The joys of computational mass spectrometry

Scientists have developed a new automated computational mass spectrometry system that can search an organism’s entire metabolome for as-yet-unknown metabolites (potential drugs).

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Diazoxide pills for Alzheimer’s disease?

Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.
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CAPON links Alzheimer’s plaques to neurodegeneration

CAPON was found to link Aβ plaques and hippocampal neurodegeneration in mice, explaining how these two hallmarks of Alzheimer’s disease are related.

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Genomic “butterfly effect” involving TADs explains risk for autism

De novo mutations in three-dimensional structures in the genome containing known ASD genes were found to be associated with ASD risk.
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What’s that smell? The advantage of sniffing

Rhythmic sniffing boosts phase-coded neuronal signals in the mouse olfactory bulb that allow odors to be identified.

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First hydride-ion battery that works at room temperature

Researchers develop a new solid electrolyte that can conduct hydride ions, thus allowing better hydrogen-based batteries and fuel cells.
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Nanopores in deep-sea hydrothermal vents and the origin of life

“Naturally occurring selective nanopore ion channels in deep-sea hydrothermal vents are similar to ion channels found in cells and could help explain the origin of life.
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Getting a grip on slow but unique shark evolution

Scientists have decoded the genomes of two species of shark, bringing the grand total of sequenced shark genomes to three.

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The brain’s GPS has a buddy system

In addition to encoding self location, brain cells in the rat hippocampus act like a GPS that encodes the location of other rats.

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Stolen genes used for parasitic mind control

Parasitic horsehair worms evolved to control their praying mantis hosts by stealing their genes (horizontal gene transfer).
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A new and improved way to store hydrogen

A simple chemical reaction allows hydrogen-carrying ammonia to be stored and retrieved cheaply and easily.
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Protein antigens in meat, milk, and other foods suppress gut tumors

Food antigens were found to prevent small intestinal tumors in gut-tumor prone mice by making ensuring we have enough T cells for defense.
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New treatment assembles cancer drug inside the body

Cancer drugs assembled inside the body on cancer cells should reduce harmful side effects to other tissue.
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Eating a high fat diet without getting obese?

Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.
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Opossums are the first genome edited marsupials

A new piezoelectronic microinjection method has allowed the first successful genome editing in marsupials: albino opossums.
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Why (mouse) mothers take risks to protect their infants

The calcitonin receptor and its ligand amylin act in the brain to motivate mouse mothers to protect their pups, even in risky/dangerous situations.
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