Protein pileup affects social behavior through altered brain signaling


When a normal cellular cleanup process is disrupted, social behavior in mice is disrupted and they start behaving in ways that resemble human symptoms of autism spectrum disorder and schizophrenia.

Imaging whole-body cancer metastasis at the single-cell level


A new optical clearing method allows imaging of cancer metastasis at incredibly high resolution.

Memories are made of this ?? – (Part 2)


Thomas McHugh from the RIKEN Center for Brain Science continues his discussion about memories, emotions, the brain, and life.

Real webshooters? Synthetic spider silk spun from artificial gland


Scientists create a microfluidic device that spins artificial spider silk from spidroins proteins, duplicating silk’s complex molecular structure.

Physiological origami and proper body development in flies


Genetics and mechanical origami in the fly embryo helps proper body development by fighting off “noisy” fluctuations is the environment.

How does gravity affect antimatter?


Scientists find that antimatter reacts to gravity the same way that regular matter does.

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New lab-grown retinal sheets almost ready for clinical trials


A new retinal transplant technique works by preventing bipolar cells from maturing in lab-grown retinal sheets.

Telework: a societal game-changer


COVID-19 series — installment #3: Team Leader Osamu Sakura (@RIKEN Center for Advanced Intelligence Project) talks about how the pandemic has affected society through the need for telework.

Gut bacteria double team worsens symptoms of multiple sclerosis


Joint activity of two gut bacteria leads to excessive MOG-specific T-cell activity and demyelination of neurons in the spinal cord of a mouse model of multiple sclerosis.

Zebrafish imagine a danger-free future to avoid threats in virtual reality


By imaging the brain while zebrafish “swim” in virtual reality, scientists have learned that even fish can create internal models to predict future outcomes.

Opto-OISI: imaging connections in the living brain


A new imaging technique called opto-OISI allows scientists to non-invasively visualize where specific neurons project in the living brain.

Organic nitrogen in soil helps crop growth


Scientists used a multi-omics analysis to show that soil solarization helps crops grow because it increases organic nitrogen in the soil.

Social contact-seeking behavior and loneliness in the brain


Levels of the peptide amylin in the brain are related to loneliness; activating amylin neurons in the MPOA drives isolated mice to seek social contact.

Artificial gravity protects the immune system of mice in space


Mice who experienced artificial gravity on the ISS suffered less damage to their immune system (thymus) than weightless mice did.

Introducing Nikola, the emotional android boy


A new android named Nikola will help researchers study facial expressions, emotions, and social interactions.

Why (mouse) mothers take risks to protect their infants


The calcitonin receptor and its ligand amylin act in the brain to motivate mouse mothers to protect their pups, even in risky/dangerous situations.