Genomic “butterfly effect” involving TADs explains risk for autism


De novo mutations in three-dimensional structures in the genome containing known ASD genes were found to be associated with ASD risk.

Mutation links bipolar disorder to mitochondrial disease


ANT1 mutations found in bipolar disease that affect mitochondria lead to hyperexcitable serotonergic neuronal activity in the brain.

Random movements help color-detecting cells form the proper pattern


Scientists have used a mathematical model to explain why zebrafish cone cells in the eye are arranged in a specific pattern in all individuals.

Getting a grip on slow but unique shark evolution


Scientists have decoded the genomes of two species of shark, bringing the grand total of sequenced shark genomes to three.

ERRg predicts atrial fibrillation and hidden comorbidity

Polygenic risk scores based on the genetic data from more that a million people predicted atrial fibrillation, stroke, and mortality.

Detecting pathogens: the evolution of plant immunity


Scientists find recognition receptors for plant growth and plant immunity that share a common evolutionary origin.

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Longevity in supercentenarians linked to cytotoxic T-cells


Blood analysis in supercentenarians showed that they have many more cytotoxic CD4 T-cells than people with average life spans.

Chromosome copying errors pinpointed in developing embryos


The DNA duplication process changes during embryogenesis and chromosome copying errors increase during the transition.

Researchers create a functional salivary gland organoid ?


Scientists have succeeded in growing three-dimensional salivary gland tissue that produced saliva like normal glands when implanted into mice.

Eve Marder: freeing knowledge, crashing neurons


None of us would get on a plane that had its parts changed in mid-air, says Eve Marder, who has spent her career probing a very specific cluster of crustacean nerve cells. Yet we are all walking around undergoing a constant turnover of cellular parts, and so are the lobsters and crabs Marder studies.

Low-protein diet changes sperm and health of future offspring


Low-protein diets in male mice alter sperm and result in offspring that have metabolic problems like diabetes in adulthood.

Big news in iPS cell transplants


iPS cell-derived retinal cells have been successfully transplanted from one monkey to another without need of immunosuppressant drugs.

Next stop: clinical hair regeneration


A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.

How does gravity affect antimatter?


Scientists find that antimatter reacts to gravity the same way that regular matter does.

Transgenic plants ??on acid survive without water


Scientists designed transgenic plants that survive drought-like conditions by bumping up acetic acid production only when water is scarce.

Diazoxide pills for Alzheimer’s disease?


Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.