Organ regeneration in the lab

Interview with Takashi Tsuji, team leader of the Laboratory for Organ Regeneration at the RIKEN Center for Developmental Biology

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Melatonin in mice, circadian rhythms, and daily torpor

A new breed of lab mouse allows the study of naturally occurring melatonin. These mice will adjust better to jetlag than regular lab mice and experience daily torpor.
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Dietary amino acid linked to cancer in flies

Researchers have found a dietary amino acid linked to oncogene expression / tumor formation; reduced consumption reduced cancer in flies.
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Atlas of the aging lipidome highlights kidneys and gut bacteria

The atlas revealed sex differences in the aging kidney lipidome and lipid byproducts of gut bacteria that accumulate throughout the body.
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Blocking obesity with a protein-sugar combination

Discovery of an enzyme that prevents obesity in mice through glycosylation of a protein involved fat-cell differentiation.

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Random movements help color-detecting cells form the proper pattern

Scientists have used a mathematical model to explain why zebrafish cone cells in the eye are arranged in a specific pattern in all individuals.

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AI identifies features associated with cancer recurrence

Artificial intelligence has successfully identified features relevant to cancer prognosis that were not previously noted by pathologists
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Summer fun: how plants beat the heat

Scientists have discovered a gene that allows plants to cope with extreme heat by changing the composition of chloroplast membranes.
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Blocking obesity with a protein-sugar combination

Discovery of an enzyme that prevents obesity in mice through glycosylation of a protein involved fat-cell differentiation.

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Bacterial drug resistance studied by robotic E. coli evolution

Experimentally evolving E. coli under pressure from a large number of antibiotics was able to identify constraints underlying evolved drug resistance.
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Toward human hibernation: cold-resistant mouse stem cells

Cold-resistant stem cells from “deep torpor” mice are a big step toward understanding why tissue survives hibernation.
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Kleefstra syndrome in mice reversed after birth

Researchers used a postnatal supply of GLP to reverse neural and behavioral symptoms of Kleefstra syndrome in mice!
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Next stop: clinical hair regeneration

A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.
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Diazoxide pills for Alzheimer’s disease?

Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.
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Eating a high fat diet without getting obese?

Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.
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Why (mouse) mothers take risks to protect their infants

The calcitonin receptor and its ligand amylin act in the brain to motivate mouse mothers to protect their pups, even in risky/dangerous situations.
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