The It Ain't Magic Science Blog

Omics Omics Omics: Analysis predicts ovarian cancer-treating drug

Multi-omics analysis prediction: drugs that inhibit Ras signaling will help prevent tumor formation in serous ovarian cancer.

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Diazoxide pills for Alzheimer’s disease?

Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.

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Memories are made of this ?? – (Part 2)

Thomas McHugh from the RIKEN Center for Brain Science continues his discussion about memories, emotions, the brain, and life.

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Chromosome copying errors pinpointed in developing embryos

The DNA duplication process changes during embryogenesis and chromosome copying errors increase during the transition.

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New rice fights off drought

Researchers have created drought resistant transgenic rice using a gene from a small Eurasian flowering plant

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Plant peptide spells relief from salty stress

Newly discovered plant peptide hormone can be used to protect plants from excessive environmental salt.

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Latest research animations

Self-assembly of spider silk

This gut microbe might protect against diabetes and reduce insulin resistance

NEW: One-way hydrogel guides motion of tiny worms!

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Next stop: clinical hair regeneration

A new recipe for continuous cyclical hair regeneration in mice. This means that the hair will continue to fall out and regrow like normal hair.

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The first drug treatment for brain aneurysms (in mice)

Scientists discover that most aneurysms result from mutations. A mouse model shows they can be treated with drugs.

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Gut bacteria in babies predict childhood food allergies

Scientists found that one-month-old infants with certain gut bacteria were less likely to develop food sensitivities and food allergies later in childhood.

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Tumor detection during breast cancer surgery

Scientists have developed a new way to accurately detect the margins between cancerous and non-cancerous tissue during breast cancer surgery.

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Atlas of the aging lipidome highlights kidneys and gut bacteria

The atlas revealed sex differences in the aging kidney lipidome and lipid byproducts of gut bacteria that accumulate throughout the body.

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Methylation mutation directly linked to autism

A mutation in a gene needed for H3K9 methylation is directly linked to autism spectrum disorders and early neurodevelopment.

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Jul

Cyborg microchip valve driven by earthworm muscle

by adam phillips | Hot Off the Press

This earthworm muscle-controlled biological microelectromechanical system (bio‐MEMS) could lead the way to next-generation medical implants.

Jul

Eating a high fat diet without getting obese?

by adam phillips | Featured, Hot Off the Press

Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.

Jul

New metalloenzyme system selectively targets cancer cells

by masataka sasabe | Hot Off the Press

Specific targeting of cancer cells and onsite drug synthesis has been achieved using a new artificial metalloenzyme delivery system.

Jun

Boosting betaine may be a treatment for schizophrenia

by admin | Hot Off the Press

Supplementing model mice with glycine betaine (trimethylglycine), a compound originally derived from beets, can alleviate symptoms of schizophrenia.

Jun

Gray matter volume links symptoms in autism

by adam phillips | Hot Off the Press

Low gray matter volume in the posterior superior parietal lobule (pSPL) was found to correlate with specific cognitive and perceptual symptoms of autism.

Jun

New mechanism allows lower energy requirement for OLED displays

by jens wilkinson | Hot Off the Press

Scientists have found a way to significantly reduce the amount of energy required by organic light emitting diodes (OLED) displays.

Jun

CAPON links Alzheimer’s plaques to neurodegeneration

by adam phillips | Hot Off the Press

CAPON was found to link Aβ plaques and hippocampal neurodegeneration in mice, explaining how these two hallmarks of Alzheimer’s disease are related.

May

AdR blockers protect the brain from stroke damage

by admin | Hot Off the Press

Treatment with adrenergic receptor antagonists (AdR blockers) was able to reduce stroke-related brain damage in mice and improve motor recovery.

Apr

Trigger region found for epileptic absence seizures

by adam phillips | Hot Off the Press

A mouse model shows that absence seizures are triggered by faulty connections between the cortex and fast-spiking neurons in the striatum.

Talking science Illustration with Misaki Ouchida

Whether it’s bird anatomy or science cartoons, Masaki Ouchida can do it all. She spoke with us about her career in science illustration, from the US to Japan.

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Why (mouse) mothers take risks to protect their infants

The calcitonin receptor and its ligand amylin act in the brain to motivate mouse mothers to protect their pups, even in risky/dangerous situations.

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Transgenic plants ??on acid survive without water

Scientists designed transgenic plants that survive drought-like conditions by bumping up acetic acid production only when water is scarce.

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New treatment assembles cancer drug inside the body

Cancer drugs assembled inside the body on cancer cells should reduce harmful side effects to other tissue.

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Jul

Methylation mutation directly linked to autism

by adam phillips | Hot Off the Press

A mutation in a gene needed for H3K9 methylation is directly linked to autism spectrum disorders and early neurodevelopment.

Jun

Melatonin in mice, circadian rhythms, and daily torpor

by admin | Hot Off the Press

A new breed of lab mouse allows the study of naturally occurring melatonin. These mice will adjust better to jetlag than regular lab mice and experience daily torpor.