Social novelty in the brain: haven’t I seen you someplace before?


Social novelty and contextual novelty are segregated in the SuM region of the hypothalamus and in projections to the hippocampus, allowing memories of meeting new people to be formed separately from memories of new places.

Mutation links bipolar disorder to mitochondrial disease


ANT1 mutations found in bipolar disease that affect mitochondria lead to hyperexcitable serotonergic neuronal activity in the brain.

Toward human hibernation: cold-resistant mouse stem cells


Cold-resistant stem cells from “deep torpor” mice are a big step toward understanding why tissue survives hibernation.

Hibernation-like state can protect kidneys during heart surgery


Activating Q-neurons in the mouse brain led to a hibernation-like state that protected kidneys during heart surgery.

Decision-making during the COVID-19 pandemic


COVID-19 series — installment #2: RIKEN CBS Unit Leader Rei Akaishi talks about government decision-making during the pandemic.

Root growth improved in soil contaminated with cesium


Overactivating the ABA signaling pathway in plants prevented cesium in soil from blocking root growth in plants.

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Brainless memory makes the spinal cord smarter than previously thought


The spinal cord learns how to direct limb muscles to avoid aversive sensations and recalls the memories using separate neural circuitry. Oh, and without a brain!

Protein antigens in meat, milk, and other foods suppress gut tumors


Food antigens were found to prevent small intestinal tumors in gut-tumor prone mice by making ensuring we have enough T cells for defense.

Japanese people are a mixture of three separate ancestral groups


A new study shows that the current Japanese population is derived from 3 ancestral groups, one of which brought Denisovan DNA to the party.

Organ regeneration in the lab


Interview with Takashi Tsuji, team leader of the Laboratory for Organ Regeneration at the RIKEN Center for Developmental Biology

Sphingolipid S1P: Potential new target for schizophrenia treatment


Sphingolipid S1P is reduced in brain white matter of people with schizophrenia, making S1P receptors a good target for new treatments.

A researcher’s journey part 2: emotional memory and being human


Joshua Johansen from RIKEN CBS explains emotional memory, what his lab is doing, and what makes a good researcher.

H2AK119ub1: How you inherit acquired traits from your mom


H2AK119ub1. Say that three times really fast! But seriously, it allows maternally acquired traits to be inherited.

Talking science Illustration with Misaki Ouchida


Whether it’s bird anatomy or science cartoons, Masaki Ouchida can do it all. She spoke with us about her career in science illustration, from the US to Japan.

Next stop: clinical hair regeneration


A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.

Social contact-seeking behavior and loneliness in the brain


Levels of the peptide amylin in the brain are related to loneliness; activating amylin neurons in the MPOA drives isolated mice to seek social contact.