Cubes of brain tissue allow drug discovery without animals


Modeling the blood-brain-barrier with brains-in-a-cube allows drug testing without the need for animals.

RIKEN Research Spring issue is here


Just a quick post to let you know that the Spring issue of RIKEN Research Magazine came out towards the end of March. This issue covers issues including the discovery of element 113, earth-friendly pesticides, and the secrets of a rice-killing fungal toxin. Enjoy!

Flies use fecal deposits as pheromones


Bioluminescence imaging of fly brains reveals neurons sensitive to fly poo laced with pheromones (you can see the fecal “landmark” in the dotted circle). Need we say more?

Promising mouse model for Ngly1 deficiency


A recent study of Ngly1 deficient mice used a secondary knockout to create double knockouts with symptoms similar to human NGLY1 deficiency.

Social novelty in the brain: haven’t I seen you someplace before?


Social novelty and contextual novelty are segregated in the SuM region of the hypothalamus and in projections to the hippocampus, allowing memories of meeting new people to be formed separately from memories of new places.

Superfly flight simulator helps unravel navigation in the brain


Optical imaging neural activity in flies as they use a flight simulator can help us understand how the brain codes navigation.

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Extra “eye” movements are the key to better self-driving cars


If self-driving cars make saccades like people, they might make fewer mistakes identifying important features of the road.

Cyborg cockroaches to the rescue!


The key to this remote-controllable cyborg cockroach is a solar-cell rechargeable battery and an ultrathin flexible backpack.

Scientists solve epigenetic barriers to cloning


Scientists show that two epigenetic factors improve the success rate of cloning via somatic cell nuclear transfer.

Getting a grip on slow but unique shark evolution


Scientists have decoded the genomes of two species of shark, bringing the grand total of sequenced shark genomes to three.

Tape and vermilion: ingredients for mapping artifact origins


Vermilion samples taken from ancient artifacts with sulfur-free tape can tell us about trade patterns 3000 years ago.

Chromosome copying errors pinpointed in developing embryos


The DNA duplication process changes during embryogenesis and chromosome copying errors increase during the transition.

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H2AK119ub1: How you inherit acquired traits from your mom


H2AK119ub1. Say that three times really fast! But seriously, it allows maternally acquired traits to be inherited.

Green hydrogen production for fuel cells and fertilizers


A new method of water electrolysis avoids rare metals, making hydrogen production green and sustainable.

Diazoxide pills for Alzheimer’s disease?


Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.

Super-thin wearable electronics just got more flexible


A method for making super-flexible and ultra-thin wearable electronics uses water-vapor plasma to create gold-gold bonds.