Methylation mutation directly linked to autism

A mutation in a gene needed for H3K9 methylation is directly linked to autism spectrum disorders and early neurodevelopment.
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Tape and vermilion: ingredients for mapping artifact origins

Vermilion samples taken from ancient artifacts with sulfur-free tape can tell us about trade patterns 3000 years ago.
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RIKEN Research Summer issue

A quick post to let you know that the Summer issue of RIKEN Research Magazine came out towards the end of June. This issue covers brain evolution, regenerating skin, super-clear synapses, and much much more! Enjoy!

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Protein pileup affects social behavior through altered brain signaling

When a normal cellular cleanup process is disrupted, social behavior in mice is disrupted and they start behaving in ways that resemble human symptoms of autism spectrum disorder and schizophrenia.

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New treatment assembles cancer drug inside the body

Cancer drugs assembled inside the body on cancer cells should reduce harmful side effects to other tissue.
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A new type of cell death discovered in fly guts

A completely unknown type of cell death called “erebosis” has been discovered in the guts of the common fruit fly.
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Promising mouse model for Ngly1 deficiency

A recent study of Ngly1 deficient mice used a secondary knockout to create double knockouts with symptoms similar to human NGLY1 deficiency.

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Gut bacteria double team worsens symptoms of multiple sclerosis

Joint activity of two gut bacteria leads to excessive MOG-specific T-cell activity and demyelination of neurons in the spinal cord of a mouse model of multiple sclerosis.
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Bacterial drug resistance studied by robotic E. coli evolution

Experimentally evolving E. coli under pressure from a large number of antibiotics was able to identify constraints underlying evolved drug resistance.
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Marsupial heart regeneration ability given to mice

Regeneration of mouse hearts ? ?? after birth achieved by figuring out how it’s possible in opossums.
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Blocking obesity with a protein-sugar combination

Discovery of an enzyme that prevents obesity in mice through glycosylation of a protein involved fat-cell differentiation.

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Researchers create a functional salivary gland organoid ?

Scientists have succeeded in growing three-dimensional salivary gland tissue that produced saliva like normal glands when implanted into mice.

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How does gravity affect antimatter?

Scientists find that antimatter reacts to gravity the same way that regular matter does.
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Why (mouse) mothers take risks to protect their infants

The calcitonin receptor and its ligand amylin act in the brain to motivate mouse mothers to protect their pups, even in risky/dangerous situations.
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Opossums are the first genome edited marsupials

A new piezoelectronic microinjection method has allowed the first successful genome editing in marsupials: albino opossums.
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Artificial gravity protects the immune system of mice in space

Mice who experienced artificial gravity on the ISS suffered less damage to their immune system (thymus) than weightless mice did.
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