The It Ain't Magic Science Blog

Eating a high fat diet without getting obese?

Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.

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Hippocampal memory isn’t all about place cells

Scientists have found evidence that hippocampal memories of experience are not stored in place cells.

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Kleefstra syndrome in mice reversed after birth

Researchers used a postnatal supply of GLP to reverse neural and behavioral symptoms of Kleefstra syndrome in mice!

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Clean and green: a moss that removes lead (Pb) from water

Scientists show that the moss Funaria hygrometrica can remove harmful lead from water when in the protonema stage of development.

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Atlas of the aging lipidome highlights kidneys and gut bacteria

The atlas revealed sex differences in the aging kidney lipidome and lipid byproducts of gut bacteria that accumulate throughout the body.

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Dopamine reduces beta-amyloid plaques in Alzheimer’s disease

Increasing dopamine in the brains of AD model mice led to increased neprilysin, which broke down amyloid-beta plaques and improved memory.

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Self-assembly of spider silk

This gut microbe might protect against diabetes and reduce insulin resistance

NEW: One-way hydrogel guides motion of tiny worms!

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RIKEN Research Fall Issue

Fall is here, and with it comes the latest issue of RIKEN Research. This issue covers tactile learning during sleep, supercomputers and simulations, solar cells, fly olfaction, tumor vaccines, and more

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Learning and unlearning to fear: The two faces of noradrenaline

Fear association and unlearning fear association require different populations of noradrenaline neurons in the locus coeruleus.

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A new and improved way to store hydrogen

A simple chemical reaction allows hydrogen-carrying ammonia to be stored and retrieved cheaply and easily.

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Root growth improved in soil contaminated with cesium

Overactivating the ABA signaling pathway in plants prevented cesium in soil from blocking root growth in plants.

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Scientists solve epigenetic barriers to cloning

Scientists show that two epigenetic factors improve the success rate of cloning via somatic cell nuclear transfer.

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Eco-friendly method yields more hydrogen storage, more ammonia

Eco-friendly way to double the amount of hydrogen stored in perovskite powder and more ammonia production.

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Jul

Cyborg microchip valve driven by earthworm muscle

by adam phillips | Hot Off the Press

This earthworm muscle-controlled biological microelectromechanical system (bio‐MEMS) could lead the way to next-generation medical implants.

Jul

Eating a high fat diet without getting obese?

by adam phillips | Featured, Hot Off the Press

Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.

Jul

New metalloenzyme system selectively targets cancer cells

by masataka sasabe | Hot Off the Press

Specific targeting of cancer cells and onsite drug synthesis has been achieved using a new artificial metalloenzyme delivery system.

Jun

Boosting betaine may be a treatment for schizophrenia

by admin | Hot Off the Press

Supplementing model mice with glycine betaine (trimethylglycine), a compound originally derived from beets, can alleviate symptoms of schizophrenia.

Jun

Gray matter volume links symptoms in autism

by adam phillips | Hot Off the Press

Low gray matter volume in the posterior superior parietal lobule (pSPL) was found to correlate with specific cognitive and perceptual symptoms of autism.

Jun

New mechanism allows lower energy requirement for OLED displays

by jens wilkinson | Hot Off the Press

Scientists have found a way to significantly reduce the amount of energy required by organic light emitting diodes (OLED) displays.

Jun

CAPON links Alzheimer’s plaques to neurodegeneration

by adam phillips | Hot Off the Press

CAPON was found to link Aβ plaques and hippocampal neurodegeneration in mice, explaining how these two hallmarks of Alzheimer’s disease are related.

May

AdR blockers protect the brain from stroke damage

by admin | Hot Off the Press

Treatment with adrenergic receptor antagonists (AdR blockers) was able to reduce stroke-related brain damage in mice and improve motor recovery.

Apr

Trigger region found for epileptic absence seizures

by adam phillips | Hot Off the Press

A mouse model shows that absence seizures are triggered by faulty connections between the cortex and fast-spiking neurons in the striatum.

New lab-grown retinal sheets almost ready for clinical trials

A new retinal transplant technique works by preventing bipolar cells from maturing in lab-grown retinal sheets.

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Diazoxide pills for Alzheimer’s disease?

Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.

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Eating a high fat diet without getting obese?

Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.

Read on

Opossums are the first genome edited marsupials

A new piezoelectronic microinjection method has allowed the first successful genome editing in marsupials: albino opossums.

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Jul

Methylation mutation directly linked to autism

by adam phillips | Hot Off the Press

A mutation in a gene needed for H3K9 methylation is directly linked to autism spectrum disorders and early neurodevelopment.

Jun

Melatonin in mice, circadian rhythms, and daily torpor

by admin | Hot Off the Press

A new breed of lab mouse allows the study of naturally occurring melatonin. These mice will adjust better to jetlag than regular lab mice and experience daily torpor.