Kleefstra syndrome in mice reversed after birth


Researchers used a postnatal supply of GLP to reverse neural and behavioral symptoms of Kleefstra syndrome in mice!

RIKEN discovers new T cells related to immune disorders


Immune-related diseases like multiple sclerosis associated with genetic variation in newly discovered, rare T cells.

A researcher’s journey part 2: emotional memory and being human


Joshua Johansen from RIKEN CBS explains emotional memory, what his lab is doing, and what makes a good researcher.

Astrocytes powered by norepinephrine during fear-memory formation


Norepinephrine released in the locus coeruleus during fear learning is accompanied by increased calcium and cAMP levels in nearby astrocytes.

Hepatoma (liver cancer) blocked by a sugar look-a-like


A sugar (fucose) analog can prevent liver cancer (hepatoma) from invading healthy liver cells.

Photosynthetic bacteria spin spider silk for the masses


A little genetic engineering and a special recipe allows photosynthetic bacteria to mass-produce super lightweight spider silk for use in manufacturing.

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Self-assembly of spider silk

This gut microbe might protect against diabetes and reduce insulin resistance

NEW: One-way hydrogel guides motion of tiny worms!

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New metalloenzyme system selectively targets cancer cells


Specific targeting of cancer cells and onsite drug synthesis has been achieved using a new artificial metalloenzyme delivery system.

Transgenic plants ??on acid survive without water


Scientists designed transgenic plants that survive drought-like conditions by bumping up acetic acid production only when water is scarce.

Memories are made of this ?? – (Part 2)


Thomas McHugh from the RIKEN Center for Brain Science continues his discussion about memories, emotions, the brain, and life.

The joys of computational mass spectrometry


Scientists have developed a new automated computational mass spectrometry system that can search an organism’s entire metabolome for as-yet-unknown metabolites (potential drugs).

Skipping fatty acids could be recipe for schizophrenia


Prenatal lack of omega-3 and omega-6 fatty acids linked to epigenetic changes that lead to schizophrenic symptoms in mice.

Introducing Nikola, the emotional android boy


A new android named Nikola will help researchers study facial expressions, emotions, and social interactions.

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Why (mouse) mothers take risks to protect their infants


The calcitonin receptor and its ligand amylin act in the brain to motivate mouse mothers to protect their pups, even in risky/dangerous situations.

Diazoxide pills for Alzheimer’s disease?


Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.

H2AK119ub1: How you inherit acquired traits from your mom


H2AK119ub1. Say that three times really fast! But seriously, it allows maternally acquired traits to be inherited.

New treatment assembles cancer drug inside the body


Cancer drugs assembled inside the body on cancer cells should reduce harmful side effects to other tissue.