Hippocampal memory isn’t all about place cells


Scientists have found evidence that hippocampal memories of experience are not stored in place cells.

Heat shock system helps dried up bug come back to life


An international collaboration has determined that cooption of the Heat Shock Factor (HSF) gene system is what allows larvae of the sleeping chironomid to be able to survive severe desiccation.

A researcher’s journey: from surfing to studying pain


Joshua Johansen from RIKEN CBS tells us about his journey from surfer to pain researcher and beyond. Stay tuned for part II …

Mutation links bipolar disorder to mitochondrial disease


ANT1 mutations found in bipolar disease that affect mitochondria lead to hyperexcitable serotonergic neuronal activity in the brain.

Gut bacteria double team worsens symptoms of multiple sclerosis


Joint activity of two gut bacteria leads to excessive MOG-specific T-cell activity and demyelination of neurons in the spinal cord of a mouse model of multiple sclerosis.

Brainless memory makes the spinal cord smarter than previously thought


The spinal cord learns how to direct limb muscles to avoid aversive sensations and recalls the memories using separate neural circuitry. Oh, and without a brain!

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Hibernation-like state can protect kidneys during heart surgery


Activating Q-neurons in the mouse brain led to a hibernation-like state that protected kidneys during heart surgery.

Laser melting ice-core sampler for studying climate change


This laser melting ice core sampler can determine temperature changes thousands of years ago on very fine timescale.

Promising mouse model for Ngly1 deficiency


A recent study of Ngly1 deficient mice used a secondary knockout to create double knockouts with symptoms similar to human NGLY1 deficiency.

How does gravity affect antimatter?


Scientists find that antimatter reacts to gravity the same way that regular matter does.

Mutation protects against Alzheimer’s disease in mice


Scientists discover a deletion mutation that reduces amyloid-beta plaque formation in Alzheimer’s disease model mice.

Trigger region found for epileptic absence seizures


A mouse model shows that absence seizures are triggered by faulty connections between the cortex and fast-spiking neurons in the striatum.

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H2AK119ub1: How you inherit acquired traits from your mom


H2AK119ub1. Say that three times really fast! But seriously, it allows maternally acquired traits to be inherited.

Social contact-seeking behavior and loneliness in the brain


Levels of the peptide amylin in the brain are related to loneliness; activating amylin neurons in the MPOA drives isolated mice to seek social contact.

Why (mouse) mothers take risks to protect their infants


The calcitonin receptor and its ligand amylin act in the brain to motivate mouse mothers to protect their pups, even in risky/dangerous situations.

Diazoxide pills for Alzheimer’s disease?


Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.