Superfly flight simulator helps unravel navigation in the brain

Optical imaging neural activity in flies as they use a flight simulator can help us understand how the brain codes navigation.

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Bacterial drug resistance studied by robotic E. coli evolution

Experimentally evolving E. coli under pressure from a large number of antibiotics was able to identify constraints underlying evolved drug resistance.
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Learning and unlearning to fear: The two faces of noradrenaline

Fear association and unlearning fear association require different populations of noradrenaline neurons in the locus coeruleus.

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Mutations, CRISPR, and spinocerebellar ataxia

Scientists discover that mutations causing the degenerative movement disorder spinocerebellar ataxia type 29 work by disrupting calcium release of neurons inside the brain.

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Cancer cells killed with artificial glycosylated metalloenzyme

Scientists have developed two cancer therapies that use an artificial glycosylated metalloenzyme to specifically target cancer cells in mice.
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New treatment assembles cancer drug inside the body

Cancer drugs assembled inside the body on cancer cells should reduce harmful side effects to other tissue.
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Hippocampal memory isn’t all about place cells

Scientists have found evidence that hippocampal memories of experience are not stored in place cells.

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Palaeospondylus: mystery of vertebrate evolution solved

Micro-CT scans using synchrotron radiation X-rays reveal Palaeospondylus morphology, finally allowing its placement on the evolutionary tree.
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Hepatoma (liver cancer) blocked by a sugar look-a-like

A sugar (fucose) analog can prevent liver cancer (hepatoma) from invading healthy liver cells.

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Telework: a societal game-changer

COVID-19 series — installment #3: Team Leader Osamu Sakura (@RIKEN Center for Advanced Intelligence Project) talks about how the pandemic has affected society through the need for telework.
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Sphingolipid S1P: Potential new target for schizophrenia treatment

Sphingolipid S1P is reduced in brain white matter of people with schizophrenia, making S1P receptors a good target for new treatments.
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RIKEN Research Summer issue

A quick post to let you know that the Summer issue of RIKEN Research Magazine came out towards the end of June. This issue covers brain evolution, regenerating skin, super-clear synapses, and much much more! Enjoy!

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New treatment assembles cancer drug inside the body

Cancer drugs assembled inside the body on cancer cells should reduce harmful side effects to other tissue.
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H2AK119ub1: How you inherit acquired traits from your mom

H2AK119ub1. Say that three times really fast! But seriously, it allows maternally acquired traits to be inherited.
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Transgenic plants ??on acid survive without water

Scientists designed transgenic plants that survive drought-like conditions by bumping up acetic acid production only when water is scarce.

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Eating a high fat diet without getting obese?

Scientists discover that without innate immune cells in the intestines, eating a high fat diet does not lead to obesity in mice.
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