RIKEN Research Spring issue is here

Just a quick post to let you know that the Spring issue of RIKEN Research Magazine came out towards the end of March. This issue covers issues including the discovery of element 113, earth-friendly pesticides, and the secrets of a rice-killing fungal toxin. Enjoy!

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Promising mouse model for Ngly1 deficiency

A recent study of Ngly1 deficient mice used a secondary knockout to create double knockouts with symptoms similar to human NGLY1 deficiency.

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Freedom from fear ?‍♀️

Researchers discover a dopaminergic circuit in the brain that allows fear associations to disappear when there isn’t anything to be afraid of anymore.

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FABP4: A preschool-aged biomarker for autism

Reduced FABP4 was found in preschool-aged children with autism spectrum disorder, making it a potential new biomarker for the condition.
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Mutation protects against Alzheimer’s disease in mice

Scientists discover a deletion mutation that reduces amyloid-beta plaque formation in Alzheimer’s disease model mice.

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Blood cell mutations linked to leukemia are inevitable

Researchers show that blood cell mutations increase with age identify risk factors for developing leukemia in Japanese and European populations.
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Mini-EUSO launched to the International Space Station ?

The Mini-EUSO observatory was successfully launched to the International Space Station aboard the Soyuz MS14! NASA video inside!
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Gray matter volume links symptoms in autism

Low gray matter volume in the posterior superior parietal lobule (pSPL) was found to correlate with specific cognitive and perceptual symptoms of autism.
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Flies smell through a gore-tex system

The newly named gore-tex gene is responsible for the development of nanopores that allow chemicals in the air to be detected (in flies).

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Real webshooters? Synthetic spider silk spun from artificial gland

Scientists create a microfluidic device that spins artificial spider silk from spidroins proteins, duplicating silk’s complex molecular structure.
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Deadly fungi beaten with fatty acid synthase inhibitor

A new approach to attacking fungi involves inhibiting a gene needed for making fatty acids.
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Extra “eye” movements are the key to better self-driving cars

If self-driving cars make saccades like people, they might make fewer mistakes identifying important features of the road.
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How does gravity affect antimatter?

Scientists find that antimatter reacts to gravity the same way that regular matter does.
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Eating a high fat diet without getting obese?

Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.
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Social contact-seeking behavior and loneliness in the brain

Levels of the peptide amylin in the brain are related to loneliness; activating amylin neurons in the MPOA drives isolated mice to seek social contact.
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Artificial gravity protects the immune system of mice in space

Mice who experienced artificial gravity on the ISS suffered less damage to their immune system (thymus) than weightless mice did.
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