The It Ain't Magic Science Blog

Deep-brain exploration with nanomaterials

A new way to optogenetically activate neurons deep in the brain using infrared light and upconversion nanoparticles. It’s non-invasive!

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Consciousness, brain connections, and the claustrum

Research shows that the claustrum acts as a ‘consciousness conductor’ that synchronizes and connects areas within the mouse brain.

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Cassava engineered to produce healthier tapioca starch

Reducing the amount of starch branching enzymes in cassava plants made more resistant and thus healthier tapioca starch.

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Big news in iPS cell transplants

iPS cell-derived retinal cells have been successfully transplanted from one monkey to another without need of immunosuppressant drugs.

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Longevity in supercentenarians linked to cytotoxic T-cells

Blood analysis in supercentenarians showed that they have many more cytotoxic CD4 T-cells than people with average life spans.

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Talking science Illustration with Misaki Ouchida

Whether it’s bird anatomy or science cartoons, Masaki Ouchida can do it all. She spoke with us about her career in science illustration, from the US to Japan.

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Latest research animations

Self-assembly of spider silk

This gut microbe might protect against diabetes and reduce insulin resistance

NEW: One-way hydrogel guides motion of tiny worms!

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Microcolumns: elementary neuronal units that carpet the (mouse) brain

A hexagonal lattice organizes major cell types in the cerebral cortex, with similar cells synchronizing their activity in microcolumns.

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Confronting a string of epidemics including COVID-19

COVID-19 series — installment #1: RIKEN Executive Director Shigeo Koyasu talks about epidemics and what a good response looks like.

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How an herbal medicine protects against inflamed bowels

A Japanese herbal medicine promotes good bacteria and innate immune cells in the gut, which protects against intestinal inflammation.

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Imaging whole-body cancer metastasis at the single-cell level

A new optical clearing method allows imaging of cancer metastasis at incredibly high resolution.

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Laser melting ice-core sampler for studying climate change

This laser melting ice core sampler can determine temperature changes thousands of years ago on very fine timescale.

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Robotic exoskeleton learns to help people stand up

This new robotic exoskeleton uses machine learning to know when users want help standing up.

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Jul

Cyborg microchip valve driven by earthworm muscle

by adam phillips | Hot Off the Press

This earthworm muscle-controlled biological microelectromechanical system (bio‐MEMS) could lead the way to next-generation medical implants.

Jul

Eating a high fat diet without getting obese?

by adam phillips | Featured, Hot Off the Press

Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.

Jul

New metalloenzyme system selectively targets cancer cells

by masataka sasabe | Hot Off the Press

Specific targeting of cancer cells and onsite drug synthesis has been achieved using a new artificial metalloenzyme delivery system.

Jun

Boosting betaine may be a treatment for schizophrenia

by admin | Hot Off the Press

Supplementing model mice with glycine betaine (trimethylglycine), a compound originally derived from beets, can alleviate symptoms of schizophrenia.

Jun

Gray matter volume links symptoms in autism

by adam phillips | Hot Off the Press

Low gray matter volume in the posterior superior parietal lobule (pSPL) was found to correlate with specific cognitive and perceptual symptoms of autism.

Jun

New mechanism allows lower energy requirement for OLED displays

by jens wilkinson | Hot Off the Press

Scientists have found a way to significantly reduce the amount of energy required by organic light emitting diodes (OLED) displays.

Jun

CAPON links Alzheimer’s plaques to neurodegeneration

by adam phillips | Hot Off the Press

CAPON was found to link Aβ plaques and hippocampal neurodegeneration in mice, explaining how these two hallmarks of Alzheimer’s disease are related.

May

AdR blockers protect the brain from stroke damage

by admin | Hot Off the Press

Treatment with adrenergic receptor antagonists (AdR blockers) was able to reduce stroke-related brain damage in mice and improve motor recovery.

Apr

Trigger region found for epileptic absence seizures

by adam phillips | Hot Off the Press

A mouse model shows that absence seizures are triggered by faulty connections between the cortex and fast-spiking neurons in the striatum.

Opossums are the first genome edited marsupials

A new piezoelectronic microinjection method has allowed the first successful genome editing in marsupials: albino opossums.

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Artificial gravity protects the immune system of mice in space

Mice who experienced artificial gravity on the ISS suffered less damage to their immune system (thymus) than weightless mice did.

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H2AK119ub1: How you inherit acquired traits from your mom

H2AK119ub1. Say that three times really fast! But seriously, it allows maternally acquired traits to be inherited.

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How does gravity affect antimatter?

Scientists find that antimatter reacts to gravity the same way that regular matter does.

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Jul

Methylation mutation directly linked to autism

by adam phillips | Hot Off the Press

A mutation in a gene needed for H3K9 methylation is directly linked to autism spectrum disorders and early neurodevelopment.

Jun

Melatonin in mice, circadian rhythms, and daily torpor

by admin | Hot Off the Press

A new breed of lab mouse allows the study of naturally occurring melatonin. These mice will adjust better to jetlag than regular lab mice and experience daily torpor.