Blood cell mutations linked to leukemia are inevitable


Researchers show that blood cell mutations increase with age identify risk factors for developing leukemia in Japanese and European populations.

Boosting betaine may be a treatment for schizophrenia


Supplementing model mice with glycine betaine (trimethylglycine), a compound originally derived from beets, can alleviate symptoms of schizophrenia.

Learning and unlearning to fear: The two faces of noradrenaline


Fear association and unlearning fear association require different populations of noradrenaline neurons in the locus coeruleus.

Albumin drops medicine off at cancer site then leaves the body


By changing albumin’s identity, drugs can carried to their targets and then removed from the body after being used.

AI identifies features associated with cancer recurrence


Artificial intelligence has successfully identified features relevant to cancer prognosis that were not previously noted by pathologists

Nanopores in deep-sea hydrothermal vents and the origin of life


“Naturally occurring selective nanopore ion channels in deep-sea hydrothermal vents are similar to ion channels found in cells and could help explain the origin of life.

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Memories are made of this ?? – (Part 2)


Thomas McHugh from the RIKEN Center for Brain Science continues his discussion about memories, emotions, the brain, and life.

RIKEN discovers new T cells related to immune disorders


Immune-related diseases like multiple sclerosis associated with genetic variation in newly discovered, rare T cells.

Massive filaments, galaxies, and supermassive black holes


Big telescopes yield big data! Detailed observations gas filaments connecting galaxies in a distant proto-cluster in the early Universe.

New metalloenzyme system selectively targets cancer cells


Specific targeting of cancer cells and onsite drug synthesis has been achieved using a new artificial metalloenzyme delivery system.

Something smells fishy: categorizing odors in the brain


Calcium imaging and mathematical model explain how categories and mixtures of odors are represented in the fly brain and consistent across individual flies.

Protein pileup affects social behavior through altered brain signaling


When a normal cellular cleanup process is disrupted, social behavior in mice is disrupted and they start behaving in ways that resemble human symptoms of autism spectrum disorder and schizophrenia.

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Artificial gravity protects the immune system of mice in space


Mice who experienced artificial gravity on the ISS suffered less damage to their immune system (thymus) than weightless mice did.

Diazoxide pills for Alzheimer’s disease?


Drug therapy with with diazoxide relieved symptoms of Alzheimer’s disease in the brains of mice and improved memory.

Why (mouse) mothers take risks to protect their infants


The calcitonin receptor and its ligand amylin act in the brain to motivate mouse mothers to protect their pups, even in risky/dangerous situations.

New lab-grown retinal sheets almost ready for clinical trials


A new retinal transplant technique works by preventing bipolar cells from maturing in lab-grown retinal sheets.