and beyond. Stay tuned for part II …
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CAPON links Alzheimer’s plaques to neurodegeneration

CAPON was found to link Aβ plaques and hippocampal neurodegeneration in mice, explaining how these two hallmarks of Alzheimer’s disease are related.

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Flies use fecal deposits as pheromones

Bioluminescence imaging of fly brains reveals neurons sensitive to fly poo laced with pheromones (you can see the fecal “landmark” in the dotted circle). Need we say more?

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Eating a high fat diet without getting obese?

Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.
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Green hydrogen production for fuel cells and fertilizers

A new method of water electrolysis avoids rare metals, making hydrogen production green and sustainable.
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Opossums are the first genome edited marsupials

A new piezoelectronic microinjection method has allowed the first successful genome editing in marsupials: albino opossums.
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Social contact-seeking behavior and loneliness in the brain

Levels of the peptide amylin in the brain are related to loneliness; activating amylin neurons in the MPOA drives isolated mice to seek social contact.
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