Mutation links bipolar disorder to mitochondrial disease

ANT1 mutations found in bipolar disease that affect mitochondria lead to hyperexcitable serotonergic neuronal activity in the brain.

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Leaky plants bad for drought resistance

The KAI2 receptor for compounds found in smoke helps plants retain water and survive during drought.

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Memories are made of this ? ? – (Part 1)

Brain science ’round midnight episode 8: Thomas McHugh from the RIKEN Center for Brain Science discusses memories and the brain
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Blood cell mutations linked to leukemia are inevitable

Researchers show that blood cell mutations increase with age identify risk factors for developing leukemia in Japanese and European populations.
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Schizophrenia biomarker (hydrogen sulfide) in human hair

Not only is hydrogen sulfide a good biomarker for schizophrenia, it’s also the culprit and a new starting point for drug discovery.
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From evolutionary morphology to Godzilla

I recently spoke with RIKEN scientist Shigeru Kuratani about evolutionary morphology, sci-fi monsters, the genius of Alien, and more.

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Dopamine reduces beta-amyloid plaques in Alzheimer’s disease

Increasing dopamine in the brains of AD model mice led to increased neprilysin, which broke down amyloid-beta plaques and improved memory.
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CAPON links Alzheimer’s plaques to neurodegeneration

CAPON was found to link Aβ plaques and hippocampal neurodegeneration in mice, explaining how these two hallmarks of Alzheimer’s disease are related.

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Two genes that regulate how much we dream

An international research team led by RIKEN BDR has identified a pair of genes that regulate how much REM (dream) and non-REM sleep an animal experiences.

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Astrocytes powered by norepinephrine during fear-memory formation

Norepinephrine released in the locus coeruleus during fear learning is accompanied by increased calcium and cAMP levels in nearby astrocytes.
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Eating a high fat diet without getting obese?

Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.
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RIKEN Research Fall Issue

Fall is here, and with it comes the latest issue of RIKEN Research. This issue covers tactile learning during sleep, supercomputers and simulations, solar cells, fly olfaction, tumor vaccines, and more

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Transgenic plants ??on acid survive without water

Scientists designed transgenic plants that survive drought-like conditions by bumping up acetic acid production only when water is scarce.

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Artificial gravity protects the immune system of mice in space

Mice who experienced artificial gravity on the ISS suffered less damage to their immune system (thymus) than weightless mice did.
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Social contact-seeking behavior and loneliness in the brain

Levels of the peptide amylin in the brain are related to loneliness; activating amylin neurons in the MPOA drives isolated mice to seek social contact.
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How does gravity affect antimatter?

Scientists find that antimatter reacts to gravity the same way that regular matter does.
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