Gut bacteria double team worsens symptoms of multiple sclerosis

Joint activity of two gut bacteria leads to excessive MOG-specific T-cell activity and demyelination of neurons in the spinal cord of a mouse model of multiple sclerosis.
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The free-energy principle explains neural network behavior

Scientists show that the free-energy principle can explain how neural networks work.
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Microcolumns: elementary neuronal units that carpet the (mouse) brain

A hexagonal lattice organizes major cell types in the cerebral cortex, with similar cells synchronizing their activity in microcolumns.

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Talking science Illustration with Misaki Ouchida

Whether it’s bird anatomy or science cartoons, Masaki Ouchida can do it all. She spoke with us about her career in science illustration, from the US to Japan.
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RIKEN Research Winter Issue

It’s almost the end of the year and a here’s an early holiday present! The winter issue of RIKEN Research is here, covering plant parasites, depression, atomic clocks, and more! Enjoy!

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Understanding non-coding DNA: gene “enhancers”

NETCAGE is a newly developed technique for determining the structure of portions of the non-coding genome called ‘enhancers.’
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New mechanism allows lower energy requirement for OLED displays

Scientists have found a way to significantly reduce the amount of energy required by organic light emitting diodes (OLED) displays.

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Evolution of the inner ear: insights from jawless fish

A new story for inner ear evolution based on the developmental patterning found in hagfish, one of two extant jawless vertebrates and a link to the last common ancestor of modern jawed vertebrates.

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New metalloenzyme system selectively targets cancer cells

Specific targeting of cancer cells and onsite drug synthesis has been achieved using a new artificial metalloenzyme delivery system.
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COVID-19: Changing the way we do research

COVID-19 series — Part #4: Team Leader Aki Minoda from RIKEN IMS talks about how the pandemic has affected the way we work.
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What’s that smell? The advantage of sniffing

Rhythmic sniffing boosts phase-coded neuronal signals in the mouse olfactory bulb that allow odors to be identified.

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Scientists solve epigenetic barriers to cloning

Scientists show that two epigenetic factors improve the success rate of cloning via somatic cell nuclear transfer.

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New treatment assembles cancer drug inside the body

Cancer drugs assembled inside the body on cancer cells should reduce harmful side effects to other tissue.
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Next stop: clinical hair regeneration

A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.
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New lab-grown retinal sheets almost ready for clinical trials

A new retinal transplant technique works by preventing bipolar cells from maturing in lab-grown retinal sheets.
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Eating a high fat diet without getting obese?

Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.
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